Topics and Expertise: Small Molecule Discovery Center (SMDC)

A new vision for the Small Molecule Discovery Center

Wed May 1, 2024
Hart and Arkin.

Charles Hart, PhD, and Michelle Arkin, PhD

Charles Hart, PhD, director of the Catalyst Program, joins Department of Pharmaceutical Chemistry Chair Michelle Arkin in the center’s ongoing collaboration with academics, government labs, and pharmaceutical companies to develop drug leads that address unmet medical needs.

Arkin named next chair of Department of Pharmaceutical Chemistry

Wed Nov 18, 2020
Arkin
Elisabeth Fall

Michelle Arkin, PhD

Arkin’s appointment to bolster collaborations between academia and industry for drug discovery.

Arkin receives Ono Pharma Foundation Breakthrough Science Initiative Award

Fri Aug 31, 2018
Arkin
Elisabeth Fall

Michelle Arkin, PhD

Michelle Arkin, PhD, has received the 2018 Breakthrough Science Initiative Award from the Ono Pharma Foundation to study a class of proteins, called 14-3-3 proteins, known to be involved in various cancers, with the ultimate goal of enabling discoveries that lead to new ways to treat cancer.

UCSF School of Pharmacy joins data-sharing partnership to speed cancer drugs

Thu Nov 2, 2017
supercomputers
Lawrence Livermore National Laboratory

A supercomputer in the Lawrence Livermore National Laboratory will be used in Project ATOM, a new public-private project that aims to speed discovery of new drug therapies.

A pioneering public/private consortium is poised to turn the marathon of drug discovery into a team relay, maybe even a short one.

Wells elected member of American Academy of Arts and Sciences

Wed Apr 22, 2015
Wells
Elisabeth Fall

James Wells, PhD

James Wells, PhD, chair of the School’s Department of Pharmaceutical Chemistry, has been elected as a member of the 2015 class of the American Academy of Arts and Sciences.

New ways to tackle cancer-causing virus, eye disease win CTSI funding awards

Fri Aug 31, 2012
Craik and Desai.
© majedphoto.com

Charles S. Craik, PhD and Tejal Desai, PhD

A promising new way to fight human herpes viruses and a drug delivery device to better treat a major cause of blindness have won development funding from UCSF’s Clinical and Translational Science Institute (CTSI).

Teaching old drugs new tricks at the Small Molecule Discovery Center: arthritis drug could treat dysentery

Thu May 24, 2012
Entamoeba histolytica in cyst form
CDC/Dr. George Healy

Entamoeba histolytica in cyst form

The UCSF School of Pharmacy’s Small Molecule Discovery Center (SMDC) provided a key assist to researchers seeking to repurpose existing drugs to treat the worldwide scourge of amoebic dysentery.

Drugs screened for effects on key transporters, risk of dangerous interactions

Tue Nov 8, 2011
diagram

UCSF scientists are studying key drug transporters that play roles in drug absorption and elimination. Shown here: OCT2 and others in the membrane of cells in the kidney tubules (at right). The urine collecting tubules interface with capillaries (at left) to remove substances such as medications and environmental toxins from the blood.

To reduce the risk of toxic drug interactions, UCSF's Kathy Giacomini, PhD, and colleagues are screening thousands of prescription drugs, testing how much they inhibit key proteins in kidney and liver cell

UCSF technology used to trigger cell death becomes basis of company’s cancer therapy research and development

Thu Jul 8, 2010
Wells
© majedphoto.com

James Wells, PhD

A technology developed in the laboratory of James Wells, PhD, chair of the Department of Pharmaceutical Chemistry, UCSF School of Pharmacy, will drive a new approach to cancer treatment that s

Small Molecule Discovery Center and Genentech partner in drug discovery

Fri Feb 19, 2010
UCSF's Small Molecule Discovery Center (SMDC) announced on February 18, 2010 that it has signed its first major industry partnership agreement since the SMDC was founded in 2005. The agreement is with Genentech, Inc.

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