Research

Shoichet is the new director of the QB3 at UCSF

Tue Apr 3, 2012

Brian Shoichet, PhD

Computational chemist Brian Shoichet, PhD, a faculty member in the Department of Pharmaceutical Chemistry, UCSF School of Pharmacy, is the new director of the California Institute for Quantitative Biosciences

The HIV pharmacist: helping patients pick and stick with lifesaving drugs

Wed Feb 22, 2012

Jennifer Cocohoba, PharmD

How do you convince patients who feel fine to take medicines that can have major side effects?

How can you help them stay on their lifesaving daily medications for years to come despite the obstacle course of everyday life?

Study finds including unpublished FDA data alters drug effectiveness outcomes

Fri Jan 20, 2012

Lisa Bero, PhD

Every year U.S. drug regulators approve dozens of new medicines as “safe and effective,” but just how effective are they? How well do they alleviate specific aspects of illness, whether light sensitivity from migraine headaches or itching from eczema?

Partners in D program wins AACP Award for Student Community Service

Mon Jan 9, 2012

Partners in D student pharmacists counsel seniors.

Partners in D, the innovative program in which UCSF student pharmacists help both underserved seniors and fellow health professionals maximize the complex Medicare Part D drug benefit, has won a national award for community service.

Soller defines the roadmap for Rx-to-OTC switches

Tue Nov 29, 2011

William Soller, PhD

If you are a pharmaceutical company seeking to switch your prescription medication to one sold directly to consumers—as an over-the-counter or OTC drug—William Soller, PhD, has your road map.

Computer models to predict drug clearance by liver cells show promise

Tue Nov 22, 2011

A schematic diagram of the mechanisms built into each cell in the in silico hepatocyte cultures. Checkmarks indicate events affected by the physical and chemical properties of a specific virtual drug object. For example, depending on such properties a given drug bound to an enzyme can have a different probability of being metabolized or released. (Source: Drug Metab Dispos. 2011 Oct;39(10):p. 1910-20)

A holy grail of drug discovery is to answer key questions about potential new drugs less by experiments in petri dishes and lab animals and more by faster, cheaper engineering efforts using predictive computer models.

Consortium inventing medical devices for children gets new funding

Thu Nov 10, 2011

Shuvo Roy, PhD

A two-year-old, cross-disciplinary effort to invent new medical devices for children, co-founded by bioengineer Shuvo Roy, PhD, has received a two-year $1 million grant from the U.S. Food and Drug Administration (FDA) to expand its work.

Bero heads new WHO center studying, promoting global access to vital drugs

Wed Nov 9, 2011

Cindy Chew

Lisa Bero, PhD

The office of Lisa Bero, PhD, on UCSF’s Laurel Heights campus has long been a key portal between the School of Pharmacy and the world at large, including countries where billions of people cannot get even the most vital life-saving drugs.

Drugs screened for effects on key transporters, risk of dangerous interactions

Tue Nov 8, 2011

UCSF scientists are studying key drug transporters that play roles in drug absorption and elimination. Shown here: OCT2 and others in the membrane of cells in the kidney tubules (at right). The urine collecting tubules interface with capillaries (at left) to remove substances such as medications and environmental toxins from the blood.

To reduce the risk of toxic drug interactions, UCSF's Kathy Giacomini, PhD, and colleagues are screening thousands of prescription drugs, testing how much they inhibit key proteins in kidney and liver cell

In-flight programming features bioartificial kidney

Fri Oct 21, 2011

BriYYZ

, CC BY-SA 2.0

Passengers who travel on American Airlines from September through October 2011 will learn about the surgically implantable bioartificial kidney being developed at UCSF as a permanent solution to end stage renal disease.

Categories: Research