Drug Discovery

School of Pharmacy scientists unearth a new target for treating Parkinson’s disease

Thu Mar 7, 2019

Neuronal protein with newly-identified drug target highlighted

A team led by Pamela England, PhD, identified a new target (yellow) for future Parkinson’s disease therapies within the Nurr1 protein (blue).

Scientists in the UCSF School of Pharmacy recently identified the first drug-binding target site on a molecule known to play a role in Parkinson's disease, opening the door to a new generation of therapies for the condition.

Creating an inexhaustible database for drug molecules

Mon Feb 11, 2019

Elisabeth Fall

Brian Shoichet, PhD, brought his drug discovery software to an enormous database of small molecules.

School of Pharmacy researchers helped a free public database of potential drug molecules grow 100-fold.

Fraser appointed to Bowes Biomedical Investigator Program

Wed Jan 9, 2019

Elisabeth Fall

James Fraser, PhD, developed new ways of doing crystallography over a wide range of temperatures.

Fraser developed several new tools for creating maps of macromolecules, a critical first step for finding new drugs.

Keiser receives $2.5 million to apply machine learning towards new therapies for Alzheimer’s, Parkinson’s

Tue Jan 8, 2019

UCSF

Michael Keiser, PhD, received a Ben Barres Early Career Acceleration Award from the Chan Zuckerberg Initiative, which will support his research into novel therapies for neurodegeneration.

Michael Keiser, PhD, received a Ben Barres Early Career Acceleration Award from the Chan Zuckerberg Initiative, which will fund his research into novel therapies for neurodegeneration.

School of Pharmacy emeriti Kollman, Kuntz, and Langridge honored with UCSF Medal

Thu Nov 15, 2018

composite of Langridge, Kollman, Kuntz, and a wasabi receptor computer graphic

Drug discovery today begins with computation rather than test tube experimentation. Three School of Pharmacy faculty emeriti, Robert Langridge, Irwin “Tack” Kuntz, and the late Peter Kollman, were awarded the UCSF Medal for creating computational tools for drug discovery that are now used worldwide.

Explore molecular targets in daring new ways

Wed Sep 5, 2018

Showcasing School science and change at Alumni Weekend 2018

Fri Jun 15, 2018

Levi Gadye

B. Joseph Guglielmo, PharmD, addressed Half Century Club Luncheon attendees.

Sessions include: quickly identifying molecules that show potential as drugs; improving access and treatments for AIDS, malaria, and tuberculosis; why curiosity and imagination are taking the place of memorization the PharmD curriculum. Honoring the Class of 1968. Kennedy receives Distinguished...

Seiple named a 2018 Beckman Young Investigator

Tue Jun 12, 2018

Ian Seiple, PhD

The Beckman Young Investigator award provides research support to the most promising young faculty members in the early stages of their academic careers in the chemical and life sciences.

Prien and MacWilliam bequests establish new endowed professorships

Wed Dec 7, 2016

Foresight, newsletter of UCSF Office of Gift & Endowment Planning

Ernest Prien, BS ’34 and Mary MacWilliam, EdD, UC Berkeley, 1956

The UCSF School of Pharmacy has established new endowed faculty positions to be held by the chairs of two School departments.

Three generations reflect shifts in nation, pharmacy profession

Wed Oct 19, 2016

Cindy Chew

Sharon (McPartland) Leaf, PharmD ’81, with her daughter, first-year student pharmacist Megan Lau.

When Megan Lau donned her white coat with fellow student pharmacists in the incoming class of 2020 last week, it was more than your standard rite of professional passage.

Topics and Expertise: Drug Discovery