Rosa Rodriguez-Monguio, PhD, MS

MOC Director and Professor
Department of Clinical Pharmacy
Rodriguez-Monguio
[email protected]
Phone: +1 415 502-6029
521 Parnassus Avenue, Rm 3517
San Francisco, CA 94117
United States

Links

UCSF Profiles

Affiliations

UCSF centers, institutes, and research programs

Director, Medication Outcomes Center

Department committees and service

DEI-AR Committee, 2022-present, Department of Clinical Pharmacy

What I do

My research interests include post-marketing drug safety addressing the health and economic impacts of adverse drug events, drug shortages and interchangeability of therapeutic alternatives, and appropriateness of prescription and utilization patterns of pharmaceuticals, particularly, opioid analgesics, antipsychotics, and systemic antibiotics. The overarching goal of my research is to enhance prescription drug safety and improve patient outcomes while containing the cost of care.

Departmental research area

clinical research
health services and policy research

My research expertise

health economics and outcomes, pharmaceutical economics and policy, drug safety

Clinical expertise

pharmacoeconomics, health policy

Professional background

Degrees

MS, Clinical Research, Massachusetts College of Pharmacy and Health Sciences, 2016
PhD, Health Economics, University of Barcelona, 2001

Research keywords

  • patient safety
  • vulnerable populations
  • Adverse Drug Events
  • Access to Healthcare Services and Pharmaceuticals
  • Health economics and outcomes evaluation
  • Healthcare disparities
  • Drug shortages
  • Pharmaceutical economics and policy
  • Gambling
  • Sulfonylurea Compounds
  • Pain, Postoperative
  • Orphan Drug Production
  • Medication Reconciliation
  • Pharmaceutical Preparations
  • Recidivism
  • United States Food and Drug Administration
  • Analgesics, Opioid
  • Drugs, Generic
  • Drug Prescriptions
  • Drug Industry
  • Drug Approval
  • Ileus
  • Emergence Delirium
1. Technical Advisor, World Health Organization (WHO), Division of Antimicrobial Resistance. Quadripartite Technical Group, 2023
2. Excellence in Precepting Award, UCSF, School of Pharmacy, 2021
3. Dean's Apple Award in recognition to outstanding efforts and commitment to pharmacy education, UCSF, School of Pharmacy, 2020
4. Editorial Board, BMC Health Services Research, 2019
5. Editorial Board, Orphanet Journal of Rare Diseases, 2019
6. Dean’s Apple Award in recognition to outstanding efforts and commitment to pharmacy education, UCSF, School of Pharmacy, 2019
7. Editorial Board, BMC Public Health, 2017
8. Editorial Board, Journal of Mental Health and Addiction, 2016-2017

