UCSF

Researchers develop safer opioid painkiller from scratch

Brian Shoichet, PhD, professor of pharmaceutical chemistry in the UCSF School of Pharmacy, is co-senior author of a study published in Nature that used the newly deciphered atomic structure of the brain’s “morphine receptor” to custom engineer a novel drug candidate that blocked pain as effectively as morphine in mouse experiments but did not share the potentially deadly side effects typical of opioid drugs.

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Researchers develop safer opioid painkiller from scratch

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About the School: The UCSF School of Pharmacy aims to solve the most pressing health care problems and strives to ensure that each patient receives the safest, most effective treatments. Our discoveries seed the development of novel therapies, and our researchers consistently lead the nation in NIH funding. The School’s doctor of pharmacy (PharmD) degree program, with its unique emphasis on scientific thinking, prepares students to be critical thinkers and leaders in their field.