Tejal Desai, PhD

Professor

Deborah Cowan Endowed Professor

Director, Health Innovation via Engineering (HIVE)

Department of Bioengineering and Therapeutic Sciences

[email protected]

Phone: +1 415 514-4503

Fax: +1 415 514-9656

1700 4th Street, Rm 203C

UCSF Box 2520

San Francisco, CA 94158

United States

Links

Desai Lab UCSF Profiles

Affiliations

What I do

I am a bioengineer focusing on micro and nanofabrication techniques to create new devices for drug and cell delivery as well as biomaterials for cell and tissue regeneration. I am the immediate past chair of seven years of the Department of Bioengineering and Therapeutic Sciences, a joint department in the UCSF Schools of Pharmacy and Medicine.

Departmental research area

therapeutic bioengineering

My research expertise

biomedical microtechnology, biomedical nanotechnology, cell-material interactions, tissue repair and regeneration, biomimetic architectures, drug delivery, oral drug delivery, ocular drug delivery, biomaterials, Nanostructured materials

Professional background

Biography

Tejal Desai is the Deborah Cowan Endowed Professor, Department of Bioengineering & Therapeutic Sciences, Schools of Pharmacy and Medicine at University of California, San Francisco (UCSF); and Professor in Residence, Department of Bioengineering, UC Berkeley (UCB). She serves as director of the NIH training grant for the Joint UCSF/UCB Graduate Program in Bioengineering, and founding director of the UCSF/UCB Masters Program in Translational Medicine. She is also the Inaugural Director of the UCSF Engineering and Applied Sciences Initiative known as HIVE (Health Innovation Via Engineering).

Desai is the immediate past chair (7 years) of the Department of Bioengineering & Therapeutic Sciences.

Desai’s research spans multiple disciplines including materials engineering, cell biology, tissue engineering, and pharmacological delivery systems to develop new therapeutic interventions for disease. She seeks to design new platforms, enabled by advancements in micro and nanotechnology, to overcome existing challenges in therapeutic delivery. She has published over 250 peer-reviewed articles and patents. Her research efforts have earned recognition including Technology Review’s "Top 100 Young Innovators,” Popular Science’s Brilliant 10, and the Dawson Biotechnology Award. She is President of the American Institute for Medical and Biological Engineering and is a fellow of AIMBE, IAMBE, CRS, and BMES. In 2015, she was elected to the National Academy of Medicine and in 2019 to the National Academy of Inventors.

Desai is a vocal advocate for STEM education and outreach to women and underrepresented minority students. She serves on the university’s Differences Matter Executive Committee and her work to break down institutional barriers to equity and cultivate a climate of inclusion was recognized by the AWIS Judith Poole Award and the UCSF Chancellors Award for the Advancement of Women. As president of AIMBE, she has led advocacy efforts for increased scientific funding and addressing workforce disparities in science/engineering. To foster the next generation of scientists, she has been involved in the SF Science Education partnership and has worked with outreach organizations such as the Lawrence Hall of Science, PBS, and the UN Women’s council to develop hand-on exhibits and videos related to nanotechnology and women in engineering.

She received her B.S. from Brown University in biomedical engineering in 1994 and was awarded a Ph.D. in bioengineering jointly from UCSF and UC Berkeley in 1998.

Research keywords

Nanostructured materials
Corneal
Bone
three dimensional scaffold and matrix fabrication
medical devices
bioengineering
Ocular
Retinal
implantable
drug delivery (Oral
surface modification and biocompatibility
BioMEMS and Biomedical Nanotechnology
cell encapsulation technologies (Pancreatic and Neurosecretory)
tissue engineering (Cardiovascular
nanotechnology
drug delivery systems
Polyesters
Drug Carriers
Nanostructures
Biocompatible Materials
Tissue Engineering
Calcium Phosphates
silicon
Delayed-Action Preparations
Surface Properties
Artificial Membranes
Microtechnology
Materials Testing
Nanoparticles

1.	Chancellor's Award for Diversity: Advancement of Women, UCSF, 2021
2.	President, Board of Directors, American Institute of Medical and Biological Engineering (AIMBE), 2020-2022
3.	Judith Pool Award, Association for Women in Science, Northern California Chapter, 2020
4.	Fellow, International Academy of Medical and Biological Engineering, 2019
5.	Fellow, National Academy of Inventors, 2019
6.	Chair, College of Fellows, American Insitute of Medical and Biological Engineering (AIMBE), 2018
7.	Deans Citation for Excellence in Teaching, UCSF, 2018
8.	Ernest L. Prien Endowed Professorship, UCSF, 2016
9.	Brown Engineering Alumni Medal (BEAM), Brown University School of Engineering, 2015
10.	Elected Member, National Academy of Medicine, (formerly Institute of Medicine), 2015
11.	AAUCSF 150th Anniversary Alumni Excellence Award, UCSF, 2015
12.	Biomaterial and Biointerfaces NIH Study Section, Appointed Chair, 2014
13.	Fellow, Biomedical Engineering Society (BMES), 2014
14.	McKinsey's 3rd Annual Women's Leadership Summit, Invited Participant, 2013
15.	OME Precision Medicine Summit, Invited Participant, 2013
16.	Featured Innovator, Scientific American, 2013
17.	Steering Committee, Whitaker International Scholars Programs, 2013
18.	Paul Dawson Biotechnology Award, American Association of Colleges of Pharmacy, 2012
19.	Elected Fellow of American Insitute of Medical and Biological Engineering (AIMBE), American Insitute of Medical and Biological Engineering (AIMBE), 2011
20.	Nanotechnology Judge, Siemens National Competition, 2011
21.	Translational Award Recipient, Wallace H. Coulter Foundation, 2011
22.	Review Committee, Whitaker International Scholars, 2011
23.	Standing Member, NIH Biomaterials and Biointerfaces Study Section, 2010
24.	Dean's Citation for Excellence in Teaching, University of California, San Francisco, 2010
25.	Awards for Best Papers (Oral and Pharmaceutical Categories), Controlled Release Society, 2009
26.	Senior Member, IEEE Society, 2009
27.	Work Cited, Nature Medicine's 5 Big Ideas for Nanotechnology, 2009
28.	National Judge, Siemens Math, Science, and Technology Competition, 2009
29.	San Francisco's Top 40 under 40, 7 x 7 Magazine, 2008
30.	Emerging Scholar Award, Diversity in Higher Education Journal, 2008
31.	Innovative Aspects of Oral Drug Delivery Award (Two Paper Awards), Capsugel/Pfizer, 2007
32.	Career Award, Engineering in Medicine and Biology Society (EMBS), 2007
33.	Faculty Leadership Collaborative, University of California, San Francisco, UCSF/CORO, 2007
34.	Rogers Bridging the Gap Award for New Technologies, 2006
35.	Grand Prize Award for Innovative Approaches to Drug Delivery, EURAND, 2006
36.	Distinguished Engineering Alumni Award, University of California, Berkeley, 2006
37.	Featured Exhibit, Women in Nanotechnology, Lawrence Hall of Science, 2005
38.	Judge in Nanotechnology, Siemens National Competition, 2005
39.	Nomination and Award, Women in Engineering Leadership Conference, 2005
40.	Innovative Aspects of Oral Drug Delivery Award (Paper Competition), Capsugel/Pfizer, 2004
41.	Woman of the Year, INDIA New England, 2004
42.	Winner of INDUS Top 15, INDUS, 2004
43.	Invited Participant: Keck Futures Initiative: Designing Nanostructure, National Academy of Engineering, 2004
44.	Award Finalist in Health and Medicine, World Technology Award, 2004
45.	Grand Prize Award for Outstanding Research in Oral Drug Delivery, EURAND, 2003
46.	Globus Indus Technovator Award, Massachusetts Institute of Technology, 2003
47.	"Brilliant 10" Top Scientists in the Nation, Popular Science, 2003
48.	Invited Conference Participant, Whitaker Leadership Conference, 2003
49.	Focused Giving Award, Johnson and Johnson, 2002
50.	Award for Contributions to Regenerative Medicine, McGowan Institute, 2002
51.	Visionary Science Award, BioMEMS and Nanotechnology Society, 2001
52.	Invited Participant, Frontiers in Engineering, National Academy of Engineering, 2001
53.	CAREER Award, National Science Foundation, 2000
54.	New Century Scholar Award, National Science Foundation, 2000
55.	Award of Distinction, University of Illinois, Chicago, College of Engineering, 2000
56.	Best Advisor Award, University of Illinois, Chicago, College of Engineering, 2000
57.	40 Under 40 Award: For Leadership and Innovation, Crain's Chicago Business, 1999
58.	MIT's TR100 Award, Technology Review Magazine's Top 100 Young Innovators, 1999
59.	Who's Who among America's Teachers, Crain's Chicago Business, 1998
60.	Graduate Conference Presentation Award, University of California, San Francisco, 1997
61.	Graduate Dissertation Research Award, University of California, San Francisco, 1997
62.	Graduate Students Association Travel Award, University of California, San Francisco, 1997
63.	Graduate Fellowship Recipient, National Science Foundation, 1995
64.	Graduate Fellowship in Biomedical Engineering, Whitaker Foundation, 1995
65.	Member, Sigma Xi, Scientific Honor Society, 1994
66.	Fellowship of the Regents, University of California, San Francisco, 1994

Publications

Peterson RJ, Reed RC, Zamecnik CR, Sallam MA, Finbloom JA, Martinez FJ, Levy JM, Moonwiriyakit A, Desai TA, Koval M. Apical integrins as a switchable target to regulate the epithelial barrier. J Cell Sci. 2024 Nov 18.

