Research

Nanobody-based antiviral developed at UCSF effectively blocks SARS-CoV-2 in the lab

Wed Aug 12, 2020

The antiviral invented by Aashish Manglik, PhD, and colleagues is effective at blocking SARS-CoV-2 infection even as an aerosolized spray, according to laboratory testing.

School scientists developed an antiviral that fights SARS-CoV-2 that can be given as a nasal spray.

UCSF’s artificial kidney project wins major award, now one step closer to potentially changing lives

Mon Aug 10, 2020

Dozens of presumed inactive ingredients may impact human biology

Wed Jul 29, 2020

Morguefile.com

School scientists have found that various inactive ingredients in drugs, known as excipients, may produce unwanted side effects in the human body.

School scientists identify excipients with potential to cause side effects

The Kidney Project wins KidneyX Award to enable simpler, safer at-home dialysis

Wed Jul 22, 2020

The Kidney Project's iHemo offers patients a safer, in-home alternative to dialysis

The Kidney Project's iHemo implantable dialysis system received a $500,000 award to speed its development into an approved therapy for patients.

School's efforts to develop artificial kidney receive $500,000 boost

How targeting a key SARS-CoV-2 enzyme could lead to an antiviral drug

Fri Jul 10, 2020

Elisabeth Fall

James Fraser, PhD

The chemical fragments could bind to and disable an enzyme that helps the virus replicate.

SARS-CoV-2 may spur growth of molecular “railways” out of infected cells, School scientists show

Thu Jul 2, 2020

NIAID/NIH

SARS-CoV-2 viral particles and human cells

UCSF-led collaboration uncovers new avenues for COVID-19 drug discovery

COVID-19 relies on cell’s ‘master regulators’ for survival

Tue Jun 30, 2020

QBI Coronavirus Research Group identifies drugs that block SARS-CoV-2 in the laboratory

Thu May 28, 2020

Susan Merrell

Nevan Krogan, PhD (standing), leads a meeting of the QBI Coronavirus Research Group with fellow UCSF faculty members (seated from left) Danica Galonić Fujimori, PhD; Natalia Jura, PhD; James Fraser, PhD; and David Agard, PhD.

The QBI Coronavirus Research Group found six drugs that effectively beat back SARS-COV-2 in the laboratory.

Update from the Dean: Building community while staying safe

Fri May 22, 2020

Elisabeth Fall

Dean B. Joseph Guglielmo, PharmD

Our COVID-19 response: As we return to campus, everyone’s well-being is our top concern. But we also need to consider the need to maintain and strengthen community.

Dumont Lab reveals workings of macromolecular machines

Wed May 20, 2020

Sophie Dumont, PhD

Categories: Research