My research focuses on computational methods for improving drug discovery. I was formally trained as a computer scientist and made a transition from applied defense research to the biomedical arena in a series of Bay Area startups.
Our lab develops new methods for drug discovery, adopting two strategies to do so. On the one hand, we reduce biology to its molecular components, and seek to change how these fit together using synthetic molecules we design. On the other hand, we investigate how the biological molecules operate together, both in health and disease. Both processes involve intensive modeling and close collaboration between theory and experiment.