Department of Pharmaceutical Chemistry

Cataracts are the leading cause of blindness worldwide, the leading cause of vision loss in the United States, and cases are increasing with an aging population. Currently the condition can be treated with surgery—an expensive intervention that leaves most patients blinded in developing countries...

More than a quarter of all drugs work by targeting one of a large family of proteins called G-protein-coupled receptors (GPCRs). Hundreds of different GPCRs are embedded in cell membranes, converting stimuli from the outside world—neurotransmitters, hormones, even light—into intracellular signals...

Aashish Manglik, PhD of Stanford University presents:

"Structural insights into G protein coupled receptor function"

 

Strategic planning; Recently received research funding: cancer, Alzheimer's, HIV, type 2 diabetes (Kroetz, Keiser, Gross, Roy); Recent faculty publications: fibrosis, biofilms, gout (DeGrado, Yang, Giacomini); Collaborations and partnerships; Patient care: SB 493, scope of practice for California...

Ambika Bhagi-Damodaran of the University of Illinois at Urbana-Champaign, presents: 

“Understanding structure-function relations in heme-copper oxidase using myoglobin-based mimics”

UCSF School of Pharmacy faculty member Tejal Desai, PhD, has been newly elected to the National Academy of Medicine (NAM), formerly known as the Institute of Medicine (IOM).

The next frontier in developing therapies for cancer and other diseases could come through studying organ development or tumor growth in living humans. Problem is, there’s no ethical way of doing that using current technology.

Zev Gartner, PhD, has focused on the next best thing: His lab is...

Pharmaceutical Chemistry faculty members have published the following manuscripts between July and September 2015: