Nadav Ahituv, PhD

What I do

My research focuses on understanding how nucleotide variation in gene regulatory elements can lead to human disease and other phenotypes.

Departmental research area

My research expertise

functional genomics, gene regulation, human genetics, mouse genetic engineering, gene therapy, obesity, neurodevelopment, cancer diagnosis

Professional background


The Ahituv lab is focused on identifying gene regulatory elements and linking nucleotide variation within them to various phenotypes including morphological differences between species, drug response and human disease. In addition, our lab is developing massively parallel reporter assays (MPRAs) that allow for high-throughput functional characterization of gene regulatory elements and the use of gene regulatory elements as therapeutic targets or disease diagnostic markers.

Research keywords

  • enhancers
  • limb malformations
  • autism
  • pharmacogenomics
  • epilepsy
  • noncoding DNA
  • obesity
  • mouse models
  • comparative genomics
  • Human genetics
  • gene regulation
  • genomics
  • scoliosis
  • Zebrafish
  • scoliosis
  • Syndactyly
  • Exons
  • Congenital Limb Deformities
  • Regulatory Elements, Transcriptional
  • Gene Expression Regulation, Developmental
  • transcription factors
  • Enhancer Elements, Genetic
  • Gene Expression Regulation
  • Promoter Regions, Genetic
  • Chiroptera
  • Regulatory Sequences, Nucleic Acid
  • Hand Deformities, Congenital
  • Human Genome
  • Sequence Analysis, DNA