UCSF

Tagged: drug resistance

Combination drug therapy overcomes drug-resistant lung cancer in the lab

Many types of lung cancer thwart even the most targeted of therapies due to drug resistance, but a group of UCSF scientists led by Sourav Bandyopadhyay, PhD, have now shown that adding a second drug into treatment regimens can overcome this resistance in lab-grown, lung cancer cell lines.

Renslo Lab develops new type of targeted chemotherapy that proves effective in mice

Research in the lab of UCSF School of Pharmacy faculty member Adam Renslo, PhD, has developed a new way of selectively targeting cancer cells with drugs. In experiments with mice, the new approach allowed for the delivery of fifty times higher doses of chemotherapy to tumors while avoiding toxic...

Research: pediatric meningitis dosing; cancer drug resistance; gene-testing economics

Computer models provide optimal dosing for pediatric TB meningitis

Aweeka co-leads new study of drugs to prevent malaria in young children, pregnant women

Francesca Aweeka, PharmD, a faculty member in the School’s Department of Clinical Pharmacy, will co-lead a new five-year, $3.4 million study funded by the National Institutes of Health (NIH) to address one of the world’s most vexing health problems—preventing malaria, especially in the most...

Deanna Kroetz, PhD

Professor

My research seeks to understand the contribution of genetic variation to drug toxicity, to identify genetic biomarkers that can be used to guide effective use of drugs in the treatment of cancer and HIV, and to use genetics to unravel the molecular basis of drug-induced toxicity.

Antimicrobial drug management program succeeds through teamwork

Increasing resistance to antimicrobial drugs and a shortage of new antimicrobial drugs call for new ways to use them wisely. This is especially true in hospitals and medical centers where bacteria are prominent and can be easily spread.