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Adam Abate, PhD
Phone: +1 415 476-9819
Fax: +1 415 514-1028
1700 4th Street, Rm 303C
UCSF Box 2532
San Francisco, CA 94158
United States Links
Affiliations
Education programs
UCSF centers, institutes, and research programs
External affiliations
Technology Founder, Consultant, GnuBIO, Inc.
Founder, Chairman of the Board, Mission Bio
What I do
I use droplet-based microfluidics for directed evolution and massively parallel single cell analysis.
Departmental research area
My research expertise
soft matter physics, droplet-based microfluidics, single cell analysis, genomics, next-gen sequencing prep techniques, PCR-activated cell sorting, directed evolution, enzyme engineering, digital biology
Professional background
Degrees
PhD, Physics of Soft Materials, University of Pennsylvania, 2006
MS, Physics, University of California, Los Angeles, 2004
BA, Physics, Harvard College, Harvard University, 2002
Biography
Dr. Adam Abate is a physicist who brings a unique research program to the campus. His research employs microfluidics for high-throughput biological applications. He has developed microfluidic methods to create emulsions that consist of droplets of very precise and consistent sizes and to manipulate the processing and contents of individual droplets in different ways. The droplets are used to create micro-compartments, which can be loaded with single cells and other active materials, such as drugs, nutrients, and assay reagents. By chaining together different microdevice components, the droplets can be used as tiny "test tubes" for performing chemical and biological reactions. This allows multiple, independent reactions to take place at the rate of thousands per second, while using minuscule amounts of total reagent. Adam is using this approach for directed evolution, genetic sequencing, and cell sorting.
Research keywords
- bioengineering
- directed evolution
- emulsification
- microfluidics
- drug encapsulation
- sequencing
- microparticle synthesis
- droplet-based microfluidics
- soft-condensed matter physics
- high-throughput screening
- granular physics
- Microfluidic Analytical Techniques
- Metabolic Engineering
- Biological Assay
- Sequence Analysis, DNA
- Single-Cell Analysis
- microfluidics
- Emulsions
- DNA Barcoding, Taxonomic
- Nucleic Acids
- Lab-On-A-Chip Devices
- Dimethylpolysiloxanes
- High-Throughput Nucleotide Sequencing
- High-Throughput Screening Assays
- Flow Cytometry
- Polymerase Chain Reaction
1. | New Innovator Award, NIH, 2014-2019 |
2. | CAREER Award, NSF, 2013-2018 |
3. | US-Japan Young Scientist Exchange Program, NSF, NIMS, 2013-2014 |
4. | Stanley A. Marks Scholar, Harvard University, 2000-2002 |
Publications
Pan S, Chang KC, Fernández-Maestre I, Van Haver S, Wereski MG, Bowman RL, Levine RL, Abate AR. PURE-seq identifies Egr1 as a Potential Master Regulator in Murine Aging by Sequencing Long-Term Hematopoietic Stem Cells. bioRxiv. 2024 Aug 14. |
Pan S, Chang KC, Fernández-Maestre I, Van Haver S, Wereski MG, Bowman RL, Levine RL, Abate AR. PURE-seq identifies Egr1 as a Potential Master Regulator in Murine Aging by Sequencing Long-Term Hematopoietic Stem Cells. Res Sq. 2024 Aug 13. |
Yadav P, Ortega JG, Tamaki W, Chien C, Chang KC, Biswas N, Pan S, Nilsson J, Yin X, Bhattacharyya A, Boostanpour K, Jujaray T, Wang J, Tsukui T, Sheppard D, Li B, Maishan M, Taenaka H, Matthay MA, Muramatsu R, Maliskova L, Ghosh A, Eckalbar WL, Molofsky AB, Wolters PJ, Tamaki SJ, Bivona T, Abate AR, Wagner A, Tharp KM, Bhattacharya M. Macrophage-fibroblast crosstalk drives Arg1-dependent lung fibrosis via ornithine loading. bioRxiv. 2024 Jul 31. |
Shin SW, Mudvari P, Thaploo S, Wheeler MA, Douek DC, Quintana FJ, Boritz EA, Abate AR, Clark IC. FIND-seq: high-throughput nucleic acid cytometry for rare single-cell transcriptomics. Nat Protoc. 2024 Jul 22. |
Li X, Xu L, Demaree B, Noecker C, Bisanz JE, Weisgerber DW, Modavi C, Turnbaugh PJ, Abate AR. Microbiome single cell atlases generated with a commercial instrument. bioRxiv. 2024 Mar 16. |
Vasudevan HN, Payne E, Delley CL, John Liu S, Mirchia K, Sale MJ, Lastella S, Nunez MS, Lucas CG, Eaton CD, Casey-Clyde T, Magill ST, Chen WC, Braunstein SE, Perry A, Jacques L, Reddy AT, Pekmezci M, Abate AR, McCormick F, Raleigh DR. Functional interactions between neurofibromatosis tumor suppressors underlie Schwann cell tumor de-differentiation and treatment resistance. Nat Commun. 2024 Jan 12; 15(1):477. |
Sixuan Pan, John Liu, Kanish Mirchia, Emily Payne, Joanna Pak, Kyounghee Seo, Tomoko Ozawa, David Raleigh, Mitchel Berger, Adam Abate, Harish Vasudevan. DDDR-18. SINGLE-CELL FUNCTIONAL GENOMIC ANALYSIS OF PHARMACOLOGIC RESPONSES IN NF1 MUTANT GLIOBLASTOMA REVEALS DISTINCT MECHANISMS OF ACTION FOR MEK AND SHP2 INHIBITION. Neuro-Oncology. 2023 Nov 10; 25(Supplement_5):v109-v109. |
Zhang P, Liu C, Modavi C, Abate A, Chen H. Printhead on a chip: empowering droplet-based bioprinting with microfluidics. Trends Biotechnol. 2024 03; 42(3):353-368. |
