Research

CRISPR-based obesity treatment shows promise for other diseases

Thu Jan 17, 2019

Ahituv, right, works in his lab with postdoc Fumitaka Inoue

Susan Merrell

Nadav Ahituv, PhD, right, was able to curb obesity in mice by tweaking two genes involved in controlling appetite.

A recent study by Nadav Ahituv, PhD, showed that obesity caused by a gene mutation could be treated in animal models.

Keiser receives $2.5 million to apply machine learning towards new therapies for Alzheimer’s, Parkinson’s

Tue Jan 8, 2019

UCSF

Michael Keiser, PhD, received a Ben Barres Early Career Acceleration Award from the Chan Zuckerberg Initiative, which will support his research into novel therapies for neurodegeneration.

Michael Keiser, PhD, received a Ben Barres Early Career Acceleration Award from the Chan Zuckerberg Initiative, which will fund his research into novel therapies for neurodegeneration.

Combination drug therapy overcomes drug-resistant lung cancer in the lab

Wed Dec 19, 2018

National Cancer Institute

A chest x-ray showing a possible lung cancer tumor (National Cancer Institute)

Many types of lung cancer thwart even the most targeted of therapies due to drug resistance, but a group of UCSF scientists led by Sourav Bandyopadhyay, PhD, have now shown that adding a second drug into treatment regimens can overcome this resistance in lab-grown, lung cancer cell lines.

QBI scientists decipher how Ebola, dengue, and Zika infect human cells

Fri Dec 14, 2018

Chris Goodfellow (Gladstone Institutes)

Nevan Krogan, PhD, senior author on the two studies and director of QBI

In a pair of recent studies, scientists at the Quantitative Biosciences Institute uncovered how Ebola, dengue, and Zika hijack human proteins to infect human cells, findings that point to new approaches for treating these diseases.

Research points to individualized treatments for curing TB

Tue Nov 20, 2018

Rada Savic, PhD, senior author on the study, presented her team's work on tuberculosis treatments at the 49th Union World Conference on Lung Health in The Hague, The Netherlands, in late October 2018.

Tuberculosis is usually treated with a six month regimen of daily antibiotics, but millions of patients do not recover from the disease during treatment. Rada Savic’s team showed that adjusting the duration of this regimen based on disease severity could lead to better outcomes.

School of Pharmacy emeriti Kollman, Kuntz, and Langridge honored with UCSF Medal

Thu Nov 15, 2018

composite of Langridge, Kollman, Kuntz, and a wasabi receptor computer graphic

Drug discovery today begins with computation rather than test tube experimentation. Three School of Pharmacy faculty emeriti, Robert Langridge, Irwin “Tack” Kuntz, and the late Peter Kollman, were awarded the UCSF Medal for creating computational tools for drug discovery that are now used worldwide.

Update from the Dean – November 2018

Fri Nov 9, 2018

Elisabeth Fall

Dean B. Joseph Guglielmo, PharmD

Curriculum transformation, An expanded role, Gaining recognition, Graduate match rate; School of Pharmacy scientists receive UCSF Medal: Founding fathers of drug discovery honored; Beyond drugs, Two artificial pancreas projects, Bringing prosthetics to patients; Beyond drugs, Two artificial...

Bringing artificial limbs to patients who need them

Thu Nov 8, 2018

Matheny demonstrates prosthetic arm to onlookers

Marine Corps Sgt. Drew Tech, U.S. Department of Defense

Johnny Matheny demonstrates how a modular prosthetic limb works during DARPA Demo Day 2016 at the Pentagon, May 11, 2016. Matheny is a test subject with the Johns Hopkins Applied Physics Lab.

The patient perspective on prosthetic limbs currently doesn’t factor into the FDA approval process. Leslie Wilson and Matthew Garibaldi are surveying patient preferences to speed access to the next generation of prosthetics.

Checking in with Sourav Bandyopadhyay

Fri Oct 26, 2018

Sourav Bandyopadhyay, PhD

Prof. Sourav Bandyopadhyay has been assiduous both in the laboratory and at his desk.

PSPG student Imperial’s work accepted in Nature Medicine

Mon Oct 22, 2018

The work of Marjorie Imperial is being used as a tool to guide implementation strategies on adherence worldwide by BMGF and has initiated a technical workshop run by WHO this year. Congratulations, Marjorie!

Categories: Research