My primary interest is identification of genetic determinants of drug response through modern methods aimed at addressing pharmacogenomics research and translating that information into new diagnostics and treatment strategies at point-of-care.
My research seeks to understand the contribution of genetic variation to drug toxicity, to identify genetic biomarkers that can be used to guide effective use of drugs in the treatment of cancer and HIV, and to use genetics to unravel the molecular basis of drug-induced toxicity.
My research focuses on membrane transporters, which are of great importance to drug disposition and response. I am particularly interested in genetic variants in membrane transporters that are determinants of drug response and in harnessing transporters to enhance drug targeting.
During his illustrious half-century career, UCSF School of Pharmacy faculty member Leslie Benet, PhD, has authored more than 400 peer-reviewed publications, many helping to define the field of pharmacokinetics—how the body absorbs, distributes, metabolizes, and excretes medications—or as he once put it, “what the body does
Pharmacogenetics expert Kathy Giacomini, PhD, co-chair of the UCSF Department of Bioengineering and Therapeutic Sciences, is leading the UCSF arm of a research partnership in which her team will profile 2,000 prescription drugs against key molecules in the liver and kidney that are responsible for ferrying those dr
Kathy Giacomini, PhD, co-chair of the Department of Bioengineering and Therapeutic Sciences, UCSF Schools of Pharmacy and Medicine, will receive the 2010 Therapeutic Frontiers Lecture Award from the American College of Clinical Pharmacy on October 17, 2010, in Austin, Texas at ACCP's annual meeting.
Kathy Giacomini, PhD, co-chair of the UCSF Department of Bioengineering and Therapeutic Sciences and an expert in the field of pharmacogenomics, is leading two research projects funded by two grants totaling $15.1 million over the next five years to expand research into how genes affect an individual's response to medication and to strengthen a global network of researchers
Kathy Giacomini, PhD, and Carl Peck, MD, faculty members in the UCSF Department of Bioengineering and Therapeutic Sciences (BTS), received awards from the American Society for Clinical Pharmacology and Therapeutics (ASCPT) at the society's annual meeting held in National Harbor, Maryland, USA, March 18-21, 2009.
Kathy M. Giacomini, PhD, UCSF School of Pharmacy scientist, received the 2005 Paul Dawson Biotechnology Award in Cincinnati, Ohio on July 10, 2005 from the American Association of Colleges of Pharmacy (AACP). The award recognizes exceptional teaching and research in biotechnology.