Abate A, Li X, Xu L, Demaree B, Noecker C, Bisanz J, Weisgerber D, Modavi C, Turnbaugh P. Microbiome single cell atlases generated with a commercial instrument. Res Sq. 2023 Sep 14. |
Vasudevan HN, Delley C, Chen WC, Mirchia K, Pan S, Shukla P, Aabedi AA, Nguyen MP, Morshed RA, Young JS, Boreta L, Fogh SE, Nakamura JL, Theodosopoulos PV, Phillips J, Hervey-Jumper SL, Daras M, Pike L, Aghi MK, Tsai K, Raleigh DR, Braunstein SE, Abate AR. Molecular Features of Resected Melanoma Brain Metastases, Clinical Outcomes, and Responses to Immunotherapy. JAMA Netw Open. 2023 08 01; 6(8):e2329186. |
Weisgerber DW, Langer K, Servellita V, Xu P, Chiu CY, Abate AR. Viral load quantitation at the point-of-care with shaken digital droplet RT-LAMP. Lab Chip. 2023 07 25; 23(15):3479-3486. |
Peretz CAC, Kennedy VE, Walia A, Delley CL, Koh A, Tran E, Clark IC, Hayford CE, D'Amato C, Xue Y, Fontanez KM, Roy R, Logan AC, Perl AE, Abate A, Olshen A, Smith CC. Multiomic Single Cell Sequencing Identifies Stemlike Nature of Mixed Phenotype Acute Leukemia and Provides Novel Risk Stratification. bioRxiv. 2023 May 18. |
Zhang P, Xu L, Chen H, Abate AR. Flow cytometric printing of double emulsions into open droplet arrays. Lab Chip. 2023 May 16; 23(10):2371-2377. |
Thomas Moragues, Diana Arguijo, Thomas Beneyton, Cyrus Modavi, Karolis Simutis, Adam R. Abate, Jean-Christophe Baret, Andrew J. deMello, Douglas Densmore, Andrew D. Griffiths. Droplet-based microfluidics. Nature Reviews Methods Primers. 2023 Apr 20; 3(1):32. |
Wheeler MA, Clark IC, Lee HG, Li Z, Linnerbauer M, Rone JM, Blain M, Akl CF, Piester G, Giovannoni F, Charabati M, Lee JH, Kye YC, Choi J, Sanmarco LM, Srun L, Chung EN, Flausino LE, Andersen BM, Rothhammer V, Yano H, Illouz T, Zandee SEJ, Daniel C, Artis D, Prinz M, Abate AR, Kuchroo VK, Antel JP, Prat A, Quintana FJ. Droplet-based forward genetic screening of astrocyte-microglia cross-talk. Science. 2023 03 10; 379(6636):1023-1030. |
Clark IC, Fontanez KM, Meltzer RH, Xue Y, Hayford C, May-Zhang A, D'Amato C, Osman A, Zhang JQ, Hettige P, Ishibashi JSA, Delley CL, Weisgerber DW, Replogle JM, Jost M, Phong KT, Kennedy VE, Peretz CAC, Kim EA, Song S, Karlon W, Weissman JS, Smith CC, Gartner ZJ, Abate AR. Microfluidics-free single-cell genomics with templated emulsification. Nat Biotechnol. 2023 Nov; 41(11):1557-1566. |
Clark IC, Mudvari P, Thaploo S, Smith S, Abu-Laban M, Hamouda M, Theberge M, Shah S, Ko SH, Pérez L, Bunis DG, Lee JS, Kilam D, Zakaria S, Choi S, Darko S, Henry AR, Wheeler MA, Hoh R, Butrus S, Deeks SG, Quintana FJ, Douek DC, Abate AR, Boritz EA. HIV silencing and cell survival signatures in infected T cell reservoirs. Nature. 2023 02; 614(7947):318-325. |
Clark IC, Wheeler MA, Lee HG, Li Z, Sanmarco LM, Thaploo S, Polonio CM, Shin SW, Scalisi G, Henry AR, Rone JM, Giovannoni F, Charabati M, Akl CF, Aleman DM, Zandee SEJ, Prat A, Douek DC, Boritz EA, Quintana FJ, Abate AR. Identification of astrocyte regulators by nucleic acid cytometry. Nature. 2023 02; 614(7947):326-333. |
I.C. Clark, P. Mudvari, S. Thaploo, S. Smith, M. Abu-Laban, S.G. Deeks, F.J. Quintana, D.C. Douek, A.R. Abate, E.A. Boritz. OP 1.2 – 00157 HIV Silencing and Cell Survival Signatures of HIV-Infected CD4 T Cell Transcriptomes under Antiretroviral Therapy (ART). Journal of Virus Eradication. 2022 Dec 1; 8:100097. |
Zath GK, Sperling RA, Hoffman CW, Bikos DA, Abbasi R, Abate AR, Weitz DA, Chang CB. Rapid parallel generation of a fluorescently barcoded drop library from a microtiter plate using the plate-interfacing parallel encapsulation (PIPE) chip. Lab Chip. 2022 11 22; 22(23):4735-4745. |
Cheryl Peretz, Vanessa E. Kennedy, Anushka Walia, Cyrille Delley, Andrew Koh, Elaine Tran, Iain Clark, Corey Hayford, Yi Xue, Chris D'Amato, Kristina Fontanez, Ritu P. Roy, Adam Olshen, Aaron C. Logan, Alexander E. Perl, Adam Abate, Catherine Smith. Multiomic Single-Cell Sequencing of Mixed Phenotypic Acute Leukemia (MPAL) Reveals Complex Immunophenotypic, Transcriptional, and Genetic Heterogeneity. Blood. 2022 Nov 15; 140(Supplement 1):9146-9147. |
Harish Vasudevan, Cyrille Delley, Alexander Aabedi, Poojan Shukla, Minh Nguyen, Ramin A Morshed, Jacob S Young, Ben Demaree, Devan Diwanji, Shawn L Hervey-Jumper, Lauren Boreta, Shannon Fogh, Jean Nakamura, Philip Theodospoulos, Joanna J Phillips, Mariza Daras, Katy Tsai, Penny Sneed, Manish Aghi, David Raleigh, Steve Braunstein, Adam Abate. BIOM-02. MUTATIONAL ANALYSIS AND SINGLE CELL SEQUENCING OF MELANOMA BRAIN METASTASES REVEALS BRAF STATUS CORRELATES WITH CLINICAL OUTCOME AND DIFFERENTIAL IMMUNE POPULATIONS. Neuro-Oncology. 2022 Nov 14; 24(Supplement_7):vii3-vii4. |
Harish Vasudevan, Emily Payne, Cyrille Delley, Matthew Sale, S John Liu, Sydney Lastella, Calixto-Hope Lucas, Charlotte Eaton, Tim Casey-Clyde, Stephen Magill, William Chen, Alyssa Reddy, Steve Braunstein, Arie Perry, Line Jacques, Melike Pekmezci, Adam Abate, Frank McCormick, David Raleigh. DDDR-06. NEUROFIBROMATOSIS TUMOR SUPPRESSORS COOPERATIVELY DRIVE TUMOR DE-DIFFERENTIATION AND MEK INHIBITOR RESISTANCE IN PERIPHERAL NERVOUS SYSTEM TUMORS. Neuro-Oncology. 2022 Nov 14; 24(Supplement_7):vii99-vii99. |
H. Vasudevan, C. Delley, A. Aabedi, M.P. Nguyen, R.A. Morshed, J.S. Young, B. Demaree, D. Diwanji, S. Hervey-Jumper, L. Boreta, S.E. Fogh, J.L. Nakamura, P.V. Theodosopoulos, J. Phillips, M. Daras, K. Tsai, P.K. Sneed, M.K. Aghi, D. Raleigh, S.E. Braunstein, A.R. Abate. Mutational Analysis and Single Cell Sequencing of Melanoma Brain Metastases. International Journal of Radiation Oncology • Biology • Physics. 2022 Nov 1; 114(3):e63-e64. |
Zhang P, Li X, Chen JY, Abate AR. Controlled fabrication of functional liver spheroids with microfluidic flow cytometric printing. Biofabrication. 2022 08 23; 14(4). |
DeVeale B, Liu L, Boileau R, Swindlehurst-Chan J, Marsh B, Freimer JW, Abate A, Blelloch R. G1/S restriction point coordinates phasic gene expression and cell differentiation. Nat Commun. 2022 06 27; 13(1):3696. |
Weisgerber DW, Hatori M, Li X, Abate AR. Polyhedral Particles with Controlled Concavity by Indentation Templating. Anal Chem. 2022 05 31; 94(21):7475-7482. |
Smith BJ, Li X, Shi ZJ, Abate A, Pollard KS. Scalable Microbial Strain Inference in Metagenomic Data Using StrainFacts. Front Bioinform. 2022; 2:867386. |
Sun C, Liu L, Pérez L, Li X, Liu Y, Xu P, Boritz EA, Mullins JI, Abate AR. Droplet-microfluidics-assisted sequencing of HIV proviruses and their integration sites in cells from people on antiretroviral therapy. Nat Biomed Eng. 2022 08; 6(8):1004-1012. |
Linfeng Xu, Xiangpeng Li, Wenzong Li, Kai-chun Chang, Hyunjun Yang, Nannan Tao, Pengfei Zhang, Emory M. Payne, Cyrus Modavi, Jacqueline Humphries, Chia-Wei Lu, Adam R. Abate. Microbowls with Controlled Concavity for Accurate Microscale Mass Spectrometry (Adv. Mater. 12/2022). Advanced Materials. 2022 Mar 24; 34(12):2270095. |
Hatori MN, Modavi C, Xu P, Weisgerber D, Abate AR. Dual-layered hydrogels allow complete genome recovery with nucleic acid cytometry. Biotechnol J. 2022 Apr; 17(4):e2100483. |
Xu L, Li X, Li W, Chang KC, Yang H, Tao N, Zhang P, Payne EM, Modavi C, Humphries J, Lu CW, Abate AR. Microbowls with Controlled Concavity for Accurate Microscale Mass Spectrometry. Adv Mater. 2022 Mar; 34(12):e2108194. |
Tran TM, Kim SC, Modavi C, Abate AR. Robotic automation of droplet microfluidics. Biomicrofluidics. 2022 Jan; 16(1):014102. |
Madrigal JL, Schoepp NG, Xu L, Powell CS, Delley CL, Siltanen CA, Danao J, Srinivasan M, Cole RH, Abate AR. Characterizing cell interactions at scale with made-to-order droplet ensembles (MODEs). Proc Natl Acad Sci U S A. 2022 02 01; 119(5). |
Kim SC, Haliburton JR, Gartner ZJ, Abate AR. Single-Cell Protein Profiling by Microdroplet Barcoding and Next-Generation Sequencing. Methods Mol Biol. 2022; 2386:101-111. |
Chang KC, Rhodes CT, Zhang JQ, Moseley MC, Cardona SM, Huang SA, Rawls A, Lemmon VP, Berger MS, Abate AR, Lin CA. The chromatin repressors EZH2 and Suv4-20h coregulate cell fate specification during hippocampal development. FEBS Lett. 2022 Feb; 596(3):294-308. |
Xu L, Chang KC, Payne EM, Modavi C, Liu L, Palmer CM, Tao N, Alper HS, Kennedy RT, Cornett DS, Abate AR. Mapping enzyme catalysis with metabolic biosensing. Nat Commun. 2021 11 23; 12(1):6803. |
Harish Vasudevan, Sydney Lastella, Matthew Sale, Timothy Casey-Clyde, Benjamin Demaree, Cyrille Delley, Calixto Lucas, Stephen Magill, John Liu, William Chen, Steve Braunstein, Alyssa Reddy, Arie Perry, Line Jacques, Melike Pekmezci, Adam Abate, Frank McCormick, David Raleigh. CSIG-01. EPIGENETIC REPROGRAMMING DRIVES MALIGNANT PERIPHERAL NERVE SHEATH TUMOR (MPNST) DE-DIFFERENTIATION AND TREATMENT RESISTANCE. Neuro-Oncology. 2021 Nov 12; 23(Supplement_6):vi33-vi33. |
Modavi C, Abate A. Change can be SCARI. Nat Chem Biol. 2021 11; 17(11):1119-1120. |
Sun C, Liu L, Vasudevan HN, Chang KC, Abate AR. Accurate Bulk Quantitation of Droplet Digital Polymerase Chain Reaction. Anal Chem. 2021 07 27; 93(29):9974-9979. |
Delley CL, Abate AR. Modular barcode beads for microfluidic single cell genomics. Sci Rep. 2021 05 25; 11(1):10857. |
Sun C, Chang KC, Abate AR. Sequencing Ultrarare Targets with Compound Nucleic Acid Cytometry. Anal Chem. 2021 05 25; 93(20):7422-7429. |
Le Coz C, Nguyen DN, Su C, Nolan BE, Albrecht AV, Xhani S, Sun D, Demaree B, Pillarisetti P, Khanna C, Wright F, Chen PA, Yoon S, Stiegler AL, Maurer K, Garifallou JP, Rymaszewski A, Kroft SH, Olson TS, Seif AE, Wertheim G, Grant SFA, Vo LT, Puck JM, Sullivan KE, Routes JM, Zakharova V, Shcherbina A, Mukhina A, Rudy NL, Hurst ACE, Atkinson TP, Boggon TJ, Hakonarson H, Abate AR, Hajjar J, Nicholas SK, Lupski JR, Verbsky J, Chinn IK, Gonzalez MV, Wells AD, Marson A, Poon GMK, Romberg N. Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients. J Exp Med. 2021 07 05; 218(7). |
Clark IC, Gutiérrez-Vázquez C, Wheeler MA, Li Z, Rothhammer V, Linnerbauer M, Sanmarco LM, Guo L, Blain M, Zandee SEJ, Chao CC, Batterman KV, Schwabenland M, Lotfy P, Tejeda-Velarde A, Hewson P, Manganeli Polonio C, Shultis MW, Salem Y, Tjon EC, Fonseca-Castro PH, Borucki DM, Alves de Lima K, Plasencia A, Abate AR, Rosene DL, Hodgetts KJ, Prinz M, Antel JP, Prat A, Quintana FJ. Barcoded viral tracing of single-cell interactions in central nervous system inflammation. Science. 2021 04 23; 372(6540). |
Zhang P, Chang KC, Abate AR. Precision ejection of microfluidic droplets into air with a superhydrophobic outlet. Lab Chip. 2021 04 20; 21(8):1484-1491. |
Clark IC, Mensa B, Ochs CJ, Schmidt NW, Mravic M, Quintana FJ, DeGrado WF, Abate AR. Protein design-scapes generated by microfluidic DNA assembly elucidate domain coupling in the bacterial histidine kinase CpxA. Proc Natl Acad Sci U S A. 2021 03 23; 118(12). |
Demaree B, Delley CL, Vasudevan HN, Peretz CAC, Ruff D, Smith CC, Abate AR. Joint profiling of DNA and proteins in single cells to dissect genotype-phenotype associations in leukemia. Nat Commun. 2021 03 11; 12(1):1583. |
Daniel W. Weisgerber, Makiko N. Hatori, Adam R. Abate. Particle Templated Emulsification enables Microfluidic-Free Droplet Assays. Journal of Visualized Experiments. 2021 Mar 9; (169). |
Weisgerber DW, Hatori MN, Abate AR. Particle Templated Emulsification enables Microfluidic-Free Droplet Assays. J Vis Exp. 2021 03 09; (169). |
Cabral KA, Patterson DM, Scheideler OJ, Cole R, Abate AR, Schaffer DV, Sohn LL, Gartner ZJ. Simple, Affordable, and Modular Patterning of Cells using DNA. J Vis Exp. 2021 02 24; (168). |
Katelyn A. Cabral, David M. Patterson, Olivia J. Scheideler, Russell Cole, Adam R. Abate, David V. Schaffer, Lydia L. Sohn, Zev J. Gartner. Simple, Affordable, and Modular Patterning of Cells using DNA. Journal of Visualized Experiments. 2021 Feb 24; (168). |
Zhang JQ, Siltanen CA, Dolatmoradi A, Sun C, Chang KC, Cole RH, Gartner ZJ, Abate AR. High diversity droplet microfluidic libraries generated with a commercial liquid spotter. Sci Rep. 2021 02 23; 11(1):4351. |
Sun C, Liu L, Vasudevan HN, Chang KC, Abate AR. Accurate bulk quantitation of droplet digital PCR. bioRxiv. 2021 Jan 15. |
Vasudevan HN, Xu P, Servellita V, Miller S, Liu L, Gopez A, Chiu CY, Abate AR. Digital droplet PCR accurately quantifies SARS-CoV-2 viral load from crude lysate without nucleic acid purification. Sci Rep. 2021 01 12; 11(1):780. |
Finbloom JA, Demaree B, Abate AR, Desai TA. Networks of High Aspect Ratio Particles to Direct Colloidal Assembly Dynamics and Cellular Interactions. Adv Funct Mater. 2020 Nov 25; 30(48). |
Zhang P, Abate AR. High-Definition Single-Cell Printing: Cell-by-Cell Fabrication of Biological Structures. Adv Mater. 2020 Dec; 32(52):e2005346. |
Miles LA, Bowman RL, Merlinsky TR, Csete IS, Ooi AT, Durruthy-Durruthy R, Bowman M, Famulare C, Patel MA, Mendez P, Ainali C, Demaree B, Delley CL, Abate AR, Manivannan M, Sahu S, Goldberg AD, Bolton KL, Zehir A, Rampal R, Carroll MP, Meyer SE, Viny AD, Levine RL. Single-cell mutation analysis of clonal evolution in myeloid malignancies. Nature. 2020 11; 587(7834):477-482. |
Clark IC, Delley CL, Sun C, Thakur R, Stott SL, Thaploo S, Li Z, Quintana FJ, Abate AR. Targeted Single-Cell RNA and DNA Sequencing With Fluorescence-Activated Droplet Merger. Anal Chem. 2020 11 03; 92(21):14616-14623. |
Magill ST, Vasudevan HN, Seo K, Villanueva-Meyer JE, Choudhury A, John Liu S, Pekmezci M, Findakly S, Hilz S, Lastella S, Demaree B, Braunstein SE, Bush NAO, Aghi MK, Theodosopoulos PV, Sneed PK, Abate AR, Berger MS, McDermott MW, Lim DA, Ullian EM, Costello JF, Raleigh DR. Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma. Nat Commun. 2020 09 23; 11(1):4803. |
Vasudevan H, Xu P, Servellita V, Miller S, Liu L, Gopez A, Chiu CY, Abate AR. Digital droplet PCR accurately quantifies SARS-CoV-2 viral load from crude lysate without nucleic acid purification. medRxiv. 2020 Sep 03. |
Delley CL, Abate AR. Microfluidic particle zipper enables controlled loading of droplets with distinct particle types. Lab Chip. 2020 07 14; 20(14):2465-2472. |
Jesse Q. Zhang, Kai-Chun Chang, Leqian Liu, Zev J. Gartner, Adam R. Abate. High Throughput Yeast Strain Phenotyping with Droplet-Based RNA Sequencing. Journal of Visualized Experiments. 2020 May 21; (159). |
Zhang JQ, Chang KC, Liu L, Gartner ZJ, Abate AR. High Throughput Yeast Strain Phenotyping with Droplet-Based RNA Sequencing. J Vis Exp. 2020 05 21; (159). |
Xu P, Modavi C, Demaree B, Twigg F, Liang B, Sun C, Zhang W, Abate AR. Microfluidic automated plasmid library enrichment for biosynthetic gene cluster discovery. Nucleic Acids Res. 2020 05 07; 48(8):e48. |
Zhang JQ, Siltanen CA, Liu L, Chang KC, Gartner ZJ, Abate AR. Linked optical and gene expression profiling of single cells at high-throughput. Genome Biol. 2020 02 24; 21(1):49. |
Liu SJ, Magill ST, Vasudevan HN, Hilz S, Villanueva-Meyer JE, Lastella S, Daggubati V, Spatz J, Choudhury A, Orr BA, Demaree B, Seo K, Ferris SP, Abate AR, Oberheim Bush NA, Bollen AW, McDermott MW, Costello JF, Raleigh DR. Multiplatform Molecular Profiling Reveals Epigenomic Intratumor Heterogeneity in Ependymoma. Cell Rep. 2020 02 04; 30(5):1300-1309.e5. |
