UCSF

Tagged: enhancers

Nadav Ahituv study provides new insights into enhancer gene regulation

Research led by UCSF scientists has provided fresh insight into the operation of DNA sequences in the genome that regulate gene expression.

The new study looked at the effects of inserting nearly 5,000 synthetic regulatory element sequences into mice as well as human liver cells. Specifically, these were enhancers, snippets of DNA which, when bound by protein molecules called transcription factors, contribute to gene activation.

Nadav Ahituv, PhD

Ahituv
Professor

My research focuses on understanding how nucleotide variation in gene regulatory elements can lead to human disease and other phenotypes. 

Child’s illness fuels lab team’s search for early-life epilepsy diagnostics

The lab of UCSF School of Pharmacy faculty member Nadav Ahituv, PhD, studies how abnormalities in DNA segments that control the activity of genes could lead to diseases.