Cuylear DL, Fu ML, Chau JC, Bulkley D, Kharbikar B, Kazakia GJ, Jheon AH, Habelitz S, Kapila SD, Desai TA. Calcium phosphate nanoclusters modify periodontium remodeling and minimize orthodontic relapse. Biomaterials. 2024 Nov 14; 315:122965.

Grattoni A, Korbutt G, Tomei AA, García AJ, Pepper AR, Stabler C, Brehm M, Papas K, Citro A, Shirwan H, Millman JR, Melero-Martin J, Graham M, Sefton M, Ma M, Kenyon N, Veiseh O, Desai TA, Nostro MC, Marinac M, Sykes M, Russ HA, Odorico J, Tang Q, Ricordi C, Latres E, Mamrak NE, Giraldo J, Poznansky MC, de Vos P. Harnessing cellular therapeutics for type 1 diabetes mellitus: progress, challenges, and the road ahead. Nat Rev Endocrinol. 2024 Sep 03.

Cuylear DL, Fu ML, Chau JC, Kharbikar B, Kazakia GJ, Jheon A, Habelitz S, Kapila SD, Desai TA. Calcium phosphate nanoclusters modify periodontium remodeling and minimize orthodontic relapse. bioRxiv. 2024 Jul 30.

Hansen ME, Ibrahim Y, Desai TA, Koval M. Nanostructure-Mediated Transport of Therapeutics through Epithelial Barriers. Int J Mol Sci. 2024 Jun 28; 25(13).

Jana D, Han Z, Huang X, Wadhwa A, Raveendran A, Ebeid K, Meher N, Flavell RR, Desai T. Enhanced Prostate-specific Membrane Antigen Targeting by Precision Control of DNA Scaffolded Nanoparticle Ligand Presentation. ACS Nano. 2024 Jul 02; 18(26):16674-16683.

Subramaniam S, Akay M, Anastasio MA, Bailey V, Boas D, Bonato P, Chilkoti A, Cochran JR, Colvin V, Desai TA, Duncan JS, Epstein FH, Fraley S, Giachelli C, Grande-Allen KJ, Green J, Guo XE, Hilton IB, Humphrey JD, Johnson CR, Karniadakis G, King MR, Kirsch RF, Kumar S, Laurencin CT, Li S, Lieber RL, Lovell N, Mali P, Margulies SS, Meaney DF, Ogle B, Palsson B, A Peppas N, Perreault EJ, Rabbitt R, Setton LA, Shea LD, Shroff SG, Shung K, Tolias AS, van der Meulen MCH, Varghese S, Vunjak-Novakovic G, White JA, Winslow R, Zhang J, Zhang K, Zukoski C, Miller MI. Grand Challenges at the Interface of Engineering and Medicine. IEEE Open J Eng Med Biol. 2024; 5:1-13.

Mohindra P, Zhong JX, Fang Q, Cuylear DL, Huynh C, Qiu H, Gao D, Kharbikar BN, Huang X, Springer ML, Lee RJ, Desai TA. Local decorin delivery via hyaluronic acid microrods improves cardiac performance, ventricular remodeling after myocardial infarction. NPJ Regen Med. 2023 Oct 23; 8(1):60.

Hadley P, Chen Y, Cline L, Han Z, Tang Q, Huang X, Desai T. Precise surface functionalization of PLGA particles for human T cell modulation. Nat Protoc. 2023 Nov; 18(11):3289-3321.

Levy ES, Kim AS, Werlin E, Chen M, Sansbury BE, Spite M, Desai TA, Conte MS. Tissue factor targeting peptide enhances nanoparticle binding and delivery of a synthetic specialized pro-resolving lipid mediator to injured arteries. JVS Vasc Sci. 2023; 4:100126.

Desai T, Grattoni A. Robotic self-modulation enhances implantable long-acting drug delivery devices. Sci Robot. 2023 08 30; 8(81):eadj8292.

Cosgriff-Hernandez EM, Aguado BA, Akpa B, Fleming GC, Moore E, Porras AM, Boyle PM, Chan DD, Chesler N, Christman KL, Desai TA, Harley BAC, Hudalla GA, Killian ML, Maisel K, Maitland KC, Peyton SR, Pruitt BL, Stabenfeldt SE, Stevens KR, Bowden AK. Equitable hiring strategies towards a diversified faculty. Nat Biomed Eng. 2023 08; 7(8):961-968.

Nurunnabi M, Desai TA. Biomaterials for Oral Medicine. ACS Biomater Sci Eng. 2023 06 12; 9(6):2816-2818.

Rivera KO, Cuylear DL, Duke VR, O'Hara KM, Zhong JX, Elghazali NA, Finbloom JA, Kharbikar BN, Kryger AN, Miclau T, Marcucio RS, Bahney CS, Desai TA. Encapsulation of β-NGF in injectable microrods for localized delivery accelerates endochondral fracture repair. Front Bioeng Biotechnol. 2023; 11:1190371.

Chendke GS, Kharbikar BN, Ashe S, Faleo G, Sneddon JB, Tang Q, Hebrok M, Desai TA. Replenishable prevascularized cell encapsulation devices increase graft survival and function in the subcutaneous space. Bioeng Transl Med. 2023 Jul; 8(4):e10520.

Stevens KR, Desai TA. Centering Margins in Organ Assembly. Adv Biol (Weinh). 2023 05; 7(5):e2300146.

Bernards DA, Ma CJ, Zhang Y, Rodriguez TM, Dickson J, Kharbikar BN, Bhisitkul RB, Desai TA. Injectable Devices for Delivery of Liquid or Solid Protein Formulations. ACS Mater Au. 2023 May 10; 3(3):255-264.

Desai T, Mohindra P, Zhong J, Fang Q, Huynh C, Cuylear D, Qiu H, Gao D, Kharbikar B, Huang X, Springer M, Lee R. Local delivery of decorin via hyaluronic acid microrods improves cardiac performance and ventricular remodeling after myocardial infarction. Res Sq. 2023 Feb 08.

Finbloom JA, Raghavan P, Kwon M, Kharbikar BN, Yu MA, Desai TA. Codelivery of synergistic antimicrobials with polyelectrolyte nanocomplexes to treat bacterial biofilms and lung infections. Sci Adv. 2023 01 20; 9(3):eade8039.

Cuylear DL, Elghazali NA, Kapila SD, Desai TA. Calcium Phosphate Delivery Systems for Regeneration and Biomineralization of Mineralized Tissues of the Craniofacial Complex. Mol Pharm. 2023 02 06; 20(2):810-828.

Zhong JX, Raghavan P, Desai TA. Harnessing Biomaterials for Immunomodulatory-Driven Tissue Engineering. Regen Eng Transl Med. 2023; 9(2):224-239.

Murrow LM, Weber RJ, Caruso JA, McGinnis CS, Phong K, Gascard P, Rabadam G, Borowsky AD, Desai TA, Thomson M, Tlsty T, Gartner ZJ. Mapping hormone-regulated cell-cell interaction networks in the human breast at single-cell resolution. Cell Syst. 2022 08 17; 13(8):644-664.e8.

Kharbikar BN, Mohindra P, Desai TA. Biomaterials to enhance stem cell transplantation. Cell Stem Cell. 2022 05 05; 29(5):692-721.

Meher N, Seo K, Wang S, Bidkar AP, Fogarty M, Dhrona S, Huang X, Tang R, Blaha C, Evans MJ, Raleigh DR, Jun YW, VanBrocklin HF, Desai TA, Wilson DM, Ozawa T, Flavell RR. Synthesis and Preliminary Biological Assessment of Carborane-Loaded Theranostic Nanoparticles to Target Prostate-Specific Membrane Antigen. ACS Appl Mater Interfaces. 2021 Nov 24; 13(46):54739-54752.

Mofidfar M, Abdi B, Ahadian S, Mostafavi E, Desai TA, Abbasi F, Sun Y, Manche EE, Ta CN, Flowers CW. Drug delivery to the anterior segment of the eye: A review of current and future treatment strategies. Int J Pharm. 2021 Sep 25; 607:120924.

Kharbikar BN, Zhong JX, Cuylear DL, Perez CA, Desai TA. Theranostic biomaterials for tissue engineering. Curr Opin Biomed Eng. 2021 Sep; 19.

Dittloff KT, Iezzi A, Zhong JX, Mohindra P, Desai TA, Russell B. Transthyretin amyloid fibrils alter primary fibroblast structure, function, and inflammatory gene expression. Am J Physiol Heart Circ Physiol. 2021 07 01; 321(1):H149-H160.