Kim JH, Kim SC, Kline MA, Grzincic EM, Tresca BW, Cardiel J, Karbaschi M, Dehigaspitiya DC, Chen Y, Udumula V, Jian T, Murray DJ, Yun L, Connolly MD, Liu J, Ren G, Chen CL, Kirshenbaum K, Abate AR, Zuckermann RN. Discovery of Stable and Selective Antibody Mimetics from Combinatorial Libraries of Polyvalent, Loop-Functionalized Peptoid Nanosheets. ACS Nano. 2020 01 28; 14(1):185-195. |
E. Boritz, I. Clark, A. Abate, F. Quintana, S. Deeks, D. Douek. OP 1.3 Single-cell transcriptome sequencing of latently-infected cells ex vivo using PCR-activated cell sorting (PACS). Journal of virus eradication. 2019 Dec 1; 5:1-2. |
Benjamin Demaree, Cyrille Delley, Cheryl Peretz, Harish Vasudevan, David Ruff, Aik Ooi, Catherine C. Smith, Adam Abate. Combined Single-Cell DNA Genotyping and Protein Quantification (DAb-seq) in Acute Myeloid Leukemias Reveals Distinct Immunophenotypic Subsets Among Pathogenic Clones. Blood. 2019 Nov 13; 134(Supplement_1):2088-2088. |
Stephen Magill, Harish Vasudevan, Kyounghee Seo, S John Liu, Stephanie Hilz, Javier Villanueva-Meyer, Abrar Choudhury, Benjamin Demaree, Daniel Lim, Steve Braunstein, Nancy Ann Oberheim-Bush, Erik Ullian, Manish Aghi, Philip Theodosopoulos, Patricia Sneed, Adam Abate, Mitchel Berger, Mike McDermott, Joseph Costello, David Raleigh. TMOD-27. A NEURAL CREST CELL SUBPOPULATION UNDERLIES INTRATUMOR HETEROGENEITY IN MENINGIOMA. Neuro-Oncology. 2019 Nov 11; 21(Supplement_6):vi268-vi268. |
Murray DJ, Kim JH, Grzincic EM, Kim SC, Abate AR, Zuckermann RN. Uniform, Large-Area, Highly Ordered Peptoid Monolayer and Bilayer Films for Sensing Applications. Langmuir. 2019 10 22; 35(42):13671-13680. |
Samy KE, Levy ES, Phong K, Demaree B, Abate AR, Desai TA. Human intestinal spheroids cultured using Sacrificial Micromolding as a model system for studying drug transport. Sci Rep. 2019 07 09; 9(1):9936. |
Benjamin Demaree, Cyrille Delley, David Ruff, Sebastian Treusch, Dennis Eastburn, Keith Jones, Adam Abate. Abstract 3527: Combined high-throughput DNA genotyping and protein quantification in single cancer cells. Molecular and Cellular Biology / Genetics. 2019 Jul 1; 3527-3527. |
D. Eastburn, C. Delley, B. Demaree, D. Dhingra, P. Mendez, D. Ruff, A. Abate. HIGH-RESOLUTION CLONAL ANALYSIS OF TUMORS WITH SIMULTANEOUS SINGLE-CELL DNA SEQUENCING AND CELL SURFACE PHENOTYPING. HemaSphere. 2019 Jun 1; 3:439. |
Liu L, Dalal CK, Heineike BM, Abate AR. High throughput gene expression profiling of yeast colonies with microgel-culture Drop-seq. Lab Chip. 2019 05 14; 19(10):1838-1849. |
Aran D, Looney AP, Liu L, Wu E, Fong V, Hsu A, Chak S, Naikawadi RP, Wolters PJ, Abate AR, Butte AJ, Bhattacharya M. Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage. Nat Immunol. 2019 02; 20(2):163-172. |
Demaree B, Weisgerber D, Dolatmoradi A, Hatori M, Abate AR. Direct quantification of EGFR variant allele frequency in cell-free DNA using a microfluidic-free digital droplet PCR assay. Methods Cell Biol. 2018; 148:119-131. |
Clark IC, Abate AR. Microfluidic bead encapsulation above 20 kHz with triggered drop formation. Lab Chip. 2018 12 07; 18(23):3598-3605. |
Hatori MN, Kim SC, Abate AR. Particle-Templated Emulsification for Microfluidics-Free Digital Biology. Anal Chem. 2018 08 21; 90(16):9813-9820. |
Benjamin Demaree, Daniel Weisgerber, Freeman Lan, Adam R. Abate. An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing. Journal of Visualized Experiments. 2018 May 23; (135). |
Demaree B, Weisgerber D, Lan F, Abate AR. An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing. J Vis Exp. 2018 05 23; (135). |
Siltanen CA, Cole RH, Poust S, Chao L, Tyerman J, Kaufmann-Malaga B, Ubersax J, Gartner ZJ, Abate AR. An Oil-Free Picodrop Bioassay Platform for Synthetic Biology. Sci Rep. 2018 05 21; 8(1):7913. |
Wagner JM, Liu L, Yuan SF, Venkataraman MV, Abate AR, Alper HS. A comparative analysis of single cell and droplet-based FACS for improving production phenotypes: Riboflavin overproduction in Yarrowia lipolytica. Metab Eng. 2018 05; 47:346-356. |
Clark IC, Thakur R, Abate AR. Concentric electrodes improve microfluidic droplet sorting. Lab Chip. 2018 02 27; 18(5):710-713. |
Delley CL, Liu L, Sarhan MF, Abate AR. Combined aptamer and transcriptome sequencing of single cells. Sci Rep. 2018 02 13; 8(1):2919. |
Kim SC, Clark IC, Shahi P, Abate AR. Single-Cell RT-PCR in Microfluidic Droplets with Integrated Chemical Lysis. Anal Chem. 2018 01 16; 90(2):1273-1279. |
Sukovich DJ, Kim SC, Ahmed N, Abate AR. Bulk double emulsification for flow cytometric analysis of microfluidic droplets. Analyst. 2017 Dec 04; 142(24):4618-4622. |
C. Sun, J. Mullins, A. Abate. PP1.1 Whole genome sequencing of single HIV provirus and its proviral integration site for the study of HIV latency. Journal of virus eradication. 2017 Dec 1; 3:3-4. |
Hori Y, Kantak C, Murray RM, Abate AR. Cell-free extract based optimization of biomolecular circuits with droplet microfluidics. Lab Chip. 2017 09 12; 17(18):3037-3042. |
Abatemarco J, Sarhan MF, Wagner JM, Lin JL, Liu L, Hassouneh W, Yuan SF, Alper HS, Abate AR. RNA-aptamers-in-droplets (RAPID) high-throughput screening for secretory phenotypes. Nat Commun. 2017 08 23; 8(1):332. |
