Su Guo, PhD

Director, Center for Collaborative Innovation
Phone: +1 415 502-4949
Fax: +1 415 502-8177
1550 4th Street, Bldg 19B, Rm 484D
UCSF Box 2811
San Francisco, CA 94158
United States


What I do

I am interested in how genes regulate brain development and behavior and ultimately impact neuropsychiatric disorders.

As director of the Center for Collaborative Innovation, I lead efforts to increase collaboration between clinical, translational, and discovery science in teaching and research.

Departmental research area

My research expertise

genetics, neuroscience, neuropharmacology, developmental biology

Professional background


Dr. Guo has a broad background in molecular biology, genetics, developmental biology, neurobiology, and is interested in the molecular genetic mechanisms that regulate brain development and function. As a graduate student at Cornell University, she employed the invertebrate model organism C. elegans, and made significant contributions to the discovery of RNA interference (RNAi) as well as understanding of asymmetric cell divisions. After graduation, she became fascinated with how the brain works. As a research and postdoctoral fellow at Harvard Medical School and Genentech Inc. respectively, she carried out neurobiological studies of the development of brain neurotransmitter systems, using the vertebrate genetic model organism zebrafish. After establishing her independent research lab at the University of California, San Francisco, Dr. Guo has continued to study the molecular genetics of neural development and has expanded her research into the understanding of behavior. With her research, Dr. Guo strives to make significant contributions to our basic understanding of the brain and the mind, as well as to help treat neuropsychiatric disorders.

Research keywords

  • noradrenaline
  • regulation of camouflage
  • Stem Cells
  • serotonin
  • drug and alcohol addiction
  • parkinson's disease
  • Zebrafish
  • reward/emotion-related neural circuits and behavior
  • dopamine
  • neurodegeneration
  • Asymmetric Cell Division
  • Prosencephalon
  • Receptors, Notch
  • Ethanol
  • Zebrafish
  • Behavior, Animal
  • Dopaminergic Neurons
  • Paraventricular Hypothalamic Nucleus
  • Avoidance Learning
  • Choice Behavior
  • Larva
  • Zebrafish Proteins
  • Corticotropin-Releasing Hormone
  • Neural Stem Cells
  • Central Nervous System Depressants