Publications

Rodriguez-Monguio R, Seoane-Vazquez E, Powers J . A Comparative Assessment of Approvals and Discontinuations of Systemic Antibiotics and Other Therapeutic Areas. Healthcare. 2023; 12(11):1759.
Ghanem B, Seoane-Vazquez E, Brown L, Rodriguez-Monguio R. Analysis of the Gene Therapies Authorized by the United States Food and Drug Administration and the European Medicines Agency. Med Care. 2023 07 01; 61(7):438-447.
Rodriguez-Monguio R, Lun Z, Dickinson DT, Do C, Hyland B, Kocharyan E, Liu L, Steinman MA. Safety implications of concomitant administration of antidepressants and opioid analgesics in surgical patients. Expert Opin Drug Saf. 2023 Jan-Jun; 22(6):477-484.
Althobaiti H, Seoane-Vazquez E, Brown LM, Fleming ML, Rodriguez-Monguio R. Disentangling the Cost of Orphan Drugs Marketed in the United States. Healthcare (Basel). 2023 Feb 13; 11(4).
Rodriguez-Monguio R, Berkley E, Mendoza E, Miller K, Selim S, Trac C, Lun Z, Reisner L. Inpatient administration of opioids and risk for post-operative ileus in older adults. J Opioid Manag. 2022 Jul-Aug; 18(4):317-325.
Langnas E, Bishara A, Croci R, Rodriguez-Monguio R, Wick EC, Chen CL, Guan Z. Opioid prescribing practices at hospital discharge for surgical patients before and after the Centers for Disease Control and Prevention's 2016 opioid prescribing guideline. BMC Anesthesiol. 2022 05 11; 22(1):141.
King B, Spadaro A, Schiff G, Rodriguez-Monguio R, Jordan AO, Flaherty L, Lee WC, Zito J, Fein O, American Public Health Association, Medical Care Section. The American Public Health Association Endorses Single-Payer Health System Reform. Med Care. 2022 06 01; 60(6):397-401.
Rodriguez-Monguio R, Lun Z, Bongiovanni T, Chen CL, Seoane-Vazquez E. Postoperative Respiratory Events in Surgical Patients Exposed to Opioid Analgesic Shortages Compared to Fully Matched Patients Non-exposed to Shortages. Drug Saf. 2022 04; 45(4):359-367.
Langnas E, Rodriguez-Monguio R, Luo Y, Croci R, Dudley RA, Chen CL. The association of multimodal analgesia and high-risk opioid discharge prescriptions in opioid-naive surgical patients. Perioper Med (Lond). 2021 Dec 15; 10(1):60.
Rodriguez-Monguio R, Lun Z, Kehr K, Agustin JP, San Agustin-Nordmeier K, Huynh C, Reisner L. Hospital admission medication reconciliation in high-risk prescription opioid users. Res Social Adm Pharm. 2022 08; 18(8):3379-3385.
Langnas EM, Matthay ZA, Lin A, Harbell MW, Croci R, Rodriguez-Monguio R, Chen CL. Enhanced recovery after surgery protocol and postoperative opioid prescribing for cesarean delivery: an interrupted time series analysis. Perioper Med (Lond). 2021 Nov 15; 10(1):38.
Rodriguez-Monguio R, Montgomery B, Drawbridge D, Packer I, Vincent GM. Substance use treatment services utilization and outcomes among probationers in drug courts compared to a matched cohort of probationers in traditional courts. Am J Addict. 2021 09; 30(5):505-513.
Rodriguez-Monguio R, Naveed M, Seoane-Vazquez E. Predictors of shortages of opioid analgesics in the US: Are the characteristics of the drug company the missing puzzle piece? PLoS One. 2021; 16(3):e0249274.
Trinh TD, Strnad L, Damon L, Dzundza JH, Graff LR, Griffith LM, Hilts-Horeczko A, Olin R, Shenoy S, DeVoe C, Wang L, Rodriguez-Monguio R, Gu TM, Hampton SR, Macapinlac BAC, Yang K, Doernberg SB. Reductions in vancomycin and meropenem following the implementation of a febrile neutropenia management algorithm in hospitalized adults: An interrupted time series analysis. Infect Control Hosp Epidemiol. 2021 09; 42(9):1090-1097.
Chu CE, Law L, Zuniga K, Lin TK, Tsourounis C, Rodriguez-Monguio R, Lazar A, Washington SL, Cooperberg MR, Greene KL, Carroll PR, Pruthi RS, Meng MV, Chen LL, Porten SP. Liposomal Bupivacaine Decreases Postoperative Length of Stay and Opioid Use in Patients Undergoing Radical Cystectomy. Urology. 2021 Mar; 149:168-173.