Cole RH, Tang SY, Siltanen CA, Shahi P, Zhang JQ, Poust S, Gartner ZJ, Abate AR. Printed droplet microfluidics for on demand dispensing of picoliter droplets and cells. Proc Natl Acad Sci U S A. 2017 08 15; 114(33):8728-8733. |
Karbaschi M, Shahi P, Abate AR. Rapid, chemical-free breaking of microfluidic emulsions with a hand-held antistatic gun. Biomicrofluidics. 2017 Jul; 11(4):044107. |
Kim SC, Premasekharan G, Clark IC, Gemeda HB, Paris PL, Abate AR. Measurement of copy number variation in single cancer cells using rapid-emulsification digital droplet MDA. Microsyst Nanoeng. 2017; 3. |
Clark IC, Abate AR. Finding a helix in a haystack: nucleic acid cytometry with droplet microfluidics. Lab Chip. 2017 06 13; 17(12):2032-2045. |
Lan F, Demaree B, Ahmed N, Abate AR. Single-cell genome sequencing at ultra-high-throughput with microfluidic droplet barcoding. Nat Biotechnol. 2017 Jul; 35(7):640-646. |
Haliburton JR, Kim SC, Clark IC, Sperling RA, Weitz DA, Abate AR. Efficient extraction of oil from droplet microfluidic emulsions. Biomicrofluidics. 2017 May; 11(3):034111. |
Shahi P, Kim SC, Haliburton JR, Gartner ZJ, Abate AR. Abseq: Ultrahigh-throughput single cell protein profiling with droplet microfluidic barcoding. Sci Rep. 2017 03 14; 7:44447. |
Haliburton JR, Shao W, Deutschbauer A, Arkin A, Abate AR. Genetic interaction mapping with microfluidic-based single cell sequencing. PLoS One. 2017; 12(2):e0171302. |
Sukovich DJ, Lance ST, Abate AR. Sequence specific sorting of DNA molecules with FACS using 3dPCR. Sci Rep. 2017 01 04; 7:39385. |
Zihao Yan, Iain C. Clark, Adam R. Abate. Rapid Encapsulation of Cell and Polymer Solutions with Bubble-Triggered Droplet Generation. Macromolecular Chemistry and Physics. 2017 Jan 1; 218(2):1600297. |
Lim SW, Lance ST, Stedman KM, Abate AR. PCR-activated cell sorting as a general, cultivation-free method for high-throughput identification and enrichment of virus hosts. J Virol Methods. 2017 04; 242:14-21. |
Lance ST, Sukovich DJ, Stedman KM, Abate AR. Peering below the diffraction limit: robust and specific sorting of viruses with flow cytometry. Virol J. 2016 12 01; 13(1):201. |
Ahmed N, Sukovich D, Abate AR. Operation of Droplet-Microfluidic Devices with a Lab Centrifuge. Micromachines (Basel). 2016 Sep 06; 7(9). |
Lan F, Haliburton JR, Yuan A, Abate AR. Droplet barcoding for massively parallel single-molecule deep sequencing. Nat Commun. 2016 06 29; 7:11784. |
Cole RH, Gartner ZJ, Abate AR. Multicolor Fluorescence Detection for Droplet Microfluidics Using Optical Fibers. J Vis Exp. 2016 05 05; (111). |
Russell H. Cole, Zev J. Gartner, Adam R. Abate. Multicolor Fluorescence Detection for Droplet Microfluidics Using Optical Fibers. Journal of Visualized Experiments. 2016 May 5; (111). |
de Lange N, Tran TM, Abate AR. Electrical lysis of cells for detergent-free droplet assays. Biomicrofluidics. 2016 Mar; 10(2):024114. |
Cole RH, Tran TM, Abate AR. Double Emulsion Generation Using a Polydimethylsiloxane (PDMS) Co-axial Flow Focus Device. J Vis Exp. 2015 Dec 25; (106):e53516. |
Sidore AM, Lan F, Lim SW, Abate AR. Enhanced sequencing coverage with digital droplet multiple displacement amplification. Nucleic Acids Res. 2016 Apr 20; 44(7):e66. |
Kim SC, Sukovich DJ, Abate AR. Patterning microfluidic device wettability with spatially-controlled plasma oxidation. Lab Chip. 2015 Aug 07; 15(15):3163-9. |
Cole RH, de Lange N, Gartner ZJ, Abate AR. Compact and modular multicolour fluorescence detector for droplet microfluidics. Lab Chip. 2015 Jul 07; 15(13):2754-8. |
Romero PA, Tran TM, Abate AR. Dissecting enzyme function with microfluidic-based deep mutational scanning. Proc Natl Acad Sci U S A. 2015 Jun 09; 112(23):7159-64. |
Eastburn DJ, Huang Y, Pellegrino M, Sciambi A, Ptácek LJ, Abate AR. Microfluidic droplet enrichment for targeted sequencing. Nucleic Acids Res. 2015 Jul 27; 43(13):e86. |
Lim SW, Tran TM, Abate AR. PCR-activated cell sorting for cultivation-free enrichment and sequencing of rare microbes. PLoS One. 2015; 10(1):e0113549. |
Sciambi A, Abate AR. Accurate microfluidic sorting of droplets at 30 kHz. Lab Chip. 2015 Jan 07; 15(1):47-51. |
Ochs CJ, Abate AR. Rapid modulation of droplet composition with pincer microvalves. Lab Chip. 2015 Jan 07; 15(1):52-6. |
Stieglitz E, Troup CB, Gelston LC, Haliburton J, Chow ED, Yu KB, Akutagawa J, Taylor-Weiner AN, Liu YL, Wang YD, Beckman K, Emanuel PD, Braun BS, Abate A, Gerbing RB, Alonzo TA, Loh ML. Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia. Blood. 2015 Jan 15; 125(3):516-24. |
Eastburn DJ, Sciambi A, Abate AR. Identification and genetic analysis of cancer cells with PCR-activated cell sorting. Nucleic Acids Res. 2014; 42(16):e128. |
O'Donovan B, Tran T, Sciambi A, Abate A. Picoinjection of microfluidic drops without metal electrodes. J Vis Exp. 2014 Apr 18; (86). |
Sciambi A, Abate AR. Generating electric fields in PDMS microfluidic devices with salt water electrodes. Lab Chip. 2014 Aug 07; 14(15):2605-9. |
