Department of Pharmaceutical Chemistry

Jim Wells, PhD

Professor

My research focuses on developing enabling technologies for protein engineering and drug discovery to understand biology and pave roads to therapeutics.

Brian Shoichet, PhD

Department Chair and Professor

As a faculty member in the Department of Pharmaceutical Chemistry, I develop new methods for drug discovery, adopting two strategies to do so. On the one hand, we reduce biology to its molecular components, and seek to change how these fit together using synthetic molecules we design. On the other...

Adam Renslo, PhD

Professor

I am the School’s representative in collaborations between our academic scientists and industry, aiming to translate the most promising discoveries and technologies from our research into therapies that reach patients.

My research group is engaged at the interface of chemistry and biology. As...

Michelle Arkin, PhD

Professor

My research focuses on the development of drug-like molecules that alter important biological processes. These molecules will help us understand human biology and may lead to the design of new drugs. 

Xiaokun Shu, PhD

Professor

We apply laws of Physics and Chemistry to design tools for Biology, and use the novel tools to understand fascinating Biology and discover life-saving therapeutics.

Daniel Santi, MD, PhD

Professor

Since my retirement in 2000, I became CEO of Kosan Biosciences. I returned to UCSF in 2007 where I served as interim Director of the UCSF CTSI and then Director of Translational Research at QB3.

Bo Huang, PhD

Professor

I am interested in understanding how macromolecular interactions sets up subcellular compartments that control signaling and nuclear domains that regulate gene function. For this goal, I am developing new fluorescence microscopy techniques and engineering new protein and cellular tools, so that the...

Zev Gartner, PhD

Professor

My laboratory is working to understand how cells self-organize into tissues, how the structure of tissues help regulate cell behaviors, and how tissue structure breaks down in diseases like cancer. By understanding these processes we hope to reveal general principles contributing to cancer...

Pamela England, PhD

Professor

Research in the England Lab is broadly focused on developing and applying chemical probes to investigate the structure and function of signaling proteins implicated in fundamental biological processes and human diseases. Execution of these research projects typically involves a combination of...

William DeGrado, PhD

Professor

My research focuses on small molecule and protein design as an approach to understanding macromolecule structure and function.

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