Lykins WR, Hansen ME, Sun X, Advincula R, Finbloom JA, Jain AK, Zala Y, Ma A, Desai TA. Impact of Microdevice Geometry on Transit and Retention in the Murine Gastrointestinal Tract. ACS Biomater Sci Eng. 2023 06 12; 9(6):2891-2901.

Finbloom JA, Cao Y, Desai TA. Bioinspired Polymeric High Aspect Ratio Particles with Asymmetric Janus Functionalities. Adv Nanobiomed Res. 2021 May; 1(5).

Mohindra P, Desai TA. Micro- and nanoscale biophysical cues for cardiovascular disease therapy. Nanomedicine. 2021 06; 34:102365.

Levy ES, Chang R, Zamecnik CR, Dhariwala MO, Fong L, Desai TA. Multi-Immune Agonist Nanoparticle Therapy Stimulates Type I Interferons to Activate Antigen-Presenting Cells and Induce Antigen-Specific Antitumor Immunity. Mol Pharm. 2021 03 01; 18(3):1014-1025.

Stevens KR, Masters KS, Imoukhuede PI, Haynes KA, Setton LA, Cosgriff-Hernandez E, Lediju Bell MA, Rangamani P, Sakiyama-Elbert SE, Finley SD, Willits RK, Koppes AN, Chesler NC, Christman KL, Allen JB, Wong JY, El-Samad H, Desai TA, Eniola-Adefeso O. Fund Black scientists. Cell. 2021 02 04; 184(3):561-565.

Kharbikar BN, Chendke GS, Desai TA. Modulating the foreign body response of implants for diabetes treatment. Adv Drug Deliv Rev. 2021 07; 174:87-113.

Bowdish D, Desai TA, DePace A, Haswell ES, Baltrus D, García AJ, Deans T, Lage K, Wittkopp P. Leadership. Cell Syst. 2021 01 20; 12(1):1-4.

Rivera KO, Russo F, Boileau RM, Tomlinson RE, Miclau T, Marcucio RS, Desai TA, Bahney CS. Local injections of β-NGF accelerates endochondral fracture repair by promoting cartilage to bone conversion. Sci Rep. 2020 12 17; 10(1):22241.

Huang X, Williams JZ, Chang R, Li Z, Burnett CE, Hernandez-Lopez R, Setiady I, Gai E, Patterson DM, Yu W, Roybal KT, Lim WA, Desai TA. DNA scaffolds enable efficient and tunable functionalization of biomaterials for immune cell modulation. Nat Nanotechnol. 2021 02; 16(2):214-223.

Finbloom JA, Demaree B, Abate AR, Desai TA. Networks of High Aspect Ratio Particles to Direct Colloidal Assembly Dynamics and Cellular Interactions. Adv Funct Mater. 2020 Nov 25; 30(48).

Huang X, Shi X, Hansen ME, Setiady I, Nemeth CL, Celli A, Huang B, Mauro T, Koval M, Desai TA. Nanotopography Enhances Dynamic Remodeling of Tight Junction Proteins through Cytosolic Liquid Complexes. ACS Nano. 2020 10 27; 14(10):13192-13202.

Ahadian S, Finbloom JA, Mofidfar M, Diltemiz SE, Nasrollahi F, Davoodi E, Hosseini V, Mylonaki I, Sangabathuni S, Montazerian H, Fetah K, Nasiri R, Dokmeci MR, Stevens MM, Desai TA, Khademhosseini A. Micro and nanoscale technologies in oral drug delivery. Adv Drug Deliv Rev. 2020; 157:37-62.

Finbloom JA, Sousa F, Stevens MM, Desai TA. Engineering the drug carrier biointerface to overcome biological barriers to drug delivery. Adv Drug Deliv Rev. 2020 12; 167:89-108.

Cao Y, Desai TA. TiO2-Based Nanotopographical Cues Attenuate the Restenotic Phenotype in Primary Human Vascular Endothelial and Smooth Muscle Cells. ACS Biomater Sci Eng. 2020 02 10; 6(2):923-932.

Zamecnik CR, Levy ES, Lowe MM, Zirak B, Rosenblum MD, Desai TA. An Injectable Cytokine Trap for Local Treatment of Autoimmune Disease. Biomaterials. 2020 02; 230:119626.

Le LV, Chendke GS, Gamsey S, Wisniewski N, Desai TA. Near-Infrared Optical Nanosensors for Continuous Detection of Glucose. J Diabetes Sci Technol. 2020 03; 14(2):204-211.

Levy ES, Samy KE, Lamson NG, Whitehead KA, Kroetz DL, Desai TA. Reversible inhibition of efflux transporters by hydrogel microdevices. Eur J Pharm Biopharm. 2019 Dec; 145:76-84.

Chendke GS, Faleo G, Juang C, Parent AV, Bernards DA, Hebrok M, Tang Q, Desai TA. Supporting Survival of Transplanted Stem-Cell-Derived Insulin-Producing Cells in an Encapsulation Device Augmented with Controlled Release of Amino Acids. Adv Biosyst. 2019 Sep; 3(9).

Samy KE, Levy ES, Phong K, Demaree B, Abate AR, Desai TA. Human intestinal spheroids cultured using Sacrificial Micromolding as a model system for studying drug transport. Sci Rep. 2019 07 09; 9(1):9936.

Cao Y, Samy KE, Bernards DA, Desai TA. Recent advances in intraocular sustained-release drug delivery devices. Drug Discov Today. 2019 08; 24(8):1694-1700.

Nemeth CL, Lykins WR, Tran H, ElSayed MEH, Desai TA. Bottom-Up Fabrication of Multilayer Enteric Devices for the Oral Delivery of Peptides. Pharm Res. 2019 Apr 19; 36(6):89.

Le LV, Mkrtschjan MA, Russell B, Desai TA. Hang on tight: reprogramming the cell with microstructural cues. Biomed Microdevices. 2019 04 06; 21(2):43.

Samy KE, Cao Y, Kim J, Konichi da Silva NR, Phone A, Bloomer MM, Bhisitkul RB, Desai TA. Co-Delivery of Timolol and Brimonidine with a Polymer Thin-Film Intraocular Device. J Ocul Pharmacol Ther. 2019 03; 35(2):124-131.

Schlesinger EB, Bernards DA, Chen HH, Feindt J, Cao J, Dix D, Romano C, Bhisitkul RB, Desai TA. Device design methodology and formulation of a protein therapeutic for sustained release intraocular delivery. Bioeng Transl Med. 2019 Jan; 4(1):152-163.

Desai TA, Tang Q. Islet encapsulation therapy - racing towards the finish line? Nat Rev Endocrinol. 2018 11; 14(11):630-632.

Conte MS, Desai TA, Wu B, Schaller M, Werlin E. Pro-resolving lipid mediators in vascular disease. J Clin Invest. 2018 08 31; 128(9):3727-3735.

Wu B, Werlin EC, Chen M, Mottola G, Chatterjee A, Lance KD, Bernards DA, Sansbury BE, Spite M, Desai TA, Conte MS. Perivascular delivery of resolvin D1 inhibits neointimal hyperplasia in a rabbit vein graft model. J Vasc Surg. 2018 12; 68(6S):188S-200S.e4.

Willsey AJ, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA, Srivastava D, Davis GW, Doudna J, Chang E, Sohal V, Lowenstein DH, Li H, Agard D, Keiser MJ, Shoichet B, von Zastrow M, Mucke L, Finkbeiner S, Gan L, Sestan N, Ward ME, Huttenhain R, Nowakowski TJ, Bellen HJ, Frank LM, Khokha MK, Lifton RP, Kampmann M, Ideker T, State MW, Krogan NJ. The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders. Cell. 2018 07 26; 174(3):505-520.

Sneddon JB, Tang Q, Stock P, Bluestone JA, Roy S, Desai T, Hebrok M. Stem Cell Therapies for Treating Diabetes: Progress and Remaining Challenges. Cell Stem Cell. 2018 Jun 01; 22(6):810-823.

Urbano L, Clifton L, Ku HK, Kendall-Troughton H, Vandera KA, Matarese BFE, Abelha T, Li P, Desai T, Dreiss CA, Barker RD, Green MA, Dailey LA, Harvey RD. Influence of the Surfactant Structure on Photoluminescent π-Conjugated Polymer Nanoparticles: Interfacial Properties and Protein Binding. Langmuir. 2018 05 29; 34(21):6125-6137.

Le LV, Mohindra P, Fang Q, Sievers RE, Mkrtschjan MA, Solis C, Safranek CW, Russell B, Lee RJ, Desai TA. Injectable hyaluronic acid based microrods provide local micromechanical and biochemical cues to attenuate cardiac fibrosis after myocardial infarction. Biomaterials. 2018 07; 169:11-21.

Orive G, Emerich D, Khademhosseini A, Matsumoto S, Hernández RM, Pedraz JL, Desai T, Calafiore R, de Vos P. Engineering a Clinically Translatable Bioartificial Pancreas to Treat Type I Diabetes. Trends Biotechnol. 2018 04; 36(4):445-456.