Tran TM, Cater S, Abate AR. Coaxial flow focusing in poly(dimethylsiloxane) microfluidic devices. Biomicrofluidics. 2014 Jan; 8(1):016502. |
Abate AR, Hung T, Sperling RA, Mary P, Rotem A, Agresti JJ, Weiner MA, Weitz DA. DNA sequence analysis with droplet-based microfluidics. Lab Chip. 2013 Dec 21; 13(24):4864-9. |
Lim SW, Abate AR. Ultrahigh-throughput sorting of microfluidic drops with flow cytometry. Lab Chip. 2013 Dec 07; 13(23):4563-72. |
Eastburn DJ, Sciambi A, Abate AR. Ultrahigh-throughput Mammalian single-cell reverse-transcriptase polymerase chain reaction in microfluidic drops. Anal Chem. 2013 Aug 20; 85(16):8016-21. |
Sciambi A, Abate AR. Adding reagent to droplets with controlled rupture of encapsulated double emulsions. Biomicrofluidics. 2013; 7(4):44112. |
Eastburn DJ, Sciambi A, Abate AR. Picoinjection enables digital detection of RNA with droplet rt-PCR. PLoS One. 2013; 8(4):e62961. |
van Steijn V, Korczyk PM, Derzsi L, Abate AR, Weitz DA, Garstecki P. Block-and-break generation of microdroplets with fixed volume. Biomicrofluidics. 2013; 7(2):24108. |
T M Tran, F Lan, C S Thompson, A R Abate. From tubes to drops: droplet-based microfluidics for ultrahigh-throughput biology. Journal of Physics D. 2013 Mar 20; 46(11):114004. |
Thompson CS, Abate AR. Adhesive-based bonding technique for PDMS microfluidic devices. Lab Chip. 2013 Feb 21; 13(4):632-5. |
Romero PA, Abate AR. Flow focusing geometry generates droplets through a plug and squeeze mechanism. Lab Chip. 2012 Dec 21; 12(24):5130-2. |
Rotem A, Abate AR, Utada AS, Van Steijn V, Weitz DA. Drop formation in non-planar microfluidic devices. Lab Chip. 2012 Nov 07; 12(21):4263-8. |
O'Donovan B, Eastburn DJ, Abate AR. Electrode-free picoinjection of microfluidic drops. Lab Chip. 2012 Oct 21; 12(20):4029-32. |
Duncanson WJ, Lin T, Abate AR, Seiffert S, Shah RK, Weitz DA. Microfluidic synthesis of advanced microparticles for encapsulation and controlled release. Lab Chip. 2012 Jun 21; 12(12):2135-45. |
Abate AR, Mary P, van Steijn V, Weitz DA. Experimental validation of plugging during drop formation in a T-junction. Lab Chip. 2012 Apr 21; 12(8):1516-21. |
Romanowsky MB, Abate AR, Rotem A, Holtze C, Weitz DA. High throughput production of single core double emulsions in a parallelized microfluidic device. Lab Chip. 2012 Feb 21; 12(4):802-7. |
Adam R. Abate, Lloyd Han, Lihua Jin, Zhigang Suo, David A. Weitz. Measuring the elastic modulus of microgels using microdrops. Soft Matter. 2012 Jan 1; 8(39):10032-10035. |
Liu T, Seiffert S, Thiele J, Abate AR, Weitz DA, Richtering W. Non-coalescence of oppositely charged droplets in pH-sensitive emulsions. Proc Natl Acad Sci U S A. 2012 Jan 10; 109(2):384-9. |
Abate AR, Rotem A, Thiele J, Weitz DA. Efficient encapsulation with plug-triggered drop formation. Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Sep; 84(3 Pt 1):031502. |
Knowles TP, White DA, Abate AR, Agresti JJ, Cohen SI, Sperling RA, De Genst EJ, Dobson CM, Weitz DA. Observation of spatial propagation of amyloid assembly from single nuclei. Proc Natl Acad Sci U S A. 2011 Sep 06; 108(36):14746-51. |
Thiele J, Windbergs M, Abate AR, Trebbin M, Shum HC, Förster S, Weitz DA. Early development drug formulation on a chip: fabrication of nanoparticles using a microfluidic spray dryer. Lab Chip. 2011 Jul 21; 11(14):2362-8. |
Mary P, Chen A, Chen I, Abate AR, Weitz DA. On-chip background noise reduction for cell-based assays in droplets. Lab Chip. 2011 Jun 21; 11(12):2066-70. |
Abate AR, Weitz DA. Faster multiple emulsification with drop splitting. Lab Chip. 2011 Jun 07; 11(11):1911-5. |
Mary P, Abate AR, Agresti JJ, Weitz DA. Controlling droplet incubation using close-packed plug flow. Biomicrofluidics. 2011 Apr 04; 5(2):24101. |
Abate AR, Weitz DA. Air-bubble-triggered drop formation in microfluidics. Lab Chip. 2011 May 21; 11(10):1713-6. |
Abate AR, Weitz DA. Syringe-vacuum microfluidics: A portable technique to create monodisperse emulsions. Biomicrofluidics. 2011 Mar 16; 5:14107. |
Abate AR, Kutsovsky M, Seiffert S, Windbergs M, Pinto LF, Rotem A, Utada AS, Weitz DA. Synthesis of monodisperse microparticles from non-Newtonian polymer solutions with microfluidic devices. Adv Mater. 2011 Apr 19; 23(15):1757-60. |
Abate AR, Thiele J, Weitz DA. One-step formation of multiple emulsions in microfluidics. Lab Chip. 2011 Jan 21; 11(2):253-8. |
Abate AR, Hung T, Mary P, Agresti JJ, Weitz DA. High-throughput injection with microfluidics using picoinjectors. Proc Natl Acad Sci U S A. 2010 Nov 09; 107(45):19163-6. |
Thiele J, Abate AR, Shum HC, Bachtler S, Förster S, Weitz DA. Fabrication of polymersomes using double-emulsion templates in glass-coated stamped microfluidic devices. Small. 2010 Aug 16; 6(16):1723-7. |
Abate AR, Thiele J, Weinhart M, Weitz DA. Patterning microfluidic device wettability using flow confinement. Lab Chip. 2010 Jul 21; 10(14):1774-6. |
Adam R. Abate, Jeremy J. Agresti, David A. Weitz. Microfluidic sorting with high-speed single-layer membrane valves. Applied Physics Letters. 2010 May 17; 96(20):203509. |
