My research focuses on membrane transporters, which are of great importance to drug disposition and response. I am particularly interested in genetic variants in membrane transporters that are determinants of drug response and in harnessing transporters to enhance drug targeting.
The path from scientific insight to a new drug used to treat patients is a long, expensive, inefficient, hazard-strewn obstacle course requiring many steps before the drug arrives at the pharmacy. Unfortunately, the specialists working at each of these steps do not necessarily have a clear vision of what goes on outside their own areas of expertise. As a result, they can be unaware of how the decisions they make impact other points in the cycle of drug or medical product development.
Kathy M. Giacomini, PhD, chair, department of biopharmaceutical sciences and Leslie Z. Benet, PhD, professor in the same department, were both honored at the Pharmaceutical Sciences World Congress, held May 29 to June 4, 2004 in Kyoto, Japan.