Rodriguez-Monguio R, Naveed M, Croci R, Gross K, Langnas E, Chen CL, Seoane-Vazquez E. Perioperative Prescribing Practices of Extended-Release Opioids in Noncancer Surgical Patients, 2015-2018. Anesth Analg. 2020 10; 131(4):1249-1259.
Chen CL, Jeffery MM, Krebs EE, Thiels CA, Schumacher MA, Schwartz AJ, Thombley R, Finlayson E, Rodriguez-Monguio R, Ward D, Dudley RA. Long-Term Trends in Postoperative Opioid Prescribing, 1994 to 2014. J Am Acad Orthop Surg Glob Res Rev. 2020 01; 4(1).
Rozenblum R, Rodriguez-Monguio R, Volk LA, Forsythe KJ, Myers S, McGurrin M, Williams DH, Bates DW, Schiff G, Seoane-Vazquez E. Using a Machine Learning System to Identify and Prevent Medication Prescribing Errors: A Clinical and Cost Analysis Evaluation. Jt Comm J Qual Patient Saf. 2020 01; 46(1):3-10.
Shukla V, Seoane-Vazquez E, Fawaz S, Brown L, Rodriguez-Monguio R. The Landscape of Cellular and Gene Therapy Products: Authorization, Discontinuations, and Cost. Hum Gene Ther Clin Dev. 2019 09; 30(3):102-113.
Brand E, Rodriguez-Monguio R, Volber R. Erratum: Gender Differences in Mental Health and Substance Use Disorders and Related Healthcare Services Utilization. Am J Addict. 2019 Jul; 28(4):324.
Shukla V, Seoane E, Souhiela F, Lawrence B, Rodriguez-Monguio R. The Landscape of Cellular and Gene Therapy Products: Cost, Approvals, and Discontinuations. Hum Gene Ther Clin Dev. 2019 Sep;30(3):102-113. doi: 10.1089/humc.2018.201. Epub 2019 Jul 16. 2019.
Seoane-Vazquez E, Shukla V, Rodriguez-Monguio R. Innovation and competition in advanced therapy medicinal products. EMBO Mol Med. 2019 03; 11(3).
Brand E, Rodriguez-Monguio R, Volber R. Gender differences in mental health and substance use disorders and related healthcare services utilization. Am J Addict. 2019 01; 28(1):9-15.
Kron K, Myers S, Volk L, Nathan A, Neri P, Salazar A, Amato MG, Wright A, Karmiy S, McCord S, Seoane-Vazquez E, Eguale T, Rodriguez-Monguio R, Bates DW, Schiff G. Incorporating medication indications into the prescribing process. Am J Health Syst Pharm. 2018 06 01; 75(11):774-783.
Whitehill JM, Rodriguez-Monguio R, Doucette M, Flom E. Driving and riding under the influence of recent marijuana use: Risk factors among a racially diverse sample of young adults. J Ethn Subst Abuse. 2019 Oct-Dec; 18(4):594-612.
Kwon CS, Seoane-Vazquez E, Rodriguez-Monguio R. Cost-effectiveness analysis of metformin+dipeptidyl peptidase-4 inhibitors compared to metformin+sulfonylureas for treatment of type 2 diabetes. BMC Health Serv Res. 2018 02 01; 18(1):78.
Rodriguez-Monguio R, Brand E, Volberg R. The Economic Burden of Pathological Gambling and Co-occurring Mental Health and Substance Use Disorders. J Addict Med. 2018 Jan/Feb; 12(1):53-60.
Balkhi B, Seoane-Vazquez E, Rodriguez-Monguio R. Changes in the utilization of osteoporosis drugs after the 2010 FDA bisphosphonate drug safety communication. Saudi Pharm J. 2018 Feb; 26(2):238-243.
Bowdoin JJ, Rodriguez-Monguio R, Puleo E, Keller D, Roche J. The patient-centered medical home model: healthcare services utilization and cost for non-elderly adults with mental illness. J Ment Health. 2018 Dec; 27(6):574-582.
Rodriguez-Monguio R, Errea M, Volberg R. Comorbid pathological gambling, mental health, and substance use disorders: Health-care services provision by clinician specialty. J Behav Addict. 2017 Sep 01; 6(3):406-415.
Seoane-Vazquez E, Rodriguez-Monguio R, Alqahtani S, Schiff G. Exploring the potential for using drug indications to prevent look-alike and sound-alike drug errors. Expert Opin Drug Saf. 2017 Oct; 16(10):1103-1109.
Qureshi ZP, Haider MR, Rodriguez-Monguio R, Wooten NR, Nikitin RV, Ball S, Barth K, Elk R, Horner R, Bennett C. Opioid Prescription Drug Use and Expenditures in US Outpatient Physician Offices: Evidence from Two Nationally Representative Surveys. Cancer Ther Oncol Int J. 2017; 3(3).
Sawad AB, Seoane-Vazquez E, Rodriguez-Monguio R, Turkistani F. Cost-effectiveness of different strategies for treatment relapsing-remitting multiple sclerosis. J Comp Eff Res. 2017 Mar; 6(2):97-108.
