UCSF

Tagged: Research

Stopping cancer in its tracks

Cancer, fundamentally, is a problem of too much growth. For decades, health care providers have tried and failed to slow tumor growth using drugs that interfere with a particular signaling pathway, called PI3K, which is known to operate in proliferating cancer cells.

Canada’s longest living dialysis patient makes push for UCSF’s artificial kidney

Ken Sharp ‘a force to be reckoned with’ in push to fund bioartificial kidney
Thu Jul 19, 2018

Creating the tools to count all of our cells

If it’s hard to take an accurate census of the 325 million people living in the US, it’s even more daunting to survey the 37.2 trillion or so cells that make up the human body. The brain alone, for instance, contains nearly 90 billion neurons, which can be classified into over a thousand distinct cell types.

Update from the Dean – July 2018

Health at the molecular level: Decoding cellular signals, A trigger for tissue repair, Seeding tomorrow’s science; The future of custom care: Tracking cancer drug resistance, Treating malaria and tuberculosis, Quantitative Biosciences Institute’s culture of inclusivity, The genetics of asthma; Ensuring the best possible care: Using the right drugs, Keeping up with the testing boom; Update on the new PharmD curriculum: Welcoming our new students at the end of July; Education accolades: Competition wins, The Grad Slam, Emerging Teaching Scholar Award; Honors and awards: Faculty members recognized for their contributions; Celebrating our alumni: Remembering Alumni Weekend, Alumni award winners; In memoriam: Chin-Tzu Peng: A legacy of discovery and leadership

Drilling down to the details of opioid signaling

Despite using opioids for centuries for pain management, we still don’t have a complete understanding of how drugs like morphine and oxycodone actually work. And that’s a problem for patients, who must weather side effects that can range from nausea and constipation to cognitive impairment, addiction, and, at high doses, even death.

It’s in the DNA: Pharmacogenetics Class

In BPS 115, (Genetics and Pharmacogenetics), first year PharmD students study themselves at a genetic level using pharmacogenetic testing, and volunteer to share their data with each other. Data is aggregated for selected drug metabolizing genes-of-interest. These results are presented on “Reveal Day,” where students role-play doctor-patient consultations and review each “patient’s” proclivity for developing certain conditions and diseases. (See video links, below)

Manglik named a 2018 Pew Biomedical Scholar

Aashish Manglik, MD, PhD, the newest member of the faculty of the UCSF School of Pharmacy’s Department of Pharmaceutical Chemistry, was named a Pew Biomedical Scholar on June 14.

Seiple named a 2018 Beckman Young Investigator

The Beckman Young Investigator award provides research support to the most promising young faculty members in the early stages of their academic careers in the chemical and life sciences.

Tumor analysis, prediction of transplant complications, and management of blood potassium levels take top honors at annual seminar

The Gary Rifkind Awards recognize and celebrate clinical pharmacy research.

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