Lykins WR, Luecke E, Johengen D, van der Straten A, Desai TA. Long acting systemic HIV pre-exposure prophylaxis: an examination of the field. Drug Deliv Transl Res. 2017 Dec; 7(6):805-816.

Mkrtschjan MA, Gaikwad SB, Kappenman KJ, Solís C, Dommaraju S, Le LV, Desai TA, Russell B. Lipid signaling affects primary fibroblast collective migration and anchorage in response to stiffness and microtopography. J Cell Physiol. 2018 04; 233(4):3672-3683.

Zamecnik CR, Lowe MM, Patterson DM, Rosenblum MD, Desai TA. Injectable Polymeric Cytokine-Binding Nanowires Are Effective Tissue-Specific Immunomodulators. ACS Nano. 2017 11 28; 11(11):11433-11440.

Kim J, Kudisch M, da Silva NRK, Asada H, Aya-Shibuya E, Bloomer MM, Mudumba S, Bhisitkul RB, Desai TA. Long-term intraocular pressure reduction with intracameral polycaprolactone glaucoma devices that deliver a novel anti-glaucoma agent. J Control Release. 2018 01 10; 269:45-51.

Chang R, Faleo G, Russ HA, Parent AV, Elledge SK, Bernards DA, Allen JL, Villanueva K, Hebrok M, Tang Q, Desai TA. Nanoporous Immunoprotective Device for Stem-Cell-Derived β-Cell Replacement Therapy. ACS Nano. 2017 08 22; 11(8):7747-7757.

Nuhn H, Blanco CE, Desai TA. Nanoengineered Stent Surface to Reduce In-Stent Restenosis in Vivo. ACS Appl Mater Interfaces. 2017 Jun 14; 9(23):19677-19686.

Desai T, Shea LD. Advances in islet encapsulation technologies. Nat Rev Drug Discov. 2017 04 28; 16(5):367.

Song S, Yeung R, Park J, Posselt AM, Desai TA, Tang Q, Roy S. Glucose-Stimulated Insulin Response of Silicon Nanopore-Immunoprotected Islets under Convective Transport. ACS Biomater Sci Eng. 2017 Jun 12; 3(6):1051-1061.

Stewart T, Koval WT, Molina SA, Bock SM, Lillard JW, Ross RF, Desai TA, Koval M. Calibrated flux measurements reveal a nanostructure-stimulated transcytotic pathway. Exp Cell Res. 2017 06 15; 355(2):153-161.

Weber RJ, Desai TA, Gartner ZJ. Non-autonomous cell proliferation in the mammary gland and cancer. Curr Opin Cell Biol. 2017 04; 45:55-61.

Fox CB, Nemeth CL, Chevalier RW, Cantlon J, Bogdanoff DB, Hsiao JC, Desai TA. Picoliter-volume inkjet printing into planar microdevice reservoirs for low-waste, high-capacity drug loading. Bioeng Transl Med. 2017 Mar; 2(1):9-16.

Desai T, Shea LD. Advances in islet encapsulation technologies. Nat Rev Drug Discov. 2017 May; 16(5):338-350.

Lance KD, Bernards DA, Ciaccio NA, Good SD, Mendes TS, Kudisch M, Chan E, Ishikiriyama M, Bhisitkul RB, Desai TA. In vivo and in vitro sustained release of ranibizumab from a nanoporous thin-film device. Drug Deliv Transl Res. 2016 12; 6(6):771-780.

Weber RJ, Cerchiari AE, Delannoy LS, Garbe JC, LaBarge MA, Desai TA, Gartner ZJ. Rapid Organoid Reconstitution by Chemical Micromolding. ACS Biomater Sci Eng. 2016 Nov 14; 2(11):1851-1855.

Cerchiari AE, Samy KE, Todhunter ME, Schlesinger E, Henise J, Rieken C, Gartner ZJ, Desai TA. Probing the luminal microenvironment of reconstituted epithelial microtissues. Sci Rep. 2016 09 13; 6:33148.

Lance KD, Chatterjee A, Wu B, Mottola G, Nuhn H, Lee PP, Sansbury BE, Spite M, Desai TA, Conte MS. Unidirectional and sustained delivery of the proresolving lipid mediator resolvin D1 from a biodegradable thin film device. J Biomed Mater Res A. 2017 01; 105(1):31-41.

Kim J, Kudisch M, Mudumba S, Asada H, Aya-Shibuya E, Bhisitkul RB, Desai TA. Biocompatibility and Pharmacokinetic Analysis of an Intracameral Polycaprolactone Drug Delivery Implant for Glaucoma. Invest Ophthalmol Vis Sci. 2016 08 01; 57(10):4341-6.

Fox CB, Cao Y, Nemeth CL, Chirra HD, Chevalier RW, Xu AM, Melosh NA, Desai TA. Fabrication of Sealed Nanostraw Microdevices for Oral Drug Delivery. ACS Nano. 2016 06 28; 10(6):5873-81.

Huebsch N, Loskill P, Deveshwar N, Spencer CI, Judge LM, Mandegar MA, Fox CB, Mohamed TM, Ma Z, Mathur A, Sheehan AM, Truong A, Saxton M, Yoo J, Srivastava D, Desai TA, So PL, Healy KE, Conklin BR. Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses. Sci Rep. 2016 Apr 20; 6:24726.

Wu B, Mottola G, Chatterjee A, Lance KD, Chen M, Siguenza IO, Desai TA, Conte MS. Perivascular delivery of resolvin D1 inhibits neointimal hyperplasia in a rat model of arterial injury. J Vasc Surg. 2017 Jan; 65(1):207-217.e3.

Song S, Faleo G, Yeung R, Kant R, Posselt AM, Desai TA, Tang Q, Roy S. Silicon nanopore membrane (SNM) for islet encapsulation and immunoisolation under convective transport. Sci Rep. 2016 Mar 24; 6:23679.

Schlesinger E, Johengen D, Luecke E, Rothrock G, McGowan I, van der Straten A, Desai T. A Tunable, Biodegradable, Thin-Film Polymer Device as a Long-Acting Implant Delivering Tenofovir Alafenamide Fumarate for HIV Pre-exposure Prophylaxis. Pharm Res. 2016 Jul; 33(7):1649-56.

Tang Q, Desai TA. Approaching a cure for type 1 diabetes. Nat Med. 2016 Mar; 22(3):236-7.

Lee PP, Desai TA. Nitinol-Based Nanotubular Arrays with Controlled Diameters Upregulate Human Vascular Cell ECM Production. ACS Biomater Sci Eng. 2016 Mar 14; 2(3):409-414.

Allen J, Ryu J, Maggi A, Flores B, Greer JR, Desai T. Tunable Microfibers Suppress Fibrotic Encapsulation via Inhibition of TGFβ Signaling. Tissue Eng Part A. 2016 Jan; 22(1-2):142-50.

Lance KD, Good SD, Mendes TS, Ishikiriyama M, Chew P, Estes LS, Yamada K, Mudumba S, Bhisitkul RB, Desai TA. In Vitro and In Vivo Sustained Zero-Order Delivery of Rapamycin (Sirolimus) From a Biodegradable Intraocular Device. Invest Ophthalmol Vis Sci. 2015 Nov; 56(12):7331-7.

Walsh LA, Allen JL, Desai TA. Nanotopography applications in drug delivery. Expert Opin Drug Deliv. 2015; 12(12):1823-7.

Todhunter ME, Jee NY, Hughes AJ, Coyle MC, Cerchiari A, Farlow J, Garbe JC, LaBarge MA, Desai TA, Gartner ZJ. Programmed synthesis of three-dimensional tissues. Nat Methods. 2015 Oct; 12(10):975-81.

Fox CB, Kim J, Le LV, Nemeth CL, Chirra HD, Desai TA. Micro/nanofabricated platforms for oral drug delivery. J Control Release. 2015 Dec 10; 219:431-444.

Schlesinger E, Ciaccio N, Desai TA. Polycaprolactone thin-film drug delivery systems: Empirical and predictive models for device design. Mater Sci Eng C Mater Biol Appl. 2015 Dec 01; 57:232-9.

Nyitray CE, Chang R, Faleo G, Lance KD, Bernards DA, Tang Q, Desai TA. Polycaprolactone Thin-Film Micro- and Nanoporous Cell-Encapsulation Devices. ACS Nano. 2015 Jun 23; 9(6):5675-82.

Walsh L, Ryu J, Bock S, Koval M, Mauro T, Ross R, Desai T. Nanotopography facilitates in vivo transdermal delivery of high molecular weight therapeutics through an integrin-dependent mechanism. Nano Lett. 2015 Apr 08; 15(4):2434-41.

Simovic S, Song Y, Nann T, Desai TA. Intestinal absorption of fluorescently labeled nanoparticles. Nanomedicine. 2015 Jul; 11(5):1169-78.

