Tagged: Pediatric Pharmacology

The Right Dose: How pharmacy researchers are making medicine more precise

Reprinted courtesy of UCSF Magazine.

In the pediatric bone marrow transplant clinic, pharmacist Janel Boyle’s past and present collide.

She drifts past young patients—many of them infants and toddlers—and notes their beaming smiles and balding heads. Her gaze shifts to the parents, their expressions tense but hopeful.

Janel Long-Boyle, PharmD, PhD

Associate Professor

I am a translational scientist with research interests that include pediatric cancer therapeutics, pharmacokinetics, pharmacodynamics, pharmacogenomics, and clinical trial design. The majority of my research is focused around the chemotherapeutic and immunosuppressive agents used in the conditioning regimens of pediatric hematopoietic cell transplantation (HCT). Specifically, I am interested in how patient specific covariates such as age, renal function, or genetic variants involved in drug metabolism or distribution may influence drug clearance in the pediatric HCT population.