Tagged: Molecular Models

James Fraser, PhD


I am a biophysicist. My research is focused on discovering the macromolecular structure and dynamics of proteins—defining conformational states essential for function and understanding transitions between these states.

Tanja Kortemme, PhD


My research seeks to invent approaches to engineer new biological functions at multiple scales, ranging from atomic details to macromolecular machines to cellular processes. By building new functions through a combination of computational design and experimental engineering, I also hope to learn...

Brian Shoichet, PhD


Our lab develops new methods for drug discovery, adopting two strategies to do so. On the one hand, we reduce biology to its molecular components, and seek to change how these fit together using synthetic molecules we design. On the other hand, we investigate how the biological molecules operate...

Tack Kuntz, PhD

Professor Emeritus

Since retiring, I serve as a consultant for current Department faculty.

Thomas James, PhD


I retired from full-time service at UCSF at the end of June, 2012. However, I went on Recall status a month later to do research, which diminishes each year. I needed to finish some projects that were still funded via grants during the initial year and continue with another funded project...

Matt Jacobson, PhD


Research in my lab focuses on atomic-level mechanisms of protein regulation, protein-ligand interactions, and computer-aided drug design. My approach is to employ physics-based energy models for predictive protein modeling. Projects in my lab combine algorithm development and biological...

Tom Ferrin, PhD


My lab develops software tool for visualizing and analyzing molecular structures at scales ranging from the atomic to the supramolecular.

William DeGrado, PhD


My research focuses on small molecule and protein design as an approach to understanding macromolecule structure and function.

Andrej Sali, PhD

Associate Dean and Professor

I am interested in the structure, function, and evolution of proteins and their assemblies. As associate dean of research, I advise the dean and School leaders on research issues and opportunities and represent the School to campus research decision makers and on research-related campus committees.