antibiotics

Resistant bacteria meet their match with custom antibiotics

Mon Oct 26, 2020

Paul Gunning (Cell Image Library)

A scanning electron micrograph image of methicillin resistant staphylococcus aureus (MRSA) bacteria.

“Molecular building blocks” give antibiotics an edge over drug-resistant bacteria.

Using antibiotics to stop contamination in cell cultures changes them, study finds

Thu Aug 31, 2017

Ann Hane Ryu, a graduate student in the lab of Nadav Ahituv, PhD, works with cell cultures.

The common lab practice of adding antibiotics to cell cultures to prevent contamination can actually induce genetic changes in the cells, a paper senior-authored by Nadav Ahituv, PhD, found. Ahituv is a faculty member in the Department of Bioengineering and Therapeutic Sciences, a joint department...

Koda-Kimble Seed Award recipients explore ‘blue-sky’ projects

Mon Feb 27, 2017

Mary Anne Koda-Kimble, PharmD

Recipients of the UCSF School of Pharmacy 2017 Mary Anne Koda-Kimble Seed Award for Innovation will explore ideas ranging from possible new ways to treat obesity to new ways of accessing antibiotic-producing microbes found in soil.

Fujimori delivers 2017 Byers Award Lecture on tackling antibiotic resistance

Wed Feb 15, 2017

Susan Merrell

Danica Galonić Fujimori, PhD, delivers the 2017 Byers Award Lecture in Basic Science. Her topic was the problem of antibiotic resistance and how research may help keep drugs effective.

Since Alexander Fleming discovered penicillin in 1940, countless lives have been saved by antibiotics. But their effectiveness is severely compromised by the emergence of antibiotic resistant strains of bacteria, accelerated by the over-prescription of antibiotics and their widespread use as growth...

MacDougall study finds severe sepsis alert speeds drug delivery

Tue Dec 22, 2015

Elisabeth Fall

Conan MacDougall, PharmD, MAS

Sepsis occurs when the body responds to an infection with a mix of tissue-damaging inflammation and anti-inflammatory responses. This biological storm can lead to acute organ dysfunction (severe sepsis) and dropping blood pressure that does not respond to intravenous fluids (septic shock).

Yang study demonstrates simulator to study antibiotic dosing against biofilms

Thu Oct 29, 2015

Katherine Yang

In these multiple images of P. aeruginosa biofilm a bacterial community that takes the form of mushroom-like structures. The main, upper left image looks down at the biofilm, the lower, right-hand images show cross-sections. This biofilm was cultured from the airways of a patient with cystic fibrosis.

Nearly every human bacterial infection—including some of the most serious, life threatening, and costly to treat—can take the form of a biofilm, in which bacteria aggregate into structured communities that enclose themselves within a secreted slime.

Ian Seiple, PhD

Wed Sep 2, 2015

Associate Professor

Our research focuses on the application of modern chemical synthesis to biological challenges. Primary branches include complex molecule synthesis, reaction development, and de novo molecular design. Each project is chosen based on its fundamental scientific merit and its potential for immediate...

Label warnings, antibiotic measurements, cancer therapies, and smoking interventions take top honors at annual seminar

Thu May 22, 2014

Rifkind Award Winners (clockwise from upper left) Tien Ho, PharmD; Bao Dao, PharmD, MBA; Robin Corelli, PharmD; Alicia Harvey, PharmD.

Studies of improved over-the-counter acetaminophen warning labels, more accurate measurements of antibiotics in hospitalized patients, therapies for metastatic breast cancer, and methods for training pharmacy personnel to help smokers quit took top honors at the Department of Clinical Pharmacy’s...

Fischbach receives Packard Fellowship

Mon Oct 17, 2011

Michael Fischbach, PhD

Michael Fischbach, PhD, who studies drug-like molecules produced by human gut bacteria, has been awarded one the 16 prestigious 2011 Packard Fellowships in Science and Engineering.

Fischbach and Desai focus on “micro” solutions to improve health with drugs

Thu Jun 30, 2011

Faculty members in the Department of Bioengineering and Therapeutic Sciences, UCSF Schools of Pharmacy and Medicine, share their research on the human microbiome and microfabricated drug delivery systems and their hopes for how their science will improve the health of patients.

Topics and Expertise: antibiotics