Tagged: proteins

Professor

I am interested in building proteins in living cells using new amino acids. By designing novel properties into the new amino acids, my lab probes biological processes in their native settings and engineer unique biomolecules to understand disease mechanisms and to develop new protein drugs.

Assistant Professor

Our group investigates how drugs affect entire networks of proteins in the body at once to achieve their therapeutic effects, via computational predictions paired with experimental testing.

Biophysicist James Fraser, PhD, has been named a 2014 Searle Scholar. His laboratory will be awarded $300,000 in funding over the next three years to support his research into more accurately and precisely describing the ways that protein molecules change shape to carry out the functions of life in...

Professor

I am a biophysicist. My research is focused on discovering the macromolecular structure and dynamics of proteins—defining conformational states essential for function and understanding transitions between these states.

Professor

My research seeks to invent approaches to engineer new biological functions at multiple scales, ranging from atomic details to macromolecular machines to cellular processes. By building new functions through a combination of computational design and experimental engineering, I also hope to learn...

Professor

My research interests focus on the development of state of the art methodologies in mass spectrometry for use in advancing our global knowledge of human biology, specifically the dynamic, epigenetic modulation and regulation of the proteome.

Professor

Our lab develops new methods for drug discovery, adopting two strategies to do so. On the one hand, we reduce biology to its molecular components, and seek to change how these fit together using synthetic molecules we design. On the other hand, we investigate how the biological molecules operate...

Professor Emeritus

Since retiring, I serve as a consultant for current Department faculty.

Professor

Research in my lab focuses on atomic-level mechanisms of protein regulation, protein-ligand interactions, and computer-aided drug design. My approach is to employ physics-based energy models for predictive protein modeling. Projects in my lab combine algorithm development and biological...

Professor

My lab develops software tool for visualizing and analyzing molecular structures at scales ranging from the atomic to the supramolecular.