Matt Jacobson, PhD

Department Chair and Professor
Phone: +1 415 514-9811
Fax: +1 415 502-4690
1700 4th St, Rm 408E
UCSF Box 2540
San Francisco, CA 94158
United States

What I do

Research in my lab focuses on atomic-level mechanisms of protein regulation, protein-ligand interactions, and computer-aided drug design. My approach is to employ physics-based energy models for predictive protein modeling. Projects in my lab combine algorithm development and biological applications.

Departmental research area

My research expertise

computer-aided drug design, allostery, post-translational protein modification, protein structure and dynamics


PhD, Physical Chemistry, Massachusetts Institute of Technology (MIT), 1999
BS, Chemistry, Stanford University, 1993


Dr. Jacobson’s research interests are in the area of computational structural biology and computer-aided drug design.