Sheng Ding, PhD

Phone: +1 415 734-2717
555 Mission Bay Blvd South, Rm 001
San Francisco, CA 94158
United States


What I do

My research focuses on discovering and characterizing novel small molecules that can control stem cell maintenance, activation, differentiation, and reprogramming in various tissue types.

Departmental research area

My research expertise

stem cell biology, Chemical Biology, Drug Discovery, medicinal chemistry, high-throughput screening (HTS)

Professional background


Dr. Sheng Ding is currently William K. Bowes, Jr. Distinguished Investigator and Professor at Gladstone Institute of Cardiovascular Disease, and Department of Pharmaceutical Chemistry, University of California San Francisco. He obtained his B.S. in chemistry with honors from Caltech in 1999, and a Ph.D. in chemistry from The Scripps Research Institute in 2003. Before moving to Gladstone/UCSF in early 2011, Ding was an Assistant Professor and then Associate Professor of Chemistry at Scripps from 2003 to 2011. Dr. Ding has pioneered on developing and applying innovative chemical approaches to stem cell biology and regeneration, with a focus on discovering and characterizing novel small molecules that can control various cell fate/function, including stem cell maintenance, activation, differentiation and reprogramming in various developmental stages and tissues. Ding has published over 100 research articles, reviews and book chapters, and made several seminal contributions to the stem cell field. Ding is a cofounder of Fate Therapeutics and Stemgent.

Research keywords

  • Octamer Transcription Factor-3
  • Adipose Tissue, Brown
  • Induced Pluripotent Stem Cells
  • Culture Media
  • Cell Lineage
  • Neural Stem Cells
  • Fibroblasts
  • regenerative medicine
  • Stem Cells
  • cellular reprogramming
  • Pluripotent Stem Cells
  • Cell Transdifferentiation
  • Small Molecule Libraries
  • Myoblasts, Cardiac
  • Cellular Reprogramming Techniques