Fox CB, Kim J, Schlesinger EB, Chirra HD, Desai TA. Fabrication of micropatterned polymeric nanowire arrays for high-resolution reagent localization and topographical cellular control. Nano Lett. 2015 Mar 11; 15(3):1540-6.

Cerchiari AE, Garbe JC, Jee NY, Todhunter ME, Broaders KE, Peehl DM, Desai TA, LaBarge MA, Thomson M, Gartner ZJ. A strategy for tissue self-organization that is robust to cellular heterogeneity and plasticity. Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7):2287-92.

Peña JR, Pinney JR, Ayala P, Desai TA, Goldspink PH. Localized delivery of mechano-growth factor E-domain peptide via polymeric microstructures improves cardiac function following myocardial infarction. Biomaterials. 2015 Apr; 46:26-34.

Kim J, Schlesinger EB, Desai TA. Nanostructured materials for ocular delivery: nanodesign for enhanced bioadhesion, transepithelial permeability and sustained delivery. Ther Deliv. 2015; 6(12):1365-76.

Cerchiari A, Garbe JC, Todhunter ME, Jee NY, Pinney JR, LaBarge MA, Desai TA, Gartner ZJ. Formation of spatially and geometrically controlled three-dimensional tissues in soft gels by sacrificial micromolding. Tissue Eng Part C Methods. 2015 Jun; 21(6):541-7.

Weber RJ, Liang SI, Selden NS, Desai TA, Gartner ZJ. Efficient targeting of fatty-acid modified oligonucleotides to live cell membranes through stepwise assembly. Biomacromolecules. 2014 Dec 08; 15(12):4621-6.

Doroudian G, Pinney J, Ayala P, Los T, Desai TA, Russell B. Sustained delivery of MGF peptide from microrods attracts stem cells and reduces apoptosis of myocytes. Biomed Microdevices. 2014 Oct; 16(5):705-15.

Silvestrini MT, Yin D, Martin AJ, Coppes VG, Mann P, Larson PS, Starr PA, Zeng X, Gupta N, Panter SS, Desai TA, Lim DA. Interventional magnetic resonance imaging-guided cell transplantation into the brain with radially branched deployment. Mol Ther. 2015 Jan; 23(1):119-29.

Lee PP, Cerchiari A, Desai TA. Nitinol-based nanotubular coatings for the modulation of human vascular cell function. Nano Lett. 2014 Sep 10; 14(9):5021-8.

Uskokovic V, Desai TA. Nanoparticulate drug delivery platforms for advancing bone infection therapies. Expert Opin Drug Deliv. 2014 Dec; 11(12):1899-912.

Wade JS, Desai TA. Planar microdevices enhance transport of large molecular weight molecules across retinal pigment epithelial cells. Biomed Microdevices. 2014 Aug; 16(4):629-38.

Pinney JR, Melkus G, Cerchiari A, Hawkins J, Desai TA. Novel functionalization of discrete polymeric biomaterial microstructures for applications in imaging and three-dimensional manipulation. ACS Appl Mater Interfaces. 2014 Aug 27; 6(16):14477-85.

Uskokovic V, Desai TA. Does translational symmetry matter on the micro scale? Fibroblastic and osteoblastic interactions with the topographically distinct poly(ε-caprolactone)/hydroxyapatite thin films. ACS Appl Mater Interfaces. 2014 Aug 13; 6(15):13209-20.

Pinney JR, Du KT, Ayala P, Fang Q, Sievers RE, Chew P, Delrosario L, Lee RJ, Desai TA. Discrete microstructural cues for the attenuation of fibrosis following myocardial infarction. Biomaterials. 2014 Oct; 35(31):8820-8828.

Muthusubramaniam L, Zaitseva T, Paukshto M, Martin G, Desai T. Effect of collagen nanotopography on keloid fibroblast proliferation and matrix synthesis: implications for dermal wound healing. Tissue Eng Part A. 2014 Oct; 20(19-20):2728-36.

Chirra HD, Shao L, Ciaccio N, Fox CB, Wade JM, Ma A, Desai TA. Planar microdevices for enhanced in vivo retention and oral bioavailability of poorly permeable drugs. Adv Healthc Mater. 2014 Oct; 3(10):1648-54.

Schweicher J, Desai TA. Facile Synthesis of Robust Free-Standing TiO2 Nanotubular Membranes for Biofiltration Applications. J Appl Electrochem. 2014 Mar 01; 44(3):411-418.

Nyitray CE, Chavez MG, Desai TA. Compliant 3D microenvironment improves β-cell cluster insulin expression through mechanosensing and β-catenin signaling. Tissue Eng Part A. 2014 Jul; 20(13-14):1888-95.

Uskokovic V, Desai TA. Simultaneous bactericidal and osteogenic effect of nanoparticulate calcium phosphate powders loaded with clindamycin on osteoblasts infected with Staphylococcus aureus. Mater Sci Eng C Mater Biol Appl. 2014 Apr 01; 37:210-22.

Kurpinski K, Johnson T, Kumar S, Desai T, Li S. Mastering translational medicine: interdisciplinary education for a new generation. Sci Transl Med. 2014 Jan 08; 6(218):218fs2.

Calvert KL, Desai T, Webster TJ. Advances in calcium phosphate coatings--anodic spark deposition: a review. Front Biosci (Landmark Ed). 2014 01 01; 19(3):475-89.

Schweicher J, Nyitray C, Desai TA. Membranes to achieve immunoprotection of transplanted islets. Front Biosci (Landmark Ed). 2014 01 01; 19(1):49-76.

Fox CB, Chirra HD, Desai TA. Planar bioadhesive microdevices: a new technology for oral drug delivery. Curr Pharm Biotechnol. 2014; 15(7):673-83.

Uskokovic V, Desai TA. In vitro analysis of nanoparticulate hydroxyapatite/chitosan composites as potential drug delivery platforms for the sustained release of antibiotics in the treatment of osteomyelitis. J Pharm Sci. 2014 Feb; 103(2):567-79.

Kam KR, Walsh LA, Bock SM, Ollerenshaw JD, Ross RF, Desai TA. The effect of nanotopography on modulating protein adsorption and the fibrotic response. Tissue Eng Part A. 2014 Jan; 20(1-2):130-8.

Desai TA, Uskokovic V. Calcium phosphate nanoparticles: a future therapeutic platform for the treatment of osteomyelitis? Ther Deliv. 2013 Jun; 4(6):643-5.

Uskokovic V, Hoover C, Vukomanovic M, Uskokovic DP, Desai TA. Osteogenic and antimicrobial nanoparticulate calcium phosphate and poly-(D,L-lactide-co-glycolide) powders for the treatment of osteomyelitis. Mater Sci Eng C Mater Biol Appl. 2013 Aug 01; 33(6):3362-73.

Uskokovic V, Batarni SS, Schweicher J, King A, Desai TA. Effect of calcium phosphate particle shape and size on their antibacterial and osteogenic activity in the delivery of antibiotics in vitro. ACS Appl Mater Interfaces. 2013 Apr 10; 5(7):2422-31.

Koulajian K, Desai T, Liu GC, Ivovic A, Patterson JN, Tang C, El-Benna J, Joseph JW, Scholey JW, Giacca A. NADPH oxidase inhibition prevents beta cell dysfunction induced by prolonged elevation of oleate in rodents. Diabetologia. 2013 May; 56(5):1078-87.

Bernards DA, Bhisitkul RB, Wynn P, Steedman MR, Lee OT, Wong F, Thoongsuwan S, Desai TA. Ocular biocompatibility and structural integrity of micro- and nanostructured poly(caprolactone) films. J Ocul Pharmacol Ther. 2013 Mar; 29(2):249-57.

Silvestrini MT, Yin D, Coppes VG, Mann P, Martin AJ, Larson PS, Starr PA, Gupta N, Panter SS, Desai TA, Lim DA. Radially branched deployment for more efficient cell transplantation at the scale of the human brain. Stereotact Funct Neurosurg. 2013; 91(2):92-103.

Kam KR, Desai TA. Nano- and microfabrication for overcoming drug delivery challenges. J Mater Chem B. 2013; 1(14):1878-1884.

Kam KR, Walsh LA, Bock SM, Koval M, Fischer KE, Ross RF, Desai TA. Nanostructure-mediated transport of biologics across epithelial tissue: enhancing permeability via nanotopography. Nano Lett. 2013 Jan 09; 13(1):164-71.

Desai T. In the spotlight: Tissue engineering. IEEE Rev Biomed Eng. 2013; 6:27-8.

Uskokovic V, Desai TA. Phase composition control of calcium phosphate nanoparticles for tunable drug delivery kinetics and treatment of osteomyelitis. I. Preparation and drug release. J Biomed Mater Res A. 2013 May; 101(5):1416-26.

Uskokovic V, Desai TA. Phase composition control of calcium phosphate nanoparticles for tunable drug delivery kinetics and treatment of osteomyelitis. II. Antibacterial and osteoblastic response. J Biomed Mater Res A. 2013 May; 101(5):1427-36.

Bernards DA, Lance KD, Ciaccio NA, Desai TA. Nanostructured thin film polymer devices for constant-rate protein delivery. Nano Lett. 2012 Oct 10; 12(10):5355-61.

