UCSF

Rada Savic, PhD

Co-Vice Dean of Graduate Pharmacy Education Programs
Professor
Savic
Phone: +1 415 502-0640
1700 4th St, Rm 503C
UCSF Box 2552
San Francisco, CA 94158
United States

Affiliations

What I do

I co-lead the School’s plans for developing graduate education programs in the computational and experimental sciences, along with Brian Shoichet, PhD. These programs are geared toward giving the School’s PharmD students greater career opportunities throughout biomedicine. 

As a faculty member in the Department of Bioengineering and Therapeutic Sciences, I investigate optimal drug discovery and development approaches using computational methods. I integrate data and knowledge to determine the optimal choices of precise and personalized treatments.

My research expertise

Pharmacometrics, precision dosing, clinical pharmacology, systems pharmacology, precision medicine, pharmacogenetics, translational sciences, nonlinear mixed effects models, Infectious diseases, tuberculosis, malaria, HIV cure, developmental pharmacology, disease progression models, drug development, NONMEM, modeling and simulations, clinical trial design, pediatrics, pharmacokinetics, pharmacodynamics, data science

Professional background

Biography

My research uses computational methods to study the dynamic interplay between disease progression, treatment regimen, and drug and biomarker response across relevant scales (molecule, cell, tissue, organ & whole body) to determine causal links underlying variability in (safety and efficacy) clinical outcomes. By integrating multi-scale, and multi-level clinical data, we aim to determine the right dose, schedule, and treatment duration of various therapies, potentially bringing novel, precise and personalized treatment options to patients with unmet need more quickly.

Research keywords

  • Nonlinear mixed effects models
  • Pyrazinamide
  • quantitative pharmacology
  • tuberculosis
  • Meningeal
  • Infectious diseases
  • Precision Dosing
  • precision medicine
  • Pulmonary
  • HIV Cure
  • Data Science
  • Pregnancy Complications
  • Parasitic
  • Antitubercular Agents
  • Developmental Pharmacology
  • Quinolines
  • Rifampin
  • Systems Pharmacology
  • malaria
  • pharmacology
  • clinical
  • Drug Dosage Calculations
  • Isoniazid
  • Pharmacometrics
  • Translational Sciences
  • Disease progression models
  • clinical pharmacology
  • Artemisinins
  • pharmacogenetics
  • antibiotics
  • Antitubercular
  • Multidrug-Resistant
  • Multiple sclerosis
  • pharmacokinetics
  • tuberculosis
  • Rifampin
  • Isoniazid
  • Latent Tuberculosis
  • Pyrazinamide
  • Pregnancy Complications, Parasitic
  • Tuberculosis, Pulmonary
  • Tuberculosis, Multidrug-Resistant
  • Antibiotics, Antitubercular
  • Artemisinins
  • pharmacokinetics
  • Antimalarials
  • Mycobacterium tuberculosis
  • Antitubercular Agents
  • Quinolines