UCSF

Tagged: x-ray crystallography

How targeting a key SARS-CoV-2 enzyme could lead to an antiviral drug

The chemical fragments could bind to and disable an enzyme that helps the virus replicate.

Overcoming disease with moving pictures and molecular building blocks

Jaime Fraser delivered the 2020 Byers Award Lecture in Basic Science

Fraser appointed to Bowes Biomedical Investigator Program

Fraser developed several new tools for creating maps of macromolecules, a critical first step for finding new drugs.

Fraser named Searle Scholar, will shine new light on protein shapeshifting

Biophysicist James Fraser, PhD, has been named a 2014 Searle Scholar. His laboratory will be awarded $300,000 in funding over the next three years to support his research into more accurately and precisely describing the ways that protein molecules change shape to carry out the functions of life in...

James Fraser, PhD

Professor

I am a biophysicist. My research is focused on discovering the macromolecular structure and dynamics of proteins—defining conformational states essential for function and understanding transitions between these states.