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New Alzheimer’s drug is for those with mild cognitive impairment. But who has that disorder?

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September 26, 2021 at 8:00 a.m. EDT
Aduhelm was developed by Biogen, a U.S. multinational biotechnology company in Cambridge, Mass. (Brian Snyder/Reuters)

The approval of a controversial new drug for Alzheimer’s disease, Aduhelm, is shining a spotlight on mild cognitive impairment (MCI) — problems with memory, attention, language or other cognitive tasks that exceed changes expected with normal aging.

After initially indicating that Aduhelm could be prescribed to anyone with dementia, the Food and Drug Administration now specifies that the prescription drug be given to individuals with MCI or early-stage Alzheimer’s, the groups in which the medication was studied.