B Joseph Guglielmo, PharmD

B. Joseph Guglielmo, PharmD, is a pharmacist, clinical scientist, teacher, and international expert in the evidence-based use of antimicrobials to treat infections. He has served as interim dean, then as dean of the UCSF School of Pharmacy, since 2012 and holds the Troy C. Daniels Distinguished Professorship in Pharmaceutical Sciences.

He is widely known as an advocate for therapeutics-related research, from basic science to health policy research. As chair of the School's Department of Clinical Pharmacy, Guglielmo oversaw a 40 percent increase in the Department of Clinical Pharmacy’s faculty research funding from 2006 to 2012, including grants from the National Institutes of Health. During that period an increasing number of the department’s clinical faculty members received National Institutes of Health “K” awards, designed to develop clinical research scientists as independent investigators, as well as “R” awards that fund specific research projects.

He created the Department of Clinical Pharmacy-run Medication Outcomes Center in 2007 to research and improve medication use in the UCSF Medical Center and beyond. In the 1980s he developed the UCSF Medical Center Antimicrobial Stewardship Program to study and improve antimicrobial use in the UCSF Medical Center, with the goal of decreasing antimicrobial resistance. This evidence-based program was one of the earliest programs of its kind in the United States.

As patients seek new and cost-effective health care with increasingly complicated disease states and medications, Guglielmo advocates for research on new ways for pharmacists to care for patients, especially in the community. He also supports strong relationships among clinical scientists and their upstream basic and translational scientist colleagues, as demonstrated through his own collaborations. Guglielmo has been actively involved in the UCSF Clinical and Translational Science Institute (CTSI) from its inception and during its renewal; he has also served as the long-term associate director of the CTSI Mentor Development Program.

His personal research agenda involves the safe, effective, and appropriate use of antimicrobials, as well as the pharmacoepidemiology and pharmacokinetics of anti-infective agents. He is the author of more than 110 peer-reviewed papers, the majority related to anti-infective agents.

He believes that the most important clinical research is shaped through the researcher’s own clinical experiences. Together with his administrative, research, and teaching responsibilities, he practices in the UCSF Medical Center, where he is an infectious diseases pharmacist supporting the UCSF Medical Center Antimicrobial Stewardship Program and serving on the Infectious Diseases Consult Service team. These experiences continue to provide the background for important hypothesis-centered research on the safe, effective use of antimicrobials. Beyond the hospital, Guglielmo developed clinical pharmacy services for UCSF's HIV/AIDS program, specifically for the HIV Women's Program and the Men of Color Program.

Guglielmo has taught doctor of pharmacy students, pharmacy residents and fellows, medical students and residents, and infectious diseases fellows for decades, and has mentored infectious diseases specialty pharmacist residents and fellows continuously since 1986. He has also mentored a number of international scholars, including Fogarty fellows. He is the recipient of many teaching awards, including the UCSF Lifetime Achievement in Mentoring Award, Resident Preceptor of the Year Awards, UCSF School of Pharmacy Long Teaching Awards, and the Academic Senate Distinction in Teaching Award.

Guglielmo is the long-term editor of Applied Therapeutics: The Clinical Use of Drugs and the Handbook of Applied Therapeutics. He lectures worldwide on the safe, effective use of antimicrobials and other medications. Guglielmo earned a PharmD degree from the University of Southern California in 1978 and completed a pharmacy practice residency at UCSF in 1979, before joining the UCSF School of Pharmacy faculty.