Deanna Kroetz, PhD

Phone: +1 415 476-1159
Fax: +1 415 514-4361

1550 4th Street, Bldg 19B, Rm 584E
UCSF Box 2911
San Francisco, CA 94158
United States

What I do

My research seeks to understand the contribution of genetic variation to drug toxicity, to identify genetic biomarkers that can be used to guide effective use of drugs in the treatment of cancer and HIV, and to use genetics to unravel the molecular basis of drug-induced toxicity.

My research expertise

Cancer therapy, HIV/AIDS, Multidrug resistance, Membrane transporters, Toxicity

Degrees

PhD, Pharmaceutics, University of Washington, 1990
BSc, Pharmacy, Ohio State University, 1985

Biography

The Kroetz lab has two major research areas. A major goal is to understand the role of genetic variation in determining drug response and toxicity. Integrated genomic and functional studies are focused on identifying genetic biomarkers of taxane-induced sensory peripheral neuropathy and response to antiretroviral therapies. A second area of research is on the role of cytochrome P450 eicosanoids in acute and chronic renal dysfunction. Animal and cellular studies are used to test whether inhibition of soluble epoxide hydrolase can be targeted for renoprotection.

Licensure and certifications

Registered Pharmacist, Ohio, 1985