Topics and Expertise: virtual screening

Shoichet receives DeLano Award for Computational Biosciences

Thu Dec 1, 2016

Robert Rizzo

Graphic depiction of a typical DOCK setup used toward the discovery of a potential disease inhibitor—in this case, testing compounds for binding to an HIV protein.

Brian Shoichet, PhD, faculty member in the School’s Department of Pharmaceutical Chemistry, has been named the 2017 recipient of the DeLano Award for Computational Biosciences.

Shoichet study sheds light on “dark” cell receptors, potential drug targets

Mon Nov 9, 2015

Brian Shoichet, PhD

More than a quarter of all drugs work by targeting one of a large family of proteins called G-protein-coupled receptors (GPCRs). Hundreds of different GPCRs are embedded in cell membranes, converting stimuli from the outside world—neurotransmitters, hormones, even light—into intracellular signals...