UCSF

Publication highlight: Williams

PSPG student Jasper Williams publishes in Cell

SynNotch T cells drive customized therapeutic responses for cancer and other diseases. SynNotch T cells can be engineered to sense tumor antigens and locally deliver biologics such as antibodies, and can thus be used as a smart platform for local delivery of diverse therapeutic payloads capable of remodeling microenvironments.

Roybal, K.T., Williams, J.Z., Morsut, L., Rupp, L.J., Kolinko, I., Choe, J.H., Walker, W.J., McNally, K.A., Lim, W.A. (2016). Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors. Cell. 167, 419-432.

Tags

Category:
Sites:
PSPG

About the School: The UCSF School of Pharmacy aims to solve the most pressing health care problems and strives to ensure that each patient receives the safest, most effective treatments. Our discoveries seed the development of novel therapies, and our researchers consistently lead the nation in NIH funding. The School’s doctor of pharmacy (PharmD) degree program, with its unique emphasis on scientific thinking, prepares students to be critical thinkers and leaders in their field.