Research

Chemicals used to turn skin cells into heart and brain cells

Thu Apr 28, 2016

Sheng Ding, PhD (center), with Deepak Srivastava, MD (right), co-senior author of Science study, and Yadong Huang, MD, PhD (left), co-senior author Cell Stem Cell study.

In a major breakthrough, scientists at the Gladstone Institutes, led by UCSF School of Pharmacy faculty member Sheng Ding, PhD, have transformed skin cells into heart and brain cells using combinations of chemicals.

Pharmacy Alumni Weekend report

Wed Apr 27, 2016

Scientists find new way to inhibit growth of tuberculosis-causing bacterium

Mon Apr 18, 2016

Many Americans say higher prices don’t mean better healthcare

Mon Apr 18, 2016

Crean un riñón bio artificial [Create a bioartificial kidney]

Fri Apr 1, 2016

UCSF School of Pharmacy leads in NIH funding for 36th year in a row

Thu Mar 31, 2016

UCSF News

For the 36th consecutive year, the UCSF School of Pharmacy has received more funding from the National Institutes of Health (NIH) than any other pharmacy school in the United States.

Scientists investigate the weird genetics of bat wings

Mon Mar 28, 2016

Ahituv Lab research finds how bats grow wings, with implications for human limb development

Mon Mar 28, 2016

Mandy K. Mason, University of Cape Town

Natal long-fingered bat embryo (Miniopterus natalensis) stained to highlight bone (red) and cartilage (blue).

Researchers in the laboratory of UCSF School of Pharmacy faculty member Nadav Ahituv, PhD, study the roles of gene regulatory elements—DNA segments that tell genes when, where, and to what extent to turn on and off—including in human conditions ranging from limb malformations to epilepsy and autism.

Fragment-based discovery: using smaller molecules to solve larger challenges

Thu Mar 24, 2016

ChemMedChem, 28 JAN 2016

Protease enzymes of the Kaposi’s sarcoma-associated herpesvirus (KSHV Pr) require two monomer proteins to combine into a dimer in order to activate. Dotted black box is the protein-protein interface targeted for disruption by Craik Lab researchers. (Colored balls represent amino acids—methionines—labeled to help determine if screened fragments inhibit dimerization.)

To discover new drugs and chemical probes, researchers have traditionally screened small molecules—small enough by weight to pass through cell membranes.

Handful of Biologists Went Rogue and Published Directly to Internet

Mon Mar 21, 2016

Categories: Research