UCSF

Tagged: computational modeling

Amelia Deitchman, PharmD, PhD

Assistant Professor

My research seeks to inform novel therapeutic strategies to cure HIV through better understanding of pharmacokinetics and pharmacodynamics of individual and combinations of candidate drugs. Based out of the UCSF Drug Research Unit (DRU), I work with a multidisciplinary team of clinicians-scientists...

Computer models speed UCSF scientists toward psychiatric drug discoveries

For decades, scientists have wanted to be able to study dopamine receptors one by one. The brain’s dopamine receptors are responsible for a variety of behaviors, such as reward seeking, and are also involved in psychiatric illnesses like schizophrenia.

Shoichet study sheds light on “dark” cell receptors, potential drug targets

More than a quarter of all drugs work by targeting one of a large family of proteins called G-protein-coupled receptors (GPCRs). Hundreds of different GPCRs are embedded in cell membranes, converting stimuli from the outside world—neurotransmitters, hormones, even light—into intracellular signals...