Topics and Expertise: drug transporters

Giacomini to lead largest study of genetic, ethnic differences in effectiveness of leading diabetes drug

In people with type 2 diabetes, the body is less able to use the hormone insulin to regulate blood sugar. The disease affects 350 million patients globally—including 29 million in the United States, where it is the leading cause of blindness, kidney failure, and non-accident-related amputations.

Study discovers why leading gout medication is ineffective for many

Allopurinol, the first-choice medication for treating gout—an excruciatingly painful condition that is the most common form of inflammatory arthritis, afflicts more than eight million Americans, and is on the rise worldwide—is not fully effective in more than half of patients.

Leslie Benet, PhD

Professor

Benet delivers distinguished lecture

Leslie Z. Benet, PhD, faculty member in the UCSF School of Pharmacy delivered the Seventh Distinguished Clinical Research Lecture to the UCSF faculty on October 17, 2007 on UCSF's Parnassus campus.