UCSF

Tagged: meta-analysis

Research points to individualized treatments for curing TB

Tuberculosis is usually treated with a six month regimen of daily antibiotics, but millions of patients do not recover from the disease during treatment. Rada Savic’s team showed that adjusting the duration of this regimen based on disease severity could lead to better outcomes.

Analysis finds sponsorship biases in animal studies may differ from those in clinical trials

A new analysis of dozens of animal studies evaluating the effects of the cholesterol-lowering statin class of drugs on atherosclerosis found larger positive effects in studies not sponsored by the pharmaceutical industry as compared to those that were industry sponsored.

Conflicts of interest significantly underreported in systematic reviews of drug efficacy, safety

Systematic reviews seek to answer key questions about the relative effectiveness and safety of medical interventions by selecting, combining, and critically evaluating the research in published medical literature.

Study finds including unpublished FDA data alters drug effectiveness outcomes

Every year U.S. drug regulators approve dozens of new medicines as “safe and effective,” but just how effective are they? How well do they alleviate specific aspects of illness, whether light sensitivity from migraine headaches or itching from eczema?

Asthma genetics study finds new gene

A novel gene associated with the asthma susceptibility in African Americans was revealed by a U.S. consortium of asthma genetics researchers, including Esteban G. Burchard, MD, MPH, Department of Bioengineering and Therapeutic Sciences, UCSF Schools of Pharmacy and Medicine.