Seiffert S, Thiele J, Abate AR, Weitz DA. Smart microgel capsules from macromolecular precursors. J Am Chem Soc. 2010 May 12; 132(18):6606-9. |
Romanowsky MB, Heymann M, Abate AR, Krummel AT, Fraden S, Weitz DA. Functional patterning of PDMS microfluidic devices using integrated chemo-masks. Lab Chip. 2010 Jun 21; 10(12):1521-4. |
Agresti JJ, Antipov E, Abate AR, Ahn K, Rowat AC, Baret JC, Marquez M, Klibanov AM, Griffiths AD, Weitz DA. Ultrahigh-throughput screening in drop-based microfluidics for directed evolution. Proc Natl Acad Sci U S A. 2010 Mar 02; 107(9):4004-9. |
Schonbrun E, Abate AR, Steinvurzel PE, Weitz DA, Crozier KB. High-throughput fluorescence detection using an integrated zone-plate array. Lab Chip. 2010 Apr 07; 10(7):852-6. |
Shum HC, Abate AR, Lee D, Studart AR, Wang B, Chen CH, Thiele J, Shah RK, Krummel A, Weitz DA. Droplet microfluidics for fabrication of non-spherical particles. Macromol Rapid Commun. 2010 Jan 18; 31(2):108-18. |
A. R. Abate, D. A. Weitz. Multiple emulsions: Small 18/2009. Small. 2009 Sep 18; 5(18):na-na. |
Abate AR, Weitz DA. High-order multiple emulsions formed in poly(dimethylsiloxane) microfluidics. Small. 2009 Sep; 5(18):2030-2. |
Chia-Hung Chen, Adam R. Abate, Daeyeon Lee, Eugene M. Terentjev, David A. Weitz. Magnetic Hydrogel Particles: Microfluidic Assembly of Magnetic Hydrogel Particles with Uniformly Anisotropic Structure (Adv. Mater. 31/2009). Advanced Materials. 2009 Aug 21; 21(31):na-na. |
Chia-Hung Chen, Adam R. Abate, Daeyeon Lee, Eugene M. Terentjev, David A. Weitz. Microfluidic Assembly of Magnetic Hydrogel Particles with Uniformly Anisotropic Structure. Advanced Materials. 2009 Aug 21; 21(31):3201-3204. |
Abate AR, Poitzsch A, Hwang Y, Lee J, Czerwinska J, Weitz DA. Impact of inlet channel geometry on microfluidic drop formation. Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Aug; 80(2 Pt 2):026310. |
Tang SK, Li Z, Abate AR, Agresti JJ, Weitz DA, Psaltis D, Whitesides GM. A multi-color fast-switching microfluidic droplet dye laser. Lab Chip. 2009 Oct 07; 9(19):2767-71. |
Abate AR, Chen CH, Agresti JJ, Weitz DA. Beating Poisson encapsulation statistics using close-packed ordering. Lab Chip. 2009 Sep 21; 9(18):2628-31. |
Franke T, Abate AR, Weitz DA, Wixforth A. Surface acoustic wave (SAW) directed droplet flow in microfluidics for PDMS devices. Lab Chip. 2009 Sep 21; 9(18):2625-7. |
Chen CH, Shah RK, Abate AR, Weitz DA. Janus particles templated from double emulsion droplets generated using microfluidics. Langmuir. 2009 Apr 21; 25(8):4320-3. |
Adam R. Abate, Mark B. Romanowsky, Jeremy J. Agresti, David A. Weitz. Valve-based flow focusing for drop formation. Applied Physics Letters. 2009 Jan 12; 94(2):023503. |
Abate AR, Durian DJ. Effective temperatures and activated dynamics for a two-dimensional air-driven granular system on two approaches to jamming. Phys Rev Lett. 2008 Dec 12; 101(24):245701. |
Abate AR, Krummel AT, Lee D, Marquez M, Holtze C, Weitz DA. Photoreactive coating for high-contrast spatial patterning of microfluidic device wettability. Lab Chip. 2008 Dec; 8(12):2157-60. |
A. R. Abate, D. A. Weitz. Single-layer membrane valves for elastomeric microfluidic devices. Applied Physics Letters. 2008 Jun 16; 92(24):243509. |
Abate AR, Lee D, Do T, Holtze C, Weitz DA. Glass coating for PDMS microfluidic channels by sol-gel methods. Lab Chip. 2008 Apr; 8(4):516-8. |
Abate AR, Katsuragi H, Durian DJ. Avalanche statistics and time-resolved grain dynamics for a driven heap. Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Dec; 76(6 Pt 1):061301. |
Abate AR, Durian DJ. Spatially heterogeneous dynamics in a granular system near jamming. Chaos. 2007 Dec; 17(4):041107. |
Abate AR, Durian DJ. Topological persistence and dynamical heterogeneities near jamming. Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Aug; 76(2 Pt 1):021306. |
Abate AR, Durian DJ. Approach to jamming in an air-fluidized granular bed. Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Sep; 74(3 Pt 1):031308. |
Abate AR, Durian DJ. Partition of energy for air-fluidized grains. Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Sep; 72(3 Pt 1):031305. |
Ambroso MA, Santore CR, Abate AR, Durian DJ. Penetration depth for shallow impact cratering. Phys Rev E Stat Nonlin Soft Matter Phys. 2005 May; 71(5 Pt 1):051305. |
Ojha RP, Abate AR, Durian DJ. Statistical characterization of the forces on spheres in an upflow of air. Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Jan; 71(1 Pt 2):016313. |
Abate A, Schröder H. Protease inhibitors protect macrophages from lipopolysaccharide-induced cytotoxicity: possible role for NF-kappaB. Life Sci. 1998; 62(12):1081-8. |
Podhaisky HP, Abate A, Polte T, Oberle S, Schröder H. Aspirin protects endothelial cells from oxidative stress--possible synergism with vitamin E. FEBS Lett. 1997 Nov 17; 417(3):349-51. |
Ullrich T, Oberle S, Abate A, Schröder H. Photoactivation of the nitric oxide donor SIN-1. FEBS Lett. 1997 Apr 07; 406(1-2):66-8. |