UCSF

Tagged: Research

Creating an inexhaustible database for drug molecules

Mon Feb 11, 2019
Shoichet in his office
Credit: 
Elisabeth Fall

Brian Shoichet, PhD, brought his drug discovery software to an enormous database of small molecules.

School of Pharmacy researchers helped a free public database of potential drug molecules grow 100-fold.

Tamraz is featured PGRN Investigator

Tue Feb 5, 2019
Tamraz
Credit: 
Elisabeth Fall

Bani Tamraz, PharmD, PhD, is the featured Pharmacogenomics Research Network Investigator (PGRN) for February 2019. An article on the group’s website describes his overall goal to build a patient-oriented program of pharmacogenetics (PGx) research, teaching, and clinical practice that utilizes genetics for therapy optimization at UCSF and beyond. Read the full article here: Featured PGRN Investigators

QBI fellowship fosters curiosity and perseverance for women scientists

Mon Jan 28, 2019
Jacqueline Kyosiimire-Lugemwa, PhD
Credit: 
QBI

Jacqueline Kyosiimire-Lugemwa, PhD, was the first recipient of QBI's Scholarship for Women from Developing Nations in Biosciences. 

Jacqueline Kyosiimire-Lugemwa, the first recipient of QBI’s Scholarship for Women from Developing Nations in Biosciences, spent a year at UCSF in which her perseverance in the sciences was tested. She recently returned to her home country of Uganda more ready than ever to tackle big questions about HIV.

CRISPR-based obesity treatment shows promise for other diseases

Thu Jan 17, 2019
Ahituv, right, works in his lab with postdoc Fumitaka Inoue
Credit: 
Susan Merrell

Nadav Ahituv, PhD, right, was able to curb obesity in mice by tweaking two genes involved in controlling appetite.

A recent study by Nadav Ahituv, PhD, showed that obesity caused by a gene mutation could be treated in animal models.

Keiser receives $2.5 million to apply machine learning towards new therapies for Alzheimer’s, Parkinson’s

Tue Jan 8, 2019
Michael Keiser, PhD
Credit: 
UCSF

Michael Keiser, PhD, received a Ben Barres Early Career Acceleration Award from the Chan Zuckerberg Initiative, which will support his research into novel therapies for neuro­de­gener­a­tion.

Michael Keiser, PhD, received a Ben Barres Early Career Acceleration Award from the Chan Zuckerberg Initiative, which will fund his research into novel therapies for neurodegeneration.

Combination drug therapy overcomes drug-resistant lung cancer in the lab

Wed Dec 19, 2018
Chest x-ray, showing a possible lung cancer tumor.
Credit: 
National Cancer Institute

A chest x-ray showing a possible lung cancer tumor (National Cancer Institute)

Many types of lung cancer thwart even the most targeted of therapies due to drug resistance, but a group of UCSF scientists led by Sourav Bandyopadhyay, PhD, have now shown that adding a second drug into treatment regimens can overcome this resistance in lab-grown, lung cancer cell lines.

QBI scientists decipher how Ebola, dengue, and Zika infect human cells

Fri Dec 14, 2018
Nevan Krogan, PhD
Credit: 
Chris Goodfellow (Gladstone Institutes)

Nevan Krogan, PhD, senior author on the two studies and director of QBI

In a pair of recent studies, scientists at the Quantitative Biosciences Institute uncovered how Ebola, dengue, and Zika hijack human proteins to infect human cells, findings that point to new approaches for treating these diseases.

Research points to individualized treatments for curing TB

Tue Nov 20, 2018
Savic speaking at podium

Rada Savic, PhD, senior author on the study, presented her team's work on tuberculosis treatments at the 49th Union World Conference on Lung Health in The Hague, The Netherlands, in late October 2018.

Tuberculosis is usually treated with a six month regimen of daily antibiotics, but millions of patients do not recover from the disease during treatment. Rada Savic’s team showed that adjusting the duration of this regimen based on disease severity could lead to better outcomes.

School of Pharmacy emeriti Kollman, Kuntz, and Langridge honored with UCSF Medal

Thu Nov 15, 2018
composite of Langridge, Kollman, Kuntz, and a wasabi receptor computer graphic
Drug discovery today begins with computation rather than test tube experimentation. Three School of Pharmacy faculty emeriti, Robert Langridge, Irwin “Tack” Kuntz, and the late Peter Kollman, were awarded the UCSF Medal for creating computational tools for drug discovery that are now used worldwide.

Update from the Dean – November 2018

Fri Nov 9, 2018
Guglielmo, PharmD
Credit: 
Elisabeth Fall

“The best path forward for patients and for our health system lies with empowering pharmacists to practice at the top of their profession.”

Curriculum transformation, An expanded role, Gaining recognition, Graduate match rate; School of Pharmacy scientists receive UCSF Medal: Founding fathers of drug discovery honored; Beyond drugs, Two artificial pancreas projects, Bringing prosthetics to patients; Beyond drugs, Two artificial pancreas projects, Bringing prosthetics to patients; Advancing the fight against cancer, Combining drug therapies, Mapping cells; In memoriam: Robert D. Gibson A lifetime of pharmacy and advocacy

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