Matt Jacobson, PhD

1700 4th St, Rm 408E
UCSF Box 2540
San Francisco, CA 94158
United States

What I do

Research in my lab focuses on atomic-level mechanisms of protein regulation, protein-ligand interactions, and computer-aided drug design. My approach is to employ physics-based energy models for predictive protein modeling. Projects in my lab combine algorithm development and biological applications.

Departmental research area

My research expertise

computer-aided drug design, allostery, post-translational protein modification, protein structure and dynamics

Professional background


Dr. Jacobson’s research interests are in the area of computational structural biology and computer-aided drug design.

Research keywords

  • Lipoxygenase Inhibitors
  • computational biology
  • Piebaldism
  • Molecular Docking Simulation
  • Enzymes
  • Computer Simulation
  • Protein Conformation
  • Arachidonate 12-Lipoxygenase
  • Molecular Dynamics Simulation
  • Molecular Models
  • Phosphopyruvate Hydratase
  • proteins
  • Alkyl and Aryl Transferases
  • Arachidonate 15-Lipoxygenase
  • Cell Membrane Permeability