Chirra HD, Desai TA. Multi-reservoir bioadhesive microdevices for independent rate-controlled delivery of multiple drugs. Small. 2012 Dec 21; 8(24):3839-46.

Chirra HD, Desai TA. Emerging microtechnologies for the development of oral drug delivery devices. Adv Drug Deliv Rev. 2012 Nov; 64(14):1569-78.

Uskokovic V, Lee K, Lee PP, Fischer KE, Desai TA. Shape effect in the design of nanowire-coated microparticles as transepithelial drug delivery devices. ACS Nano. 2012 Sep 25; 6(9):7832-41.

Chavez MG, Yu W, Biehs B, Harada H, Snead ML, Lee JS, Desai TA, Klein OD. Characterization of dental epithelial stem cells from the mouse incisor with two-dimensional and three-dimensional platforms. Tissue Eng Part C Methods. 2013 Jan; 19(1):15-24.

Mendelsohn AD, Nyitray C, Sena M, Desai TA. Size-controlled insulin-secreting cell clusters. Acta Biomater. 2012 Dec; 8(12):4278-84.

Crawford C, Kennedy-Lydon T, Sprott C, Desai T, Sawbridge L, Munday J, Unwin RJ, Wildman SS, Peppiatt-Wildman CM. An intact kidney slice model to investigate vasa recta properties and function in situ. Nephron Physiol. 2012; 120(3):p17-31.

Horst OV, Chavez MG, Jheon AH, Desai T, Klein OD. Stem cell and biomaterials research in dental tissue engineering and regeneration. Dent Clin North Am. 2012 Jul; 56(3):495-520.

Tucker RM, Parcher BW, Jones EF, Desai TA. Single-injection HPLC method for rapid analysis of a combination drug delivery system. AAPS PharmSciTech. 2012 Jun; 13(2):605-10.

Curtis MW, Budyn E, Desai TA, Samarel AM, Russell B. Microdomain heterogeneity in 3D affects the mechanics of neonatal cardiac myocyte contraction. Biomech Model Mechanobiol. 2013 Jan; 12(1):95-109.

Tang C, Koulajian K, Schuiki I, Zhang L, Desai T, Ivovic A, Wang P, Robson-Doucette C, Wheeler MB, Minassian B, Volchuk A, Giacca A. Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic reticulum stress. Diabetologia. 2012 May; 55(5):1366-79.

Armitage B, Desai T, Jiang S, Whitten D. Preface for the Bioinspired Assemblies and Interfaces Special Issue. Langmuir. 2012 Jan 31; 28(4):1943.

Minami SS, Sun B, Popat K, Kauppinen T, Pleiss M, Zhou Y, Ward ME, Floreancig P, Mucke L, Desai T, Gan L. Selective targeting of microglia by quantum dots. J Neuroinflammation. 2012 Jan 24; 9:22.

Muthusubramaniam L, Peng L, Zaitseva T, Paukshto M, Martin GR, Desai TA. Collagen fibril diameter and alignment promote the quiescent keratocyte phenotype. J Biomed Mater Res A. 2012 Mar; 100(3):613-21.

Uskokovic V, Lee PP, Walsh LA, Fischer KE, Desai TA. PEGylated silicon nanowire coated silica microparticles for drug delivery across intestinal epithelium. Biomaterials. 2012 Feb; 33(5):1663-72.

Roy S, Goldman K, Marchant R, Zydney A, Brown D, Fleischman A, Conlisk A, Desai T, Duffy S, Humes H, Fissell W. Implanted renal replacement for end-stage renal disease. Panminerva Med. 2011 Sep; 53(3):155-66.

Patel AA, Desai TA, Kumar S. Microtopographical assembly of cardiomyocytes. Integr Biol (Camb). 2011 Oct; 3(10):1011-9.

Ayala P, Desai TA. Integrin α3 blockade enhances microtopographical down-regulation of α-smooth muscle actin: role of microtopography in ECM regulation. Integr Biol (Camb). 2011 Jul; 3(7):733-41.

Van Hoof D, Mendelsohn AD, Seerke R, Desai TA, German MS. Differentiation of human embryonic stem cells into pancreatic endoderm in patterned size-controlled clusters. Stem Cell Res. 2011 May; 6(3):276-85.

Fischer KE, Nagaraj G, Hugh Daniels R, Li E, Cowles VE, Miller JL, Bunger MD, Desai TA. Hierarchical nanoengineered surfaces for enhanced cytoadhesion and drug delivery. Biomaterials. 2011 May; 32(13):3499-506.

Muthusubramaniam L, Lowe R, Fissell WH, Li L, Marchant RE, Desai TA, Roy S. Hemocompatibility of silicon-based substrates for biomedical implant applications. Ann Biomed Eng. 2011 Apr; 39(4):1296-305.

Fischer KE, Jayagopal A, Nagaraj G, Daniels RH, Li EM, Silvestrini MT, Desai TA. Nanoengineered surfaces enhance drug loading and adhesion. Nano Lett. 2011 Mar 09; 11(3):1076-81.

Desai T. In the spotlight: tissue engineering--translation for tissue engineering and regenerative medicine. IEEE Rev Biomed Eng. 2011; 4:24-5.

Curtis MW, Sharma S, Desai TA, Russell B. Hypertrophy, gene expression, and beating of neonatal cardiac myocytes are affected by microdomain heterogeneity in 3D. Biomed Microdevices. 2010 Dec; 12(6):1073-85.

Saldanha KJ, Doan RP, Ainslie KM, Desai TA, Majumdar S. Micrometer-sized iron oxide particle labeling of mesenchymal stem cells for magnetic resonance imaging-based monitoring of cartilage tissue engineering. Magn Reson Imaging. 2011 Jan; 29(1):40-9.

Ayala P, Lopez JI, Desai TA. Microtopographical cues in 3D attenuate fibrotic phenotype and extracellular matrix deposition: implications for tissue regeneration. Tissue Eng Part A. 2010 Aug; 16(8):2519-27.

Mendelsohn AD, Bernards DA, Lowe RD, Desai TA. Patterning of mono- and multilayered pancreatic beta-cell clusters. Langmuir. 2010 Jun 15; 26(12):9943-9.

Bernards DA, Desai TA. Nanotemplating of biodegradable polymer membranes for constant-rate drug delivery. Adv Mater. 2010 Jun 04; 22(21):2358-62.

Steedman MR, Tao SL, Klassen H, Desai TA. Enhanced differentiation of retinal progenitor cells using microfabricated topographical cues. Biomed Microdevices. 2010 Jun; 12(3):363-9.

Patel AA, Thakar RG, Chown M, Ayala P, Desai TA, Kumar S. Biophysical mechanisms of single-cell interactions with microtopographical cues. Biomed Microdevices. 2010 Apr; 12(2):287-96.

Collins JM, Ayala P, Desai TA, Russell B. Three-dimensional culture with stiff microstructures increases proliferation and slows osteogenic differentiation of human mesenchymal stem cells. Small. 2010 Feb 05; 6(3):355-60.

Desai TA. In the spotlight: tissue engineering. IEEE Rev Biomed Eng. 2010; 3:23-4.

Mendelsohn A, Desai T. Inorganic nanoporous membranes for immunoisolated cell-based drug delivery. Adv Exp Med Biol. 2010; 670:104-25.

Bernards DA, Desai TA. Nanoscale porosity in polymer films: fabrication and therapeutic applications. Soft Matter. 2010 Jan 01; 6(8):1621-1631.

Peng L, Barczak AJ, Barbeau RA, Xiao Y, LaTempa TJ, Grimes CA, Desai TA. Whole genome expression analysis reveals differential effects of TiO2 nanotubes on vascular cells. Nano Lett. 2010 Jan; 10(1):143-8.

Ainslie KM, Tao SL, Popat KC, Daniels H, Hardev V, Grimes CA, Desai TA. In vitro inflammatory response of nanostructured titania, silicon oxide, and polycaprolactone. J Biomed Mater Res A. 2009 Dec; 91(3):647-55.

Ainslie KM, Lowe RD, Beaudette TT, Petty L, Bachelder EM, Desai TA. Microfabricated devices for enhanced bioadhesive drug delivery: attachment to and small-molecule release through a cell monolayer under flow. Small. 2009 Dec; 5(24):2857-63.

Biehl JK, Yamanaka S, Desai TA, Boheler KR, Russell B. Proliferation of mouse embryonic stem cell progeny and the spontaneous contractile activity of cardiomyocytes are affected by microtopography. Dev Dyn. 2009 Aug; 238(8):1964-73.

Peng L, Mendelsohn AD, LaTempa TJ, Yoriya S, Grimes CA, Desai TA. Long-term small molecule and protein elution from TiO2 nanotubes. Nano Lett. 2009 May; 9(5):1932-6.

Fischer KE, Alemán BJ, Tao SL, Hugh Daniels R, Li EM, Bünger MD, Nagaraj G, Singh P, Zettl A, Desai TA. Biomimetic nanowire coatings for next generation adhesive drug delivery systems. Nano Lett. 2009 Feb; 9(2):716-20.