Balkhi B, Seoane-Vazquez E, Rodriguez-Monguio R. OSTEOPOROSIS DRUGS MARKETED IN THE UNITED STATES: GENERIC COMPETITION, PRICING STRUCTURE, AND DISPERSION AMONG PAYERS. Int J Technol Assess Health Care. 2016 Jan; 32(6):385-392.
Rodriguez-Monguio R, Spargo T, Seoane-Vazquez E. Ethical imperatives of timely access to orphan drugs: is possible to reconcile economic incentives and patients' health needs? Orphanet J Rare Dis. 2017 01 05; 12(1):1.
Bin Sawad A, Seoane-Vazquez E, Rodriguez-Monguio R, Turkistani F. Evaluation of the Expanded Disability Status Scale and the Multiple Sclerosis Functional Composite as clinical endpoints in multiple sclerosis clinical trials: quantitative meta-analyses. Curr Med Res Opin. 2016 12; 32(12):1969-1974.
Bowdoin JJ, Rodriguez-Monguio R, Puleo E, Keller D, Roche J. Associations between the patient-centered medical home and preventive care and healthcare quality for non-elderly adults with mental illness: A surveillance study analysis. BMC Health Serv Res. 2016 08 24; 16(1):434.
Bin Sawad A, Seoane-Vazquez E, Rodriguez-Monguio R, Turkistani F. Price analysis of multiple sclerosis disease-modifying therapies marketed in the United States. Curr Med Res Opin. 2016 11; 32(11):1783-1788.
Seoane-Vazquez E, Rodriguez-Monguio R, Alqahtani S. Response to letter to the editor regarding Alqahtani et al. Article on priority review drugs approved by the FDA and the EMA: time for international regulatory harmonization of pharmaceuticals? Pharmacoepidemiol Drug Saf. 2016 06; 25(6):745-6.
Zhang N, Rodriguez-Monguio R, Barenberg A, Gurwitz J. Are Obese Residents More Likely to Be Admitted to Nursing Homes That Have More Deficiencies in Care? J Am Geriatr Soc. 2016 05; 64(5):1085-90.
Zhang N, Lu SF, Xu B, Wu B, Rodriguez-Monguio R, Gurwitz J. Health Information Technologies: Which Nursing Homes Adopted Them? J Am Med Dir Assoc. 2016 05 01; 17(5):441-7.
Seoane-Vazquez E, Rodriguez-Monguio R, Hansen R. Interchangeability, Safety and Efficacy of Modified-Release Drug Formulations in the USA: The Case of Opioid and Other Nervous System Drugs. Clin Drug Investig. 2016 Apr; 36(4):281-92.
Okunna NC, Rodriguez-Monguio R, Smelson DA, Poudel KC, Volberg R. Gambling involvement indicative of underlying behavioral and mental health disorders. Am J Addict. 2016 Mar; 25(2):160-72.
Kwon CS, Seoane-Vazquez E, Rodriguez-Monguio R. FDA safety actions for antidiabetic drugs marketed in the US, 1980-2015. Int J Risk Saf Med. 2016; 28(4):197-211.
Hao J, Rodriguez-Monguio R, Seoane-Vazquez E. Fixed-Dose Combination Drug Approvals, Patents and Market Exclusivities Compared to Single Active Ingredient Pharmaceuticals. PLoS One. 2015; 10(10):e0140708.
Hao J, Rodriguez-Monguio R, Seoane-Vazquez E. Fixed-dose combination and single active ingredient drugs: a comparative cost analysis. Expert Rev Pharmacoecon Outcomes Res. 2016; 16(1):127-34.
Bulzacchelli MT, Sulsky SI, Rodriguez-Monguio R, Karlsson LH, Hill LT. Response to Letter to the Editor: Regarding the Bulzacchelli et al. Article on Injury During U.S. Army Basic Combat Training. Am J Prev Med. 2015 Jul; 49(1):e3-5.
Rodriguez-Monguio R. Capsule commentary on Goetz et al., The effect of charge display on cost of care and physician practice behaviors: a systematic review. J Gen Intern Med. 2015 Jun; 30(6):834.
Alqahtani S, Seoane-Vazquez E, Rodriguez-Monguio R, Eguale T. Priority review drugs approved by the FDA and the EMA: time for international regulatory harmonization of pharmaceuticals? Pharmacoepidemiol Drug Saf. 2015 Jul; 24(7):709-15.
Sulsky SI, Karlsson LH, Bulzacchelli MT, Luippold RS, Rodriguez-Monguio R, Bulathsinhala L, Hill OT. Methodological challenges of using U.S. Army administrative data to identify a cohort of basic combat trainees and descriptive analysis of trends in characteristics that are potential risk factors for training-related injury. Mil Med. 2014 Dec; 179(12):1487-96.
