Stephen Kahl, PhD

Professor
Department of Pharmaceutical Chemistry
[email protected]
Phone: +1 415 476-4684
Fax: +1 415 476-0688
513 Parnassus Avenue, MSB, Rm 1122A
UCSF Box 0912
San Francisco, CA 94117
United States

Links

UCSF Profiles

Affiliations

Education programs

PharmD Degree Program

What I do

Since retiring from UCSF, I continue to teach and coordinate PC 121 and PC 157. I am also still a member of several other committees.

Departmental research area

chemical biology and medicinal chemistry

Research keywords

  • Boron Compounds
  • Antigens, Polyomavirus Transforming
  • Maximum Tolerated Dose
  • Aldehydes
  • Deuteroporphyrins
  • Phenylalanine
  • Boranes
  • Boron
  • Anions
  • Boron Neutron Capture Therapy
  • Lipoproteins
  • Metalloporphyrins
  • Boronic Acids
  • Rats, Inbred F344
  • Porphyrins

Publications

Koo MS, Ozawa T, Santos RA, Lamborn KR, Bollen AW, Deen DF, Kahl SB. Synthesis and comparative toxicology of a series of polyhedral borane anion-substituted tetraphenyl porphyrins. J Med Chem. 2007 Feb 22; 50(4):820-7.
Dozzo P, Kasar RA, Kahl SB. Simple, high-yield methods for the synthesis of aldehydes directly from o-, m-, and p-carborane and their further conversions. Inorg Chem. 2005 Oct 31; 44(22):8053-7.
Ozawa T, Afzal J, Lamborn KR, Bollen AW, Bauer WF, Koo MS, Kahl SB, Deen DF. Toxicity, biodistribution, and convection-enhanced delivery of the boronated porphyrin BOPP in the 9L intracerebral rat glioma model. Int J Radiat Oncol Biol Phys. 2005 Sep 01; 63(1):247-52.
Dagrosa MA, Viaggi M, Rebagliati RJ, Batistoni D, Kahl SB, Juvenal GJ, Pisarev MA. Biodistribution of boron compounds in an animal model of human undifferentiated thyroid cancer for boron neutron capture therapy. Mol Pharm. 2005 Mar-Apr; 2(2):151-6.
Dozzo P, Koo MS, Berger S, Forte TM, Kahl SB. Synthesis, characterization, and plasma lipoprotein association of a nucleus-targeted boronated porphyrin. J Med Chem. 2005 Jan 27; 48(2):357-9.
Ozawa T, Santos RA, Lamborn KR, Bauer WF, Koo MS, Kahl SB, Deen DF. In vivo evaluation of the boronated porphyrin TABP-1 in U-87 MG intracerebral human glioblastoma xenografts. Mol Pharm. 2004 Sep-Oct; 1(5):368-74.
Kasar RA, Knudsen GM, Kahl SB. Synthesis of 3-Amino-1-carboxy-o-carborane and an Improved, General Method for the Synthesis of All Three C-Amino-C-carboxycarboranes. Inorg Chem. 1999 Jun 14; 38(12):2936-2940.
Radel PA, Kahl SB. Enantioselective Synthesis of L- and D-Carboranylalanine. J Org Chem. 1996 Jul 12; 61(14):4582-4588.
Kahl SB, Li J. Synthesis and Characterization of a Boronated Metallophthalocyanine for Boron Neutron Capture Therapy. Inorg Chem. 1996 Jun 19; 35(13):3878-3880.