Desai TA. In the spotlight: tissue engineering--quantitative analysis of complex 3-D tissues. IEEE Rev Biomed Eng. 2009; 2:21-2.

Peng L, Eltgroth ML, LaTempa TJ, Grimes CA, Desai TA. The effect of TiO2 nanotubes on endothelial function and smooth muscle proliferation. Biomaterials. 2009 Mar; 30(7):1268-72.

Ainslie KM, Desai TA. Microfabricated implants for applications in therapeutic delivery, tissue engineering, and biosensing. Lab Chip. 2008 Nov; 8(11):1864-78.

Thakar RG, Chown MG, Patel A, Peng L, Kumar S, Desai TA. Contractility-dependent modulation of cell proliferation and adhesion by microscale topographical cues. Small. 2008 Sep; 4(9):1416-24.

Pattani VP, Li C, Desai TA, Vu TQ. Microcontact printing of quantum dot bioconjugate arrays for localized capture and detection of biomolecules. Biomed Microdevices. 2008 Jun; 10(3):367-74.

Redenti S, Tao S, Yang J, Gu P, Klassen H, Saigal S, Desai T, Young MJ. Retinal tissue engineering using mouse retinal progenitor cells and a novel biodegradable, thin-film poly(e-caprolactone) nanowire scaffold. J Ocul Biol Dis Infor. 2008 Mar; 1(1):19-29.

Ainslie KM, Kraning CM, Desai TA. Microfabrication of an asymmetric, multi-layered microdevice for controlled release of orally delivered therapeutics. Lab Chip. 2008 Jul; 8(7):1042-7.

Ainslie KM, Tao SL, Popat KC, Desai TA. In vitro immunogenicity of silicon-based micro- and nanostructured surfaces. ACS Nano. 2008 May; 2(5):1076-84.

Norman JJ, Collins JM, Sharma S, Russell B, Desai TA. Microstructures in 3D biological gels affect cell proliferation. Tissue Eng Part A. 2008 Mar; 14(3):379-90.

Nehilla BJ, Allen PG, Desai TA. Surfactant-free, drug-quantum-dot coloaded poly(lactide-co-glycolide) nanoparticles: towards multifunctional nanoparticles. ACS Nano. 2008 Mar; 2(3):538-44.

Tao SL, Popat KC, Norman JJ, Desai TA. Surface modification of SU-8 for enhanced biofunctionality and nonfouling properties. Langmuir. 2008 Mar 18; 24(6):2631-6.

Houtchens GR, Foster MD, Desai TA, Morgan EF, Wong JY. Combined effects of microtopography and cyclic strain on vascular smooth muscle cell orientation. J Biomech. 2008; 41(4):762-9.

Sarkar S, Isenberg BC, Hodis E, Leach JB, Desai TA, Wong JY. Fabrication of a layered microstructured polycaprolactone construct for 3-D tissue engineering. J Biomater Sci Polym Ed. 2008; 19(10):1347-62.

Desai TA. In the Spotlight: Tissue and Molecular Engineering. IEEE Rev Biomed Eng. 2008; 1:21-2.

Popat KC, Eltgroth M, LaTempa TJ, Grimes CA, Desai TA. Titania nanotubes: a novel platform for drug-eluting coatings for medical implants? Small. 2007 Nov; 3(11):1878-81.

Neeley WL, Redenti S, Klassen H, Tao S, Desai T, Young MJ, Langer R. A microfabricated scaffold for retinal progenitor cell grafting. Biomaterials. 2008 Feb; 29(4):418-26.

Popat KC, Eltgroth M, Latempa TJ, Grimes CA, Desai TA. Decreased Staphylococcus epidermis adhesion and increased osteoblast functionality on antibiotic-loaded titania nanotubes. Biomaterials. 2007 Nov; 28(32):4880-8.

Nehilla BJ, Bergkvist M, Popat KC, Desai TA. Purified and surfactant-free coenzyme Q10-loaded biodegradable nanoparticles. Int J Pharm. 2008 Feb 04; 348(1-2):107-14.

Tao SL, Desai TA. Aligned arrays of biodegradable poly(epsilon-caprolactone) nanowires and nanofibers by template synthesis. Nano Lett. 2007 Jun; 7(6):1463-8.

Tan W, Vinegoni C, Norman JJ, Desai TA, Boppart SA. Imaging cellular responses to mechanical stimuli within three-dimensional tissue constructs. Microsc Res Tech. 2007 Apr; 70(4):361-71.

Tao S, Young C, Redenti S, Zhang Y, Klassen H, Desai T, Young MJ. Survival, migration and differentiation of retinal progenitor cells transplanted on micro-machined poly(methyl methacrylate) scaffolds to the subretinal space. Lab Chip. 2007 Jun; 7(6):695-701.

Popat KC, Leoni L, Grimes CA, Desai TA. Influence of engineered titania nanotubular surfaces on bone cells. Biomaterials. 2007 Jul; 28(21):3188-97.

Popat KC, Chatvanichkul KI, Barnes GL, Latempa TJ, Grimes CA, Desai TA. Osteogenic differentiation of marrow stromal cells cultured on nanoporous alumina surfaces. J Biomed Mater Res A. 2007 Mar 15; 80(4):955-64.

La Flamme KE, Popat KC, Leoni L, Markiewicz E, La Tempa TJ, Roman BB, Grimes CA, Desai TA. Biocompatibility of nanoporous alumina membranes for immunoisolation. Biomaterials. 2007 Jun; 28(16):2638-45.

La Flamme KE, LaTempa TJ, Grimes CA, Desai TA. The effects of cell density and device arrangement on the behavior of macroencapsulated beta-cells. Cell Transplant. 2007; 16(8):765-74.

Tan W, Oldenburg AL, Norman JJ, Desai TA, Boppart SA. Optical coherence tomography of cell dynamics in three-dimensional tissue models. Opt Express. 2006 Aug 07; 14(16):7159-71.

Sarkar S, Lee GY, Wong JY, Desai TA. Development and characterization of a porous micro-patterned scaffold for vascular tissue engineering applications. Biomaterials. 2006 Sep; 27(27):4775-82.

Popat KC, Daniels RH, Dubrow RS, Hardev V, Desai TA. Nanostructured surfaces for bone biotemplating applications. J Orthop Res. 2006 Apr; 24(4):619-27.

Ohno S, Schmid T, Tanne Y, Kamiya T, Honda K, Ohno-Nakahara M, Swentko N, Desai TA, Tanne K, Knudson CB, Knudson W. Expression of superficial zone protein in mandibular condyle cartilage. Osteoarthritis Cartilage. 2006 Aug; 14(8):807-13.

Norman JJ, Desai TA. Methods for fabrication of nanoscale topography for tissue engineering scaffolds. Ann Biomed Eng. 2006 Jan; 34(1):89-101.

Lopez CA, Fleischman AJ, Roy S, Desai TA. Evaluation of silicon nanoporous membranes and ECM-based microenvironments on neurosecretory cells. Biomaterials. 2006 Jun; 27(16):3075-83.

Saltzman M, Desai T. Drug delivery in the BME curricula. Ann Biomed Eng. 2006 Feb; 34(2):270-5.

Nayak NR, Kuo CJ, Desai TA, Wiegand SJ, Lasley BL, Giudice LC, Brenner RM. Expression, localization and hormonal control of angiopoietin-1 in the rhesus macaque endometrium: potential role in spiral artery growth. Mol Hum Reprod. 2005 Nov; 11(11):791-9.

Gimi B, Leoni L, Oberholzer J, Braun M, Avila J, Wang Y, Desai T, Philipson LH, Magin RL, Roman BB. Functional MR microimaging of pancreatic beta-cell activation. Cell Transplant. 2006; 15(2):195-203.

Tao SL, Popat K, Desai TA. Off-wafer fabrication and surface modification of asymmetric 3D SU-8 microparticles. Nat Protoc. 2006; 1(6):3153-8.

Nehilla BJ, Vu TQ, Desai TA. Stoichiometry-dependent formation of quantum dot-antibody bioconjugates: a complementary atomic force microscopy and agarose gel electrophoresis study. J Phys Chem B. 2005 Nov 10; 109(44):20724-30.

Tao SL, Desai TA. Micromachined devices: the impact of controlled geometry from cell-targeting to bioavailability. J Control Release. 2005 Dec 05; 109(1-3):127-38.

La Flamme KE, Mor G, Gong D, La Tempa T, Fusaro VA, Grimes CA, Desai TA. Nanoporous alumina capsules for cellular macroencapsulation: transport and biocompatibility. Diabetes Technol Ther. 2005 Oct; 7(5):684-94.

Popat KC, Leary Swan EE, Desai TA. Modeling of RGDC film parameters using X-ray photoelectron spectroscopy. Langmuir. 2005 Aug 02; 21(16):7061-5.

Tao SL, Desai TA. Gastrointestinal patch systems for oral drug delivery. Drug Discov Today. 2005 Jul 01; 10(13):909-15.

