UCSF

Tagged: Protein Conformation

DeGrado receives Protein Society’s Stein and Moore Award

William DeGrado, PhD, faculty member in the School’s Department of Pharmaceutical Chemistry, has been named the 2015 recipient of The Protein Society’s Stein and Moore Award.

The award is given annually by the international society “to recognize eminent leaders in protein science who have made sustained high-impact research contributions to the field.”

James Fraser, PhD

Fraser
Associate Professor

I am a biophysicist. My research is focused on discovering the macromolecular structure and dynamics of proteins—defining conformational states essential for function and understanding transitions between these states.

Tanja Kortemme, PhD

Kortemme
Professor

My research seeks to invent approaches to engineer new biological functions at multiple scales, ranging from atomic details to macromolecular machines to cellular processes. By building new functions through a combination of computational design and experimental engineering, I also hope to learn how molecular design principles shape systems-level properties and, ultimately, organismal fitness.

Matt Jacobson, PhD

Jacobson
Professor and Department Chair

Research in my lab focuses on atomic-level mechanisms of protein regulation, protein-ligand interactions, and computer-aided drug design. My approach is to employ physics-based energy models for predictive protein modeling. Projects in my lab combine algorithm development and biological applications.

Andrej Sali, PhD

Sali
Professor

I am interested in the structure, function, and evolution of proteins and their assemblies. As Associate Dean of Research, I advise the dean and School leaders on research issues and opportunities and represent the School to campus research decision makers and on research-related campus committees.