Bulzacchelli MT, Sulsky SI, Rodriguez-Monguio R, Karlsson LH, Hill MO. Injury during U.S. Army basic combat training: a systematic review of risk factor studies. Am J Prev Med. 2014 Dec; 47(6):813-22.
Pellegrini LC, Rodriguez-Monguio R. Medicaid provisions and the US mental health industry composition. J Ment Health. 2014 Dec; 23(6):312-6.
Pellegrini LC, Rodriguez-Monguio R, Qian J. The US healthcare workforce and the labor market effect on healthcare spending and health outcomes. Int J Health Care Finance Econ. 2014 Jun; 14(2):127-41.
Rodriguez-Monguio R, Spielberger K, Seoane-Vazquez E. Examination of risk evaluation and mitigation strategies and drug safety in the US. Res Social Adm Pharm. 2014 Jan-Feb; 10(1):232-8.
Jasinski CF, Rodriguez-Monguio R, Tonyushkina K, Allen H. Healthcare cost of type 1 diabetes mellitus in new-onset children in a hospital compared to an outpatient setting. BMC Pediatr. 2013 Apr 15; 13:55.
Nguyen D, Seoane-Vazquez E, Rodriguez-Monguio R, Montagne M. Changes in FDA enforcement activities following changes in federal administration: the case of regulatory letters released to pharmaceutical companies. BMC Health Serv Res. 2013 Jan 22; 13:27.
Outterson K, Powers JH, Seoane-Vazquez E, Rodriguez-Monguio R, Kesselheim AS. Approval and withdrawal of new antibiotics and other antiinfectives in the U.S., 1980-2009. J Law Med Ethics. 2013; 41(3):688-96.
Zhang H, Rodriguez-Monguio R. Racial disparities in the risk of developing obesity-related diseases: a cross-sectional study. Ethn Dis. 2012; 22(3):308-16.
Visaria J, Seoane-Vazquez E, Szeinbach SL, Rodriguez-Monguio R. Comparing the cost of community pharmacy and mail-order pharmacy in a US retirement system. Int J Health Plann Manage. 2012 Jan-Mar; 27(1):e41-50.
Qureshi ZP, Seoane-Vazquez E, Rodriguez-Monguio R, Stevenson KB, Szeinbach SL. Market withdrawal of new molecular entities approved in the United States from 1980 to 2009. Pharmacoepidemiol Drug Saf. 2011 Jul; 20(7):772-7.
Seoane-Vazquez E, Rodriguez-Monguio R. Access to essential drugs in Guyana: a public health challenge. Int J Health Plann Manage. 2010 Jan-Mar; 25(1):2-16.
Rodriguez-Monguio R, Seoane-Vazquez E. Patent life of antiretroviral drugs approved in the US from 1987 to 2007. AIDS Care. 2009 Jun; 21(6):760-8.
Seoane-Vazquez E, Rodriguez-Monguio R, Szeinbach SL, Beyer A, Visaria J. Analysis of the impact of the Uruguay Round Agreements Act on pharmaceutical patents. Food Drug Law J. 2009; 64(1):171-81.
Seoane-Vazquez E, Rodriguez-Monguio R, Szeinbach SL, Visaria J. Incentives for orphan drug research and development in the United States. Orphanet J Rare Dis. 2008 Dec 16; 3:33.
Seoane-Vazquez E, Rodriguez-Monguio R. Endoscopy-related infection: relic of the past? Curr Opin Infect Dis. 2008 Aug; 21(4):362-6.
Valluri S, Seoane-Vazquez E, Rodriguez-Monguio R, Szeinbach SL. Drug utilization and cost in a Medicaid population: a simulation study of community vs. mail order pharmacy. BMC Health Serv Res. 2007 Jul 30; 7:122.
Seoane-Vazquez E, Rodriguez-Monguio R, Visaria J, Carlson A. Endoscopy-related infections and toxic reactions: an international comparison. Endoscopy. 2007 Aug; 39(8):742-6.
Seoane-Vazquez E, Rodriguez-Monguio R. Negotiating antiretroviral drug prices: the experience of the Andean countries. Health Policy Plan. 2007 Mar; 22(2):63-72.
Seoane-Vazquez E, Rodriguez-Monguio R, Visaria J, Carlson A. Exogenous endoscopy-related infections, pseudo-infections, and toxic reactions: clinical and economic burden. Curr Med Res Opin. 2006 Oct; 22(10):2007-21.
Rodríguez-Monguió R, Rovira J, Seoane-Vázquez E. Analysis of the World Bank's pharmaceutical lending. Health Policy. 2007 Apr; 81(1):102-16.
Rodríguez-Monguió R, Antoñanzas Villar F. Healthcare rationing in Spain: framework, descriptive analysis and consequences. Pharmacoeconomics. 2006; 24(6):537-48.
Rodríguez-Monguió R, Otero MJ, Rovira J. Assessing the economic impact of adverse drug effects. Pharmacoeconomics. 2003; 21(9):623-50.