Lawrence Lin, PhD

Vice Dean and Chief of Staff
Dean's Office
Lin
[email protected]
Phone: +1 415 476-5216
513 Parnassus Avenue, MSB, Rm 126
UCSF Box 0403
San Francisco, CA 94143
United States

Links

UCSF Profiles

Affiliations

UCSF centers, institutes, and research programs

Executive Director, UCSF-Stanford Center of Excellence in Regulatory Science and Innovation (CERSI)

What I do

I serve as the Dean’s strategic advisor, provide oversight and guidance to high priority initiatives, and lead key strategic cross-functional and transformational projects. I help to coordinate the Dean’s activities to maximize productivity and impact and frequently join or represent the Dean at various meetings, committees, and events.

As part of the Dean’s Office, I work closely with the School of Pharmacy leadership team to develop and implement long-term and short-term strategic and operational plans. I also serve as the Executive Director of the UCSF-Stanford Center of Excellence in Regulatory Science and Innovation (CERSI).

Professional background

Degrees

PhD, Pharmaceutical Sciences and Pharmacogenomics, University of California, San Francisco
BS, Biological Sciences with additional majors in Anthropology and History, Carnegie Mellon University

Biography

Lawrence Lin, PhD, is Vice Dean and Chief of Staff in the UCSF School of Pharmacy. In this role, he is the senior strategic advisor to the Dean, provides oversight and guidance to high priority initiatives, and leads key strategic cross-functional and transformational projects. Dr. Lin frequently joins or represents the Dean at various meetings, committees, and events and works closely with school leadership to develop and implement long-term and short-term strategic and operational plans. In addition, he serves as the Executive Director of the UCSF-Stanford Center of Excellence in Regulatory Science and Innovation (CERSI), an FDA-funded regulatory science center based at UCSF and Stanford University that seeks to advance regulatory science through collaborative research, education, and outreach activities. Before joining the School of Pharmacy Dean’s Office, Dr. Lin served in a variety of scientific and operational roles at UCSF for over ten years. Dr. Lin received a B.S. in Biological Sciences with additional majors in Anthropology and History from Carnegie Mellon University, and his Ph.D. in Pharmaceutical Sciences and Pharmacogenomics from the University of California, San Francisco.

Research keywords

  • Activating Transcription Factor 3
  • 3-Iodobenzylguanidine
  • Organic Anion Transporters
  • Vesicular Monoamine Transport Proteins
  • Phenylalanine
  • Ribosome Subunits, Large, Eukaryotic
  • Ataxia Telangiectasia Mutated Proteins
  • Molecular Targeted Therapy
  • Drugs, Investigational
  • Drug Costs
  • Norepinephrine Plasma Membrane Transport Proteins
  • Large Neutral Amino Acid-Transporter 1
  • Hydroxamic Acids
  • Membrane Transport Proteins
  • Carboxylic Acids

Publications

Wilson JL, Cheung KWK, Lin L, Green EAE, Porrás AI, Zou L, Mukanga D, Akpa PA, Darko DM, Yuan R, Ding S, Johnson WCN, Lee HA, Cooke E, Peck CC, Kern SE, Hartman D, Hayashi Y, Marks PW, Altman RB, Lumpkin MM, Giacomini KM, Blaschke TF. Scientific considerations for global drug development. Sci Transl Med. 2020 07 29; 12(554).
Wilson L, Lin L, Singh K. The Patient Perspective: Putting the Patient at the Center of the Translational Innovation Process. Clin Pharmacol Ther. 2020 01; 107(1):82-84.
Giacomini KM, Lin L, Altman RB. Research Projects Supported by the University of California, San Francisco-Stanford Center of Excellence in Regulatory Science and Innovation. Clin Pharmacol Ther. 2019 04; 105(4):815-818.
Relling MV, Krauss RM, Roden DM, Klein TE, Fowler DM, Terada N, Lin L, Riel-Mehan M, Do TP, Kubo M, Yee SW, Johnson GT, Giacomini KM. New Pharmacogenomics Research Network: An Open Community Catalyzing Research and Translation in Precision Medicine. Clin Pharmacol Ther. 2017 Dec; 102(6):897-902.
Khuri N, Zur AA, Wittwer MB, Lin L, Yee SW, Sali A, Giacomini KM. Computational Discovery and Experimental Validation of Inhibitors of the Human Intestinal Transporter OATP2B1. J Chem Inf Model. 2017 06 26; 57(6):1402-1413.
Luizon MR, Eckalbar WL, Wang Y, Jones SL, Smith RP, Laurance M, Lin L, Gallins PJ, Etheridge AS, Wright F, Zhou Y, Molony C, Innocenti F, Yee SW, Giacomini KM, Ahituv N. Genomic Characterization of Metformin Hepatic Response. PLoS Genet. 2016 Nov; 12(11):e1006449.
Zur AA, Chien HC, Augustyn E, Flint A, Heeren N, Finke K, Hernandez C, Hansen L, Miller S, Lin L, Giacomini KM, Colas C, Schlessinger A, Thomas AA. LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substrates. Bioorg Med Chem Lett. 2016 10 15; 26(20):5000-5006.
Augustyn E, Finke K, Zur AA, Hansen L, Heeren N, Chien HC, Lin L, Giacomini KM, Colas C, Schlessinger A, Thomas AA. LAT-1 activity of meta-substituted phenylalanine and tyrosine analogs. Bioorg Med Chem Lett. 2016 06 01; 26(11):2616-2621.
Temple W, Mendelsohn L, Kim GE, Nekritz E, Gustafson WC, Lin L, Giacomini K, Naranjo A, Van Ryn C, Yanik GA, Kreissman SG, Hogarty M, Matthay KK, DuBois SG. Vesicular monoamine transporter protein expression correlates with clinical features, tumor biology, and MIBG avidity in neuroblastoma: a report from the Children's Oncology Group. Eur J Nucl Med Mol Imaging. 2016 Mar; 43(3):474-481.
Yee SW, Lin L, Merski M, Keiser MJ, Gupta A, Zhang Y, Chien HC, Shoichet BK, Giacomini KM. Prediction and validation of enzyme and transporter off-targets for metformin. J Pharmacokinet Pharmacodyn. 2015 Oct; 42(5):463-75.
Lin L, Yee SW, Kim RB, Giacomini KM. SLC transporters as therapeutic targets: emerging opportunities. Nat Rev Drug Discov. 2015 Aug; 14(8):543-60.
Gamalinda M, Ohmayer U, Jakovljevic J, Kumcuoglu B, Woolford J, Mbom B, Lin L, Woolford JL. A hierarchical model for assembly of eukaryotic 60S ribosomal subunit domains. Genes Dev. 2014 Jan 15; 28(2):198-210.
Drake KA, Torgerson DG, Gignoux CR, Galanter JM, Roth LA, Huntsman S, Eng C, Oh SS, Yee SW, Lin L, Bustamante CD, Moreno-Estrada A, Sandoval K, Davis A, Borrell LN, Farber HJ, Kumar R, Avila PC, Brigino-Buenaventura E, Chapela R, Ford JG, Lenoir MA, Lurmann F, Meade K, Serebrisky D, Thyne S, Rodríguez-Cintrón W, Sen S, Rodríguez-Santana JR, Hernandez RD, Giacomini KM, Burchard EG. A genome-wide association study of bronchodilator response in Latinos implicates rare variants. J Allergy Clin Immunol. 2014 Feb; 133(2):370-8.