Swan EE, Popat KC, Desai TA. Peptide-immobilized nanoporous alumina membranes for enhanced osteoblast adhesion. Biomaterials. 2005 May; 26(14):1969-76.

Vu TQ, Maddipati R, Blute TA, Nehilla BJ, Nusblat L, Desai TA. Peptide-conjugated quantum dots activate neuronal receptors and initiate downstream signaling of neurite growth. Nano Lett. 2005 Apr; 5(4):603-7.

Norman JJ, Desai TA. Control of cellular organization in three dimensions using a microfabricated polydimethylsiloxane-collagen composite tissue scaffold. Tissue Eng. 2005 Mar-Apr; 11(3-4):378-86.

Swan EE, Popat KC, Grimes CA, Desai TA. Fabrication and evaluation of nanoporous alumina membranes for osteoblast culture. J Biomed Mater Res A. 2005 Mar 01; 72(3):288-95.

Tan W, Desai TA. Microscale multilayer cocultures for biomimetic blood vessels. J Biomed Mater Res A. 2005 Feb 01; 72(2):146-60.

Sharma S, Desai TA. Nanostructured antifouling poly(ethylene glycol) films for silicon-based microsystems. J Nanosci Nanotechnol. 2005 Feb; 5(2):235-43.

Sharma S, Tan W, Desai TA. Improving the integrity of three-dimensional vascular patterns by poly(ethylene glycol) conjugation. Bioconjug Chem. 2005 Jan-Feb; 16(1):18-22.

Sarkar S, Dadhania M, Rourke P, Desai TA, Wong JY. Vascular tissue engineering: microtextured scaffold templates to control organization of vascular smooth muscle cells and extracellular matrix. Acta Biomater. 2005 Jan; 1(1):93-100.

Popat KC, Leary Swan EE, Mukhatyar V, Chatvanichkul KI, Mor GK, Grimes CA, Desai TA. Influence of nanoporous alumina membranes on long-term osteoblast response. Biomaterials. 2005 Aug; 26(22):4516-22.

Desai TA, West T, Cohen M, Boiarski T, Rampersaud A. Nanoporous microsystems for islet cell replacement. Adv Drug Deliv Rev. 2004 Sep 22; 56(11):1661-73.

Sharma S, Johnson RW, Desai TA. XPS and AFM analysis of antifouling PEG interfaces for microfabricated silicon biosensors. Biosens Bioelectron. 2004 Sep 15; 20(2):227-39.

Popat KC, Mor G, Grimes CA, Desai TA. Surface modification of nanoporous alumina surfaces with poly(ethylene glycol). Langmuir. 2004 Sep 14; 20(19):8035-41.

Nehilla BJ, Popat KC, Vu TQ, Chowdhury S, Standaert RF, Pepperberg DR, Desai TA. Neurotransmitter analog tethered to a silicon platform for neuro-BioMEMS applications. Biotechnol Bioeng. 2004 Sep 05; 87(5):669-74.

Cai Q, Zeng K, Ruan C, Desai TA, Grimes CA. A wireless, remote query glucose biosensor based on a pH-sensitive polymer. Anal Chem. 2004 Jul 15; 76(14):4038-43.

Popat KC, Desai TA. Poly(ethylene glycol) interfaces: an approach for enhanced performance of microfluidic systems. Biosens Bioelectron. 2004 Apr 15; 19(9):1037-44.

Tan W, Desai TA. Layer-by-layer microfluidics for biomimetic three-dimensional structures. Biomaterials. 2004 Mar-Apr; 25(7-8):1355-64.

Leoni L, Desai TA. Micromachined biocapsules for cell-based sensing and delivery. Adv Drug Deliv Rev. 2004 Feb 10; 56(2):211-29.

Sharma S, Johnson RW, Desai TA. Evaluation of the stability of nonfouling ultrathin poly(ethylene glycol) films for silicon-based microdevices. Langmuir. 2004 Jan 20; 20(2):348-56.

Attiah DG, Kopher RA, Desai TA. Characterization of PC12 cell proliferation and differentiation-stimulated by ECM adhesion proteins and neurotrophic factors. J Mater Sci Mater Med. 2003 Nov; 14(11):1005-9.

Tao SL, Lubeley MW, Desai TA. Synthesis of cytoadhesive poly(methylmethacrylate) for applications in targeted drug delivery. J Biomed Mater Res A. 2003 Nov 01; 67(2):369-75.

Motlagh D, Hartman TJ, Desai TA, Russell B. Microfabricated grooves recapitulate neonatal myocyte connexin43 and N-cadherin expression and localization. J Biomed Mater Res A. 2003 Oct 01; 67(1):148-57.

Saifuddin U, Vu TQ, Rezac M, Qian H, Pepperberg DR, Desai TA. Assembly and characterization of biofunctional neurotransmitter-immobilized surfaces for interaction with postsynaptic membrane receptors. J Biomed Mater Res A. 2003 Jul 01; 66(1):184-91.

Motlagh D, Senyo SE, Desai TA, Russell B. Microtextured substrata alter gene expression, protein localization and the shape of cardiac myocytes. Biomaterials. 2003 Jun; 24(14):2463-76.

Boateng SY, Hartman TJ, Ahluwalia N, Vidula H, Desai TA, Russell B. Inhibition of fibroblast proliferation in cardiac myocyte cultures by surface microtopography. Am J Physiol Cell Physiol. 2003 Jul; 285(1):C171-82.

Tan W, Desai TA. Microfluidic patterning of cells in extracellular matrix biopolymers: effects of channel size, cell type, and matrix composition on pattern integrity. Tissue Eng. 2003 Apr; 9(2):255-67.

Tao SL, Lubeley MW, Desai TA. Bioadhesive poly(methyl methacrylate) microdevices for controlled drug delivery. J Control Release. 2003 Mar 07; 88(2):215-28.

Tao SL, Desai TA. Microfabricated drug delivery systems: from particles to pores. Adv Drug Deliv Rev. 2003 Feb 24; 55(3):315-28.

Davis DH, Giannoulis CS, Johnson RW, Desai TA. Immobilization of RGD to < 1 1 1 > silicon surfaces for enhanced cell adhesion and proliferation. Biomaterials. 2002 Oct; 23(19):4019-27.

Desai TA. Microfabrication technology for pancreatic cell encapsulation. Expert Opin Biol Ther. 2002 Aug; 2(6):633-46.

Ahmed A, Bonner C, Desai TA. Bioadhesive microdevices with multiple reservoirs: a new platform for oral drug delivery. J Control Release. 2002 Jun 17; 81(3):291-306.

Weis RP, Montchamp JL, Coffer JL, Attiah DG, Desai TA. Calcified nanostructured silicon wafer surfaces for biosensing: effects of surface modification on bioactivity. Dis Markers. 2002; 18(4):159-65.

Giannoulis CS, Desai TA. Characterization of proteins and fibroblasts on thin inorganic films. J Mater Sci Mater Med. 2002 Jan; 13(1):75-80.

Tan W, Krishnaraj R, Desai TA. Evaluation of nanostructured composite collagen--chitosan matrices for tissue engineering. Tissue Eng. 2001 Apr; 7(2):203-10.

Snyder JD, Desai TA. Microscale three-dimensional polymeric platforms for in vitro cell culture systems. J Biomater Sci Polym Ed. 2001; 12(8):921-32.

Desai TA. Micro- and nanoscale structures for tissue engineering constructs. Med Eng Phys. 2000 Nov; 22(9):595-606.

Desai TA, Hansford DJ, Ferrari M. Micromachined interfaces: new approaches in cell immunoisolation and biomolecular separation. Biomol Eng. 2000 Oct; 17(1):23-36.

Deutsch J, Motlagh D, Russell B, Desai TA. Fabrication of microtextured membranes for cardiac myocyte attachment and orientation. J Biomed Mater Res. 2000; 53(3):267-75.

Desai TA, Hansford DJ, Leoni L, Essenpreis M, Ferrari M. Nanoporous anti-fouling silicon membranes for biosensor applications. Biosens Bioelectron. 2000; 15(9-10):453-62.

Desai TA, Chu WH, Rasi G, Sinibaldi-Vallebona P, Guarino E, Ferrari M. Microfabricated biocapsules provide short-term immunoisolation of insulinoma xenografts. Biomed Microdevices. 1999; 1(2):131-8.

Zhang M, Desai T, Ferrari M. Proteins and cells on PEG immobilized silicon surfaces. Biomaterials. 1998 May; 19(10):953-60.

Desai TA, Chu WH, Tu JK, Beattie GM, Hayek A, Ferrari M. Microfabricated immunoisolating biocapsules. Biotechnol Bioeng. 1998 Jan 05; 57(1):118-20.

Mosqueda-Garcia R, Furlan R, Fernandez-Violante R, Desai T, Snell M, Jarai Z, Ananthram V, Robertson RM, Robertson D. Sympathetic and baroreceptor reflex function in neurally mediated syncope evoked by tilt. J Clin Invest. 1997 Jun 